| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | PRIMECAP MANAGEMENT CO/CA/ | 4,708,590 | 605,431,000 | 11.82% | ||
| 2 | VANGUARD GROUP INC | 3,109,512 | 399,821,000 | 7.80% | ||
| 3 | Palo Alto Investors LP | 1,884,384 | 242,294,000 | 4.73% | ||
| 4 | BlackRock Fund Advisors | 1,631,879 | 209,827,000 | 4.10% | ||
| 5 | Essex Woodlands Management, Inc. | 1,450,000 | 186,441,000 | 3.64% | ||
| 6 | BlackRock Institutional Trust Company, N.A. | 1,177,198 | 151,364,000 | 2.95% | ||
| 7 | 1832 Asset Management L.P. | 1,124,000 | 141,407,000 | 2.76% | ||
| 8 | STATE STREET CORP | 1,098,438 | 141,235,000 | 2.76% | ||
| 9 | WELLINGTON MANAGEMENT GROUP LLP | 1,004,378 | 129,143,000 | 2.52% | ||
| 10 | LORD, ABBETT & CO. LLC | 861,257 | 110,740,000 | 2.16% | ||
| 11 | WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | 756,938 | 97,327,000 | 1.90% | ||
| 12 | Jackson Square Partners, LLC | 668,773 | 85,990,000 | 1.68% | ||
| 13 | RENAISSANCE TECHNOLOGIES LLC | 660,223 | 84,891,000 | 1.66% | ||
| 14 | OAK RIDGE INVESTMENTS LLC | 611,242 | 78,594,000 | 1.53% | ||
| 15 | BROWN CAPITAL MANAGEMENT LLC | 603,964 | 77,658,000 | 1.52% | ||
| 16 | GOLDMAN SACHS GROUP INC | 587,677 | 75,564,000 | 1.47% | ||
| 17 | BAILLIE GIFFORD & CO | 575,243 | 73,965,000 | 1.44% | ||
| 18 | Bank of New York Mellon Corp | 548,052 | 70,468,000 | 1.38% | ||
| 19 | EAGLE ASSET MANAGEMENT INC | 546,733 | 70,298,000 | 1.37% | ||
| 20 | ROYAL BANK OF CANADA | 505,354 | 64,979,000 | 1.27% | ||
| 21 | MACQUARIE GROUP LTD | 500,398 | 64,341,000 | 1.26% | ||
| 22 | NORGES BANK | 513,794 | 63,098,000 | 1.23% | ||
| 23 | JANUS HENDERSON GROUP PLC | 489,548 | 62,946,000 | 1.23% | ||
| 24 | SCOUT INVESTMENTS, INC. | 461,281 | 59,312,000 | 1.16% | ||
| 25 | NEXT CENTURY GROWTH INVESTORS LLC | 423,390 | 54,439,000 | 1.06% | ||
| 26 | BLAIR WILLIAM & CO/IL | 386,609 | 49,710,000 | 0.97% | ||
| 27 | NORTHERN TRUST CORP | 369,249 | 47,477,000 | 0.93% | ||
| 28 | CASTLEARK MANAGEMENT LLC | 362,427 | 46,601,000 | 0.91% | ||
| 29 | DEUTSCHE BANK AG\ | 333,434 | 42,870,000 | 0.84% | ||
| 30 | Nationwide Fund Advisors | 318,612 | 40,967,000 | 0.80% | ||
| 31 | D. E. Shaw & Co., Inc. | 304,149 | 39,108,000 | 0.76% | ||
| 32 | Granahan Investment Management, LLC | 301,083 | 38,713,000 | 0.76% | ||
| 33 | MORGAN STANLEY | 296,699 | 38,150,000 | 0.74% | ||
| 34 | VOYA INVESTMENT MANAGEMENT LLC | 296,651 | 38,143,000 | 0.74% | ||
| 35 | Mitsubishi UFJ Trust & Banking Corp | 291,560 | 37,489,000 | 0.73% | ||
| 36 | GEODE CAPITAL MANAGEMENT, LLC | 281,016 | 36,133,000 | 0.71% | ||
| 37 | Stephens Investment Management Group LLC | 272,241 | 35,005,000 | 0.68% | ||
| 38 | FIRST TRUST ADVISORS LP | 256,262 | 32,950,000 | 0.64% | ||
| 39 | SECTORAL ASSET MANAGEMENT INC | 253,745 | 32,627,000 | 0.64% | ||
| 40 | PRUDENTIAL FINANCIAL INC | 237,745 | 30,569,000 | 0.60% | ||
| 41 | ROCKEFELLER FINANCIAL SERVICES INC | 231,516 | 29,768,000 | 0.58% | ||
| 42 | OppenheimerFunds, Inc. | 213,261 | 27,421,000 | 0.54% | ||
| 43 | GUGGENHEIM CAPITAL LLC | 204,492 | 26,293,000 | 0.51% | ||
| 44 | Invesco Ltd. | 200,646 | 25,799,000 | 0.50% | ||
| 45 | NEW YORK STATE COMMON RETIREMENT FUND | 200,540 | 25,785,000 | 0.50% | ||
| 46 | EMERALD ACQUISITION LTD. | 196,206 | 25,227,000 | 0.49% | ||
| 47 | FRED ALGER MANAGEMENT, LLC | 193,809 | 24,920,000 | 0.49% | ||
| 48 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 189,907 | 24,419,000 | 0.48% | ||
| 49 | AMERIPRISE FINANCIAL INC | 178,739 | 22,981,000 | 0.45% | ||
| 50 | FMR LLC | 176,503 | 22,695,000 | 0.44% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
