| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | SABBY MANAGEMENT, LLC | 2,021,347 | 4,204,000 | 25.21% | ||
| 2 | Senvest Management, LLC | 1,591,367 | 3,310,000 | 19.85% | ||
| 3 | BVF INC/IL | 1,501,000 | 3,122,000 | 18.72% | ||
| 4 | ORBIMED ADVISORS LLC | 1,135,000 | 2,361,000 | 14.16% | ||
| 5 | Opaleye Management Inc. | 650,000 | 1,352,000 | 8.11% | ||
| 6 | SPHERA FUNDS MANAGEMENT LTD. | 600,000 | 1,248,000 | 7.48% | ||
| 7 | DEUTSCHE BANK AG\ | 191,850 | 399,000 | 2.39% | ||
| 8 | PERCEPTIVE ADVISORS LLC | 165,698 | 345,000 | 2.07% | ||
| 9 | RENAISSANCE TECHNOLOGIES LLC | 43,700 | 91,000 | 0.55% | ||
| 10 | Benchmark Capital Advisors | 40,000 | 83,000 | 0.50% | ||
| 11 | Bank of New York Mellon Corp | 17,800 | 37,000 | 0.22% | ||
| 12 | NEXT Financial Group, Inc | 17,500 | 30,000 | 0.18% | ||
| 13 | ROYAL BANK OF CANADA | 12,000 | 25,000 | 0.15% | ||
| 14 | Virtu KCG Holdings LLC | 11,962 | 25,000 | 0.15% | ||
| 15 | UBS AG | 10,000 | 21,000 | 0.13% | ||
| 16 | MORGAN STANLEY | 10,275 | 21,000 | 0.13% | ||
| 17 | WELLS FARGO & COMPANY/MN | 1,000 | 2,000 | 0.01% | ||
| 18 | AMERIPRISE FINANCIAL INC | 310 | 1,000 | 0.01% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
