| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | ELI LILLY & CO | 23,675 | 174,130,000 | 10.13% | Call | |
| 2 | SPDR S&P 500 ETF TR PUT | 6,000 | 134,118,000 | 7.80% | Put | |
| 3 | ISHARES TR | 7,419 | 100,045,000 | 5.82% | Put | |
| 4 | REGENERON PHARMACEUTICALS INC | 2,198 | 80,686,000 | 4.69% | Put | |
| 5 | MERCK & CO | 12,648 | 74,459,000 | 4.33% | Call | |
| 6 | REGENERON PHARMACEUTICALS | 162,517 | 59,658,000 | 3.47% | ||
| 7 | SAREPTA THERAPEUTICS INC | 2,014,787 | 55,266,000 | 3.21% | ||
| 8 | AMGEN INC | 3,694 | 54,010,000 | 3.14% | Put | |
| 9 | SAREPTA THERAPEUTICS INC | 19,251 | 52,805,000 | 3.07% | Put | |
| 10 | BRISTOL MYERS SQUIBB CO | 8,478 | 49,545,000 | 2.88% | Put | |
| 11 | HCA HOLDINGS INC | 6,491 | 48,046,000 | 2.79% | Call | |
| 12 | AMGEN INC | 252,795 | 36,961,000 | 2.15% | ||
| 13 | BRISTOL MYERS SQUIBB CO | 5,419 | 31,669,000 | 1.84% | Call | |
| 14 | TEVA PHARMACEUTICAL INDUSTRIES LTD | 8,638 | 31,313,000 | 1.82% | Call | |
| 15 | GILEAD SCIENCES INC | 4,317 | 30,914,000 | 1.80% | Call | |
| 16 | ELI LILLY & CO | 4,043 | 29,736,000 | 1.73% | Put | |
| 17 | SPDR S&P BIOTECH ETF | 4,623 | 27,364,000 | 1.59% | Put | |
| 18 | TESARO INC | 1,866 | 25,094,000 | 1.46% | Call | |
| 19 | EXPRESS SCRIPTS HOLDING CO | 2,897 | 19,928,000 | 1.16% | Call | |
| 20 | ALEXION PHARMACEUTICALS INC | 1,586 | 19,405,000 | 1.13% | Call | |
| 21 | ACADIA PHARMACEUTICALS INC | 6,470 | 18,659,000 | 1.09% | Call | |
| 22 | BRISTOL MYERS SQUIBB CO | 289,183 | 16,900,000 | 0.98% | ||
| 23 | MYLAN N.V. | 4,162 | 15,878,000 | 0.92% | Call | |
| 24 | UNITED THERAPEUTICS CORP | 1,100 | 15,777,000 | 0.92% | Put | |
| 25 | LILLY ELI & CO | 213,113 | 15,674,000 | 0.91% | ||
| 26 | ZOGENIX INC | 12,366 | 15,025,000 | 0.87% | Call | |
| 27 | CLOVIS ONCOLOGY INC | 3,378 | 15,005,000 | 0.87% | Call | |
| 28 | ABBVIE INC | 2,204 | 13,801,000 | 0.80% | Call | |
| 29 | ASTRAZENECA PLC | 4,753 | 12,985,000 | 0.76% | Call | |
| 30 | ACORDA THERAPEUTICS INC | 6,145 | 11,553,000 | 0.67% | Put | |
| 31 | HORIZON PHARMA PLC | 5,962 | 9,647,000 | 0.56% | Call | |
| 32 | ALKERMES PLC | 1,639 | 9,110,000 | 0.53% | Call | |
| 33 | RETROPHIN INC | 4,798 | 9,083,000 | 0.53% | Call | |
| 34 | EXPRESS SCRIPTS HOLDING CO | 1,191 | 8,193,000 | 0.48% | Put | |
| 35 | EXELIXIS INC | 5,392 | 8,039,000 | 0.47% | Put | |
| 36 | VERTEX PHARMACEUTICALS INC | 1,070 | 7,883,000 | 0.46% | Call | |
| 37 | ALNYLAM PHARMACEUTICALS INC | 2,056 | 7,698,000 | 0.45% | Put | |
| 38 | TESARO Inc | 563 | 7,571,000 | 0.44% | Put | |
| 39 | REGENERON PHARMACEUTICALS INC | 202 | 7,415,000 | 0.43% | Call | |
| 40 | ABBVIE INC | 1,178 | 7,377,000 | 0.43% | Put | |
| 41 | Axovant Sciences Ltd | 5,726 | 7,112,000 | 0.41% | Call | |
| 42 | ONCOBIOLOGICS INC | 2,238,470 | 6,738,000 | 0.39% | ||
| 43 | PUMA BIOTECHNOLOGY INC | 2,177 | 6,683,000 | 0.39% | Call | |
| 44 | PTC THERAPEUTICS INC | 5,940 | 6,481,000 | 0.38% | Call | |
| 45 | HUMANA INC | 291 | 5,937,000 | 0.35% | Call | |
| 46 | BIOGEN INC | 20,000 | 5,672,000 | 0.33% | ||
| 47 | HESS CORP | 902 | 5,619,000 | 0.33% | Call | |
| 48 | KITE PHARMA INC | 1,171 | 5,251,000 | 0.31% | Call | |
| 49 | PUMA BIOTECHNOLOGY INC | 1,699 | 5,216,000 | 0.30% | Put | |
| 50 | MOTIF BIO PLC | 847,826 | 5,121,000 | 0.30% |
Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001144204-17-008083, filed 2017.02.14).
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
