| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | PRICE T ROWE ASSOCIATES INC /MD/ | 25,653,742 | 94,149,000 | 24.84% | ||
| 2 | FMR LLC | 12,198,200 | 44,768,000 | 11.81% | ||
| 3 | BlackRock Fund Advisors | 7,562,472 | 27,754,000 | 7.32% | ||
| 4 | STATE STREET CORP | 6,867,161 | 25,201,000 | 6.65% | ||
| 5 | BAKER BROS. ADVISORS LP | 5,790,139 | 21,250,000 | 5.61% | ||
| 6 | BlackRock Institutional Trust Company, N.A. | 4,761,941 | 17,476,000 | 4.61% | ||
| 7 | VANGUARD GROUP INC | 4,668,629 | 17,134,000 | 4.52% | ||
| 8 | TimesSquare Capital Management, LLC | 4,195,678 | 15,398,000 | 4.06% | ||
| 9 | MILLENNIUM MANAGEMENT LLC | 2,804,000 | 10,291,000 | 2.71% | Call | |
| 10 | WELLINGTON MANAGEMENT GROUP LLP | 2,596,734 | 9,530,000 | 2.51% | ||
| 11 | MILLENNIUM MANAGEMENT LLC | 2,375,613 | 8,718,000 | 2.30% | ||
| 12 | NORTHERN TRUST CORP | 1,932,308 | 7,091,000 | 1.87% | ||
| 13 | GOLDMAN SACHS GROUP INC | 1,553,682 | 5,702,000 | 1.50% | ||
| 14 | Artal Group S.A. | 1,300,000 | 4,771,000 | 1.26% | Call | |
| 15 | CREDIT SUISSE AG/ | 1,049,822 | 3,854,000 | 1.02% | ||
| 16 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 984,600 | 3,613,000 | 0.95% | Put | |
| 17 | Artal Group S.A. | 900,000 | 3,303,000 | 0.87% | ||
| 18 | GOLDMAN SACHS GROUP INC | 858,400 | 3,150,000 | 0.83% | Call | |
| 19 | Bank of New York Mellon Corp | 825,609 | 3,029,000 | 0.80% | ||
| 20 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 790,800 | 2,903,000 | 0.77% | Call | |
| 21 | GEODE CAPITAL MANAGEMENT, LLC | 771,892 | 2,832,000 | 0.75% | ||
| 22 | J. Goldman & Co LP | 700,000 | 2,569,000 | 0.68% | Call | |
| 23 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 666,465 | 2,446,000 | 0.65% | ||
| 24 | TIAA CREF INVESTMENT MANAGEMENT LLC | 656,712 | 2,410,000 | 0.64% | ||
| 25 | GOLDMAN SACHS GROUP INC | 628,500 | 2,307,000 | 0.61% | Put | |
| 26 | BARCLAYS PLC | 740,800 | 2,222,000 | 0.59% | Call | |
| 27 | BARCLAYS PLC | 711,936 | 2,136,000 | 0.56% | ||
| 28 | TD ASSET MANAGEMENT INC | 532,381 | 1,954,000 | 0.52% | ||
| 29 | CREDIT SUISSE AG/ | 466,300 | 1,711,000 | 0.45% | Call | |
| 30 | SUNTRUST BANKS INC | 406,653 | 1,490,000 | 0.39% | ||
| 31 | BlackRock Investment Management, LLC | 402,004 | 1,475,000 | 0.39% | ||
| 32 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 386,481 | 1,419,000 | 0.37% | ||
| 33 | CREDIT SUISSE AG/ | 369,400 | 1,356,000 | 0.36% | Put | |
| 34 | Allianz Asset Management GmbH | 359,530 | 1,319,000 | 0.35% | ||
| 35 | GROUP ONE TRADING LLC | 350,066 | 1,285,000 | 0.34% | ||
| 36 | Fiera Capital Corp | 345,000 | 1,266,000 | 0.33% | ||
| 37 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 338,700 | 1,209,000 | 0.32% | ||
| 38 | Rock Springs Capital Management LP | 300,000 | 1,101,000 | 0.29% | ||
| 39 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 263,760 | 968,000 | 0.26% | ||
| 40 | ProShare Advisors LLC | 263,519 | 967,000 | 0.26% | ||
| 41 | DEUTSCHE BANK AG\ | 261,202 | 958,000 | 0.25% | ||
| 42 | Iguana Healthcare Management, LLC | 250,000 | 918,000 | 0.24% | ||
| 43 | ALLIANCEBERNSTEIN L.P. | 240,300 | 882,000 | 0.23% | ||
| 44 | TEACHERS ADVISORS, LLC | 233,845 | 858,000 | 0.23% | ||
| 45 | HighTower Advisors, LLC | 185,295 | 680,000 | 0.18% | ||
| 46 | Swiss National Bank | 160,900 | 591,000 | 0.16% | ||
| 47 | AQR CAPITAL MANAGEMENT LLC | 159,000 | 584,000 | 0.15% | ||
| 48 | RHUMBLINE ADVISERS | 140,930 | 517,000 | 0.14% | ||
| 49 | J. Goldman & Co LP | 137,500 | 505,000 | 0.13% | Put | |
| 50 | UBS AG | 120,100 | 441,000 | 0.12% | Call |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
