| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | ELI LILLY & CO | 30,121 | 237,203,000 | 12.38% | Call | |
| 2 | SPDR S&P 500 ETF TR PUT | 8,415 | 176,319,000 | 9.20% | Put | |
| 3 | ISHARES TR | 13,600 | 156,359,000 | 8.16% | Put | |
| 4 | ABBVIE INC | 18,007 | 111,481,000 | 5.82% | Call | |
| 5 | HCA HOLDINGS INC | 9,291 | 71,550,000 | 3.73% | Call | |
| 6 | AMGEN INC | 3,942 | 59,978,000 | 3.13% | Put | |
| 7 | SAREPTA THERAPEUTICS INC | 29,250 | 55,780,000 | 2.91% | Put | |
| 8 | MONSANTO CALL | 5,334 | 55,159,000 | 2.88% | Call | |
| 9 | BIOGEN INC | 1,866 | 45,124,000 | 2.35% | Call | |
| 10 | REGENERON PHARMACEUTICALS INC | 1,160 | 40,511,000 | 2.11% | Put | |
| 11 | ELI LILLY & CO | 4,891 | 38,517,000 | 2.01% | Put | |
| 12 | PFIZER INC | 10,000 | 35,210,000 | 1.84% | Call | |
| 13 | JOHNSON & JOHNSON | 2,809 | 34,073,000 | 1.78% | Call | |
| 14 | DEXCOM INC | 4,214 | 33,430,000 | 1.74% | Put | |
| 15 | SAREPTA THERAPEUTICS INC CALL | 15,225 | 29,034,000 | 1.51% | Call | |
| 16 | REGENERON PHARMACEUTICALS | 71,525 | 24,979,000 | 1.30% | ||
| 17 | AMGEN INC | 154,082 | 23,444,000 | 1.22% | ||
| 18 | ABBOTT LABS | 5,000 | 19,655,000 | 1.03% | Put | |
| 19 | MANNKIND CORP | 52,978 | 18,271,000 | 0.95% | Put | |
| 20 | TEVA PHARMACEUTICAL INDUSTRIES LTD | 3,618 | 18,173,000 | 0.95% | Call | |
| 21 | TESARO INC | 2,158 | 18,138,000 | 0.95% | Call | |
| 22 | RETROPHIN INC | 9,445 | 16,822,000 | 0.88% | Call | |
| 23 | DYNAVAX TECHNOLOGIES CORP | 10,712 | 15,618,000 | 0.81% | Call | |
| 24 | ACADIA PHARMACEUTICALS INC | 4,674 | 15,172,000 | 0.79% | Call | |
| 25 | SAREPTA THERAPEUTICS INC | 783,497 | 14,941,000 | 0.78% | ||
| 26 | ABBVIE INC | 2,347 | 14,530,000 | 0.76% | Put | |
| 27 | SHIRE PLC | 698 | 12,849,000 | 0.67% | Call | |
| 28 | SHIRE PLC | 698 | 12,849,000 | 0.67% | Put | |
| 29 | SPDR GOLD TRUST | 1,000 | 12,652,000 | 0.66% | Call | |
| 30 | MEDICINES CO | 3,614 | 12,154,000 | 0.63% | Call | |
| 31 | MYLAN N.V. | 2,804 | 12,124,000 | 0.63% | Call | |
| 32 | SAGE THERAPEUTICS INC | 4,009 | 12,079,000 | 0.63% | Call | |
| 33 | SAGE THERAPEUTICS INC | 3,496 | 10,533,000 | 0.55% | Put | |
| 34 | ABBOTT LABS | 264,700 | 10,405,000 | 0.54% | ||
| 35 | SPDR S&P BIOTECH ETF | 1,858 | 10,050,000 | 0.52% | Put | |
| 36 | DEXCOM INC | 1,180 | 9,361,000 | 0.49% | Call | |
| 37 | DYNAVAX TECHNOLOGIES CORP | 5,942 | 8,663,000 | 0.45% | Put | |
| 38 | RETROPHIN INC | 4,826 | 8,595,000 | 0.45% | Put | |
| 39 | ACORDA THERAPEUTICS INC | 9,600,000 | 8,388,000 | 0.44% | PRN | |
| 40 | IONIS PHARMACEUTICALS INC | 3,600 | 8,384,000 | 0.44% | Call | |
| 41 | ALKERMES PLC | 1,335 | 7,930,000 | 0.41% | Call | |
| 42 | CORSICANTO LTD | 7,756,000 | 7,877,000 | 0.41% | PRN | |
| 43 | LEXICON PHARMACEUTICALS INC | 5,320 | 7,634,000 | 0.40% | Call | |
| 44 | NOVAVAX INC | 10,447 | 7,595,000 | 0.40% | Put | |
| 45 | ONCOBIOLOGICS INC | 2,068,968 | 7,035,000 | 0.37% | ||
| 46 | CELGENE CORP | 695 | 6,855,000 | 0.36% | Call | |
| 47 | TENAX THERAPEUTICS INC COM | 2,606,035 | 6,671,000 | 0.35% | ||
| 48 | LION BIOTECHNOLOGIES INC | 7,526 | 6,096,000 | 0.32% | Put | |
| 49 | BIO PATH HOLDINGS INC | 2,988,295 | 5,947,000 | 0.31% | ||
| 50 | INTRA CELLULAR THERAPIES INC | 1,467 | 5,695,000 | 0.30% | Put |
Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001144204-16-119067, filed 2016.08.15).
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
