| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | PRIMECAP MANAGEMENT CO/CA/ | 5,751,990 | 149,782,000 | 13.34% | ||
| 2 | MACQUARIE GROUP LTD | 5,375,031 | 139,966,000 | 12.47% | ||
| 3 | Essex Woodlands Management, Inc. | 3,150,000 | 82,026,000 | 7.31% | ||
| 4 | BLAIR WILLIAM & CO/IL | 2,659,412 | 69,250,000 | 6.17% | ||
| 5 | VANGUARD GROUP INC | 2,414,564 | 62,875,000 | 5.60% | ||
| 6 | Palo Alto Investors LP | 2,202,289 | 57,348,000 | 5.11% | ||
| 7 | BlackRock Fund Advisors | 2,088,353 | 54,381,000 | 4.84% | ||
| 8 | NEXT CENTURY GROWTH INVESTORS LLC | 1,761,581 | 45,871,000 | 4.09% | ||
| 9 | Assured Investment Management LLC | 1,607,941 | 41,871,000 | 3.73% | ||
| 10 | WELLINGTON MANAGEMENT GROUP LLP | 1,596,964 | 41,585,000 | 3.70% | ||
| 11 | BlackRock Institutional Trust Company, N.A. | 1,076,771 | 28,039,000 | 2.50% | ||
| 12 | MILLENNIUM MANAGEMENT LLC | 841,173 | 21,904,000 | 1.95% | ||
| 13 | ROYAL BANK OF CANADA | 766,073 | 19,949,000 | 1.78% | ||
| 14 | STATE STREET CORP | 745,893 | 19,420,000 | 1.73% | ||
| 15 | GENEVA CAPITAL MANAGEMENT LLC | 634,846 | 16,531,000 | 1.47% | ||
| 16 | NORTHERN TRUST CORP | 536,681 | 13,976,000 | 1.24% | ||
| 17 | OMT Capital Management LLC | 514,950 | 13,409,000 | 1.19% | ||
| 18 | BANK OF MONTREAL /CAN/ | 485,002 | 12,629,000 | 1.12% | ||
| 19 | Bank of New York Mellon Corp | 451,783 | 11,765,000 | 1.05% | ||
| 20 | MORGAN STANLEY | 446,434 | 11,626,000 | 1.04% | ||
| 21 | ROCKEFELLER FINANCIAL SERVICES INC | 445,407 | 11,598,000 | 1.03% | ||
| 22 | Cortina Asset Management, LLC | 431,684 | 11,241,000 | 1.00% | ||
| 23 | DEUTSCHE BANK AG\ | 322,950 | 8,409,000 | 0.75% | ||
| 24 | NORGES BANK | 314,502 | 8,190,000 | 0.73% | ||
| 25 | Grandeur Peak Global Advisors, LLC | 301,650 | 7,855,000 | 0.70% | ||
| 26 | D. E. Shaw & Co., Inc. | 299,118 | 7,789,000 | 0.69% | ||
| 27 | PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO | 258,089 | 6,721,000 | 0.60% | ||
| 28 | PRINCIPAL FINANCIAL GROUP INC | 227,068 | 5,913,000 | 0.53% | ||
| 29 | TIAA CREF INVESTMENT MANAGEMENT LLC | 198,370 | 5,166,000 | 0.46% | ||
| 30 | BARCLAYS PLC | 198,063 | 5,149,000 | 0.46% | ||
| 31 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 213,657 | 5,087,000 | 0.45% | ||
| 32 | Portolan Capital Management, LLC | 194,622 | 5,068,000 | 0.45% | ||
| 33 | GEODE CAPITAL MANAGEMENT, LLC | 194,346 | 5,060,000 | 0.45% | ||
| 34 | SEI TRUST CO | 185,412 | 4,828,000 | 0.43% | ||
| 35 | Pine River Capital Management L.P. | 178,771 | 4,655,000 | 0.41% | ||
| 36 | Cupps Capital Management, LLC | 175,994 | 4,582,000 | 0.41% | ||
| 37 | MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC | 167,491 | 4,361,000 | 0.39% | ||
| 38 | RUSSELL FRANK CO/ | 170,218 | 4,185,000 | 0.37% | ||
| 39 | CREDIT SUISSE AG/ | 158,217 | 4,120,000 | 0.37% | ||
| 40 | AMERIPRISE FINANCIAL INC | 142,463 | 3,710,000 | 0.33% | ||
| 41 | BlackRock Investment Management, LLC | 126,418 | 3,292,000 | 0.29% | ||
| 42 | Apex Capital Management | 125,565 | 3,270,000 | 0.29% | ||
| 43 | DENVER INVESTMENT ADVISORS LLC | 123,092 | 3,205,000 | 0.29% | ||
| 44 | THRIVENT FINANCIAL FOR LUTHERANS | 121,400 | 3,161,000 | 0.28% | ||
| 45 | Visium Asset Management, LP | 117,279 | 3,054,000 | 0.27% | ||
| 46 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 102,742 | 2,676,000 | 0.24% | ||
| 47 | Invesco Ltd. | 94,961 | 2,473,000 | 0.22% | ||
| 48 | Rhenman & Partners Asset Management AB | 89,916 | 2,341,000 | 0.21% | ||
| 49 | NEW YORK STATE COMMON RETIREMENT FUND | 83,900 | 2,185,000 | 0.19% | ||
| 50 | GOLDMAN SACHS GROUP INC | 82,266 | 2,142,000 | 0.19% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
