| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | ELI LILLY & CO | 28,962 | 208,555,000 | 10.43% | Call | |
| 2 | SPDR S&P 500 ETF TR PUT | 10,176 | 188,635,000 | 9.44% | Put | |
| 3 | IMMUNOMEDICS INC | 2,680,000 | 182,240,000 | 9.12% | PRN | |
| 4 | BIOGEN INC | 6,663 | 173,451,000 | 8.68% | Call | |
| 5 | ISHARES TR | 17,673 | 162,342,000 | 8.12% | Put | |
| 6 | ABBVIE INC | 13,966 | 79,774,000 | 3.99% | Call | |
| 7 | GILEAD SCIENCES INC | 8,440 | 77,530,000 | 3.88% | Call | |
| 8 | JOHNSON & JOHNSON | 6,374 | 68,967,000 | 3.45% | Call | |
| 9 | HCA HOLDINGS INC | 6,798 | 53,058,000 | 2.65% | Call | |
| 10 | AMGEN INC | 3,441 | 51,591,000 | 2.58% | Put | |
| 11 | ELI LILLY & CO | 4,803 | 34,586,000 | 1.73% | Put | |
| 12 | MEDICINES CO | 9,501 | 30,185,000 | 1.51% | Call | |
| 13 | SPDR S&P BIOTECH ETF | 5,337 | 27,571,000 | 1.38% | Put | |
| 14 | BIOGEN INC | 1,052 | 27,386,000 | 1.37% | Put | |
| 15 | SPDR S&P 500 ETF TR | 108,899 | 22,385,000 | 1.12% | ||
| 16 | JOHNSON & JOHNSON | 2,061 | 22,300,000 | 1.12% | Put | |
| 17 | EDWARDS LIFESCIENCES CORP | 2,477 | 21,850,000 | 1.09% | Call | |
| 18 | AMGEN INC | 143,486 | 21,513,000 | 1.08% | ||
| 19 | REGENERON PHARMACEUTICALS INC | 588 | 21,194,000 | 1.06% | Put | |
| 20 | EDWARDS LIFESCIENCES CORP | 2,201 | 19,415,000 | 0.97% | Put | |
| 21 | SAREPTA THERAPEUTICS INC | 8,824 | 17,224,000 | 0.86% | Put | |
| 22 | CYTORI THERAPEUTIC INC | 7,305,690 | 14,310,000 | 0.72% | ||
| 23 | REGENERON PHARMACEUTICALS | 39,027 | 14,067,000 | 0.70% | ||
| 24 | SAREPTA THERAPEUTICS INC | 505,937 | 9,876,000 | 0.49% | ||
| 25 | BIOGEN INC | 37,077 | 9,652,000 | 0.48% | ||
| 26 | GLOBAL BLOOD THERAPEUTICS IN | 5,627 | 8,924,000 | 0.45% | Call | |
| 27 | ABBVIE INC | 1,546 | 8,831,000 | 0.44% | Put | |
| 28 | ACORDA THERAPEUTICS INC | 9,600,000 | 8,580,000 | 0.43% | PRN | |
| 29 | RETROPHIN INC | 6,251 | 8,539,000 | 0.43% | Put | |
| 30 | UNITED THERAPEUTICS CORP | 750 | 8,357,000 | 0.42% | Call | |
| 31 | REGULUS THERAPEUTICS INC | 11,703 | 8,110,000 | 0.41% | Call | |
| 32 | EXPRESS SCRIPTS HOLDING CO | 1,064 | 7,309,000 | 0.37% | Put | |
| 33 | LINKEDIN CORP | 579 | 6,621,000 | 0.33% | Call | |
| 34 | PORTOLA PHARMACEUTICALS INC | 3,221 | 6,571,000 | 0.33% | Call | |
| 35 | GW PHARMACEUTICALS PLC | 908 | 6,551,000 | 0.33% | Put | |
| 36 | ANACOR PHARMACEUTICALS INC | 1,214 | 6,489,000 | 0.32% | Call | |
| 37 | DEPOMED INC | 4,208 | 5,862,000 | 0.29% | Call | |
| 38 | BIOMARIN PHARMACEUTICAL INC | 5,000,000 | 5,794,000 | 0.29% | PRN | |
| 39 | TENAX THERAPEUTICS INC COM | 2,771,109 | 5,681,000 | 0.28% | ||
| 40 | BLUEPRINT MEDICINES CORP | 3,000 | 5,415,000 | 0.27% | Call | |
| 41 | ACADIA PHARMACEUTICALS INC | 1,840 | 5,145,000 | 0.26% | Call | |
| 42 | ARBUTUS BIOPHARMA | 1,197,338 | 4,945,000 | 0.25% | ||
| 43 | RETROPHIN INC | 3,617 | 4,941,000 | 0.25% | Call | |
| 44 | LEXICON PHARMACEUTICALS INC | 4,092 | 4,890,000 | 0.24% | Call | |
| 45 | NORTHWEST BIOTHERAPEUTICS INC | 3,317,519 | 4,844,000 | 0.24% | ||
| 46 | ALEXION PHARMACEUTICALS INC | 342 | 4,761,000 | 0.24% | Put | |
| 47 | TOKAI PHARMACEUTICALS INC | 812,200 | 4,556,000 | 0.23% | ||
| 48 | VERTEX PHARMACEUTICALS INC | 550 | 4,372,000 | 0.22% | Call | |
| 49 | REXAHN PHARMACEUTICALS INC | 13,212,254 | 4,361,000 | 0.22% | ||
| 50 | EIGER BIOPHARMACEUTICALS INC | 259,643 | 4,354,000 | 0.22% |
Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001144204-16-101848, filed 2016.05.13).
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
