| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | SEATTLE GENETICS INC | 20,739,426 | 944,887,000 | 12.01% | ||
| 2 | SYNAGEVA BIOPHARMA CORP | 10,648,182 | 883,480,000 | 11.23% | ||
| 3 | PHARMACYCLICS INC | 8,737,888 | 875,711,000 | 11.13% | ||
| 4 | INCYTE | 14,835,559 | 793,999,000 | 10.09% | ||
| 5 | ACADIA PHARMACEUTICALS INC COM | 20,481,442 | 498,313,000 | 6.33% | ||
| 6 | Salix Pharmaceuticals Inc 05/15/2015 2.750% | 219,440,000 | 491,957,000 | 6.25% | PRN | |
| 7 | GENOMIC HEALTH INC COM | 13,654,150 | 359,650,000 | 4.57% | ||
| 8 | Incyte Corporation | 274,500,000 | 350,417,000 | 4.45% | PRN | |
| 9 | Incyte Corporation | 259,000,000 | 326,745,000 | 4.15% | PRN | |
| 10 | INCYTE CORP SR NT CONV 4.750% 10/01/15 B/EDTD 03/30/10 0221 UBS FINANCIAL SERVICES INC. A/C MR06471 | 40,446,000 | 245,887,000 | 3.13% | PRN | |
| 11 | INTERMUNE INC | 4,324,843 | 144,752,000 | 1.84% | ||
| 12 | Auxilium Pharmaceuticals Inc | 97,990,000 | 128,796,000 | 1.64% | PRN | |
| 13 | BIOMARIN | 1,883,230 | 128,455,000 | 1.63% | ||
| 14 | XOMA CORP DEL | 23,057,572 | 120,130,000 | 1.53% | ||
| 15 | Intermune | 41,000,000 | 107,856,000 | 1.37% | PRN | |
| 16 | INTERCEPT PHARMACEUTICAL | 256,375 | 84,550,000 | 1.07% | ||
| 17 | BIOMARIN PHARMACEUTICAL INC | 22,898,000 | 77,127,000 | 0.98% | PRN | |
| 18 | HALOZYME THERAPEUTICS INC | 5,698,139 | 72,366,000 | 0.92% | ||
| 19 | VANDA PHARMACEUTICALS INC COM | 4,445,696 | 72,243,000 | 0.92% | ||
| 20 | GILEAD SCIENCES | 21,500,000 | 66,903,000 | 0.85% | PRN | |
| 21 | BIOCRYST PHARMACEUTICALS | 5,867,031 | 62,073,000 | 0.79% | ||
| 22 | Anacor Pharmaceuticals Inc | 3,095,318 | 61,937,000 | 0.79% | ||
| 23 | Medivation Inc 04/01/2017 2.625% | 39,500,000 | 56,288,000 | 0.72% | PRN | |
| 24 | REPROS THERAPEUTICS INC | 2,778,654 | 49,293,000 | 0.63% | ||
| 25 | Questcor | 717,745 | 46,603,000 | 0.59% | ||
| 26 | MIRATI THERAPEUTICS INC COM | 2,380,074 | 45,388,000 | 0.58% | ||
| 27 | DERMA SCIENCES INC COM PAR .01 | 3,537,137 | 44,851,000 | 0.57% | ||
| 28 | CERUS CORP | 8,455,306 | 40,585,000 | 0.52% | ||
| 29 | GILEAD SCIENCES INC | 556,108 | 39,406,000 | 0.50% | ||
| 30 | ACORDA THERAPEUTICS | 1,000,000 | 37,910,000 | 0.48% | ||
| 31 | CHELSEA THERAPEUTICS INTL LT | 6,760,394 | 37,317,000 | 0.47% | ||
| 32 | CLOVIS ONCOLOGY INC | 529,990 | 36,712,000 | 0.47% | ||
| 33 | Intermune | 16,860,000 | 30,590,000 | 0.39% | PRN | |
| 34 | HERON THERAPEUTICS INC | 2,167,784 | 30,153,000 | 0.38% | ||
| 35 | SALIX PHARMACEUTICALS INC | 15,000,000 | 25,289,000 | 0.32% | PRN | |
| 36 | AEGERION PHARMACEUTICALS INC | 513,922 | 23,702,000 | 0.30% | ||
| 37 | DYAX CORP COM CVR | 2,531,766 | 22,735,000 | 0.29% | ||
| 38 | AVANIR PHARMACEUTICALS INC CL | 5,790,139 | 21,250,000 | 0.27% | ||
| 39 | XENOPORT INC | 4,034,112 | 20,856,000 | 0.27% | ||
| 40 | PROGENICS PHARMACEUTICALS IN | 4,449,797 | 18,200,000 | 0.23% | ||
| 41 | Aquinox Pharmaceuticals Inc | 1,211,851 | 15,427,000 | 0.20% | ||
| 42 | TG THERAPEUTICS INC COM | 2,160,965 | 14,911,000 | 0.19% | ||
| 43 | BIOMARIN PHARMACEUTICAL INC | 12,500,000 | 13,699,000 | 0.17% | PRN | |
| 44 | KYTHERA BIOPHARMACEUTICALS I | 311,255 | 12,375,000 | 0.16% | ||
| 45 | Arrowhead Pharma Inc | 732,062 | 12,020,000 | 0.15% | ||
| 46 | INSMED INC COM PAR .01 | 554,050 | 10,549,000 | 0.13% | ||
| 47 | Tekmira Pharmaceuticals Corp. | 484,156 | 10,405,000 | 0.13% | ||
| 48 | SANGAMO BIOSCIENCES INCORPORATED | 522,764 | 9,452,000 | 0.12% | ||
| 49 | SYNERGY PHARMACEUTICALS DEL COM NEW | 1,758,271 | 9,336,000 | 0.12% | ||
| 50 | OMEROS CORP | 753,804 | 9,098,000 | 0.12% |
Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001144204-14-031196, filed 2014.05.15).
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
