| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | JPMORGAN CHASE & CO | 2,437,979 | 6,948,000 | 19.91% | ||
| 2 | Broadfin Capital, LLC | 1,122,133 | 3,198,000 | 9.16% | ||
| 3 | BAKER BROS. ADVISORS LP | 1,106,910 | 3,155,000 | 9.04% | ||
| 4 | DAFNA Capital Management LLC | 729,781 | 2,080,000 | 5.96% | ||
| 5 | BLACKROCK ADVISORS LLC | 708,694 | 2,020,000 | 5.79% | ||
| 6 | Visium Asset Management, LP | 600,000 | 1,710,000 | 4.90% | ||
| 7 | FMR LLC | 473,400 | 1,349,000 | 3.87% | ||
| 8 | BVF INC/IL | 435,900 | 1,242,000 | 3.56% | ||
| 9 | BlackRock Institutional Trust Company, N.A. | 396,217 | 1,129,000 | 3.23% | ||
| 10 | GABELLI & Co INVESTMENT ADVISERS, INC. | 360,668 | 1,028,000 | 2.95% | ||
| 11 | RENAISSANCE TECHNOLOGIES LLC | 321,105 | 915,000 | 2.62% | ||
| 12 | PERCEPTIVE ADVISORS LLC | 253,400 | 722,000 | 2.07% | ||
| 13 | TOWERVIEW LLC | 225,000 | 641,000 | 1.84% | ||
| 14 | GOLDMAN SACHS GROUP INC | 188,970 | 539,000 | 1.54% | ||
| 15 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 181,100 | 516,000 | 1.48% | Put | |
| 16 | VANGUARD GROUP INC | 179,977 | 513,000 | 1.47% | ||
| 17 | DIMENSIONAL FUND ADVISORS LP | 169,888 | 484,000 | 1.39% | ||
| 18 | DEUTSCHE BANK AG\ | 162,063 | 460,000 | 1.32% | ||
| 19 | GEODE CAPITAL MANAGEMENT, LLC | 159,763 | 455,000 | 1.30% | ||
| 20 | BlackRock Group LTD | 158,400 | 451,000 | 1.29% | ||
| 21 | Dominick & Dominick LLC | 146,016 | 416,000 | 1.19% | ||
| 22 | Healthcare Value Capital, LLC | 145,507 | 415,000 | 1.19% | ||
| 23 | MORGAN STANLEY | 135,611 | 387,000 | 1.11% | ||
| 24 | BlackRock Finance, Inc. | 132,900 | 379,000 | 1.09% | ||
| 25 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 119,699 | 341,000 | 0.98% | ||
| 26 | SHEPHERD KAPLAN KROCHUK, LLC | 119,822 | 341,000 | 0.98% | ||
| 27 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 116,150 | 331,000 | 0.95% | ||
| 28 | BAILARD, INC. | 115,000 | 328,000 | 0.94% | ||
| 29 | BlackRock Fund Advisors | 92,107 | 263,000 | 0.75% | ||
| 30 | KNOTT DAVID M | 88,100 | 251,085 | 0.72% | ||
| 31 | Spark Investment Management LLC | 83,700 | 236,000 | 0.68% | ||
| 32 | BOGLE INVESTMENT MANAGEMENT L P /DE/ | 82,531 | 235,000 | 0.67% | ||
| 33 | TFS CAPITAL LLC | 68,964 | 197,000 | 0.56% | ||
| 34 | NORTHERN TRUST CORP | 66,813 | 191,000 | 0.55% | ||
| 35 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 62,624 | 178,000 | 0.51% | ||
| 36 | A.R.T. Advisors, LLC | 47,709 | 135,000 | 0.39% | ||
| 37 | JANE STREET GROUP, LLC | 38,202 | 108,000 | 0.31% | ||
| 38 | STATE STREET CORP | 28,473 | 80,000 | 0.23% | ||
| 39 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 26,016 | 75,000 | 0.21% | ||
| 40 | GSA CAPITAL PARTNERS LLP | 24,700 | 70,000 | 0.20% | ||
| 41 | GABELLI FUNDS LLC | 22,761 | 65,000 | 0.19% | ||
| 42 | Virtu KCG Holdings LLC | 19,367 | 55,000 | 0.16% | ||
| 43 | Quotient Investors, LLC | 17,100 | 49,000 | 0.14% | ||
| 44 | PDT Partners, LLC | 14,000 | 40,000 | 0.11% | ||
| 45 | GUGGENHEIM CAPITAL LLC | 12,937 | 37,000 | 0.11% | ||
| 46 | Bank of New York Mellon Corp | 12,302 | 35,000 | 0.10% | ||
| 47 | CREDIT SUISSE AG/ | 11,841 | 33,000 | 0.09% | ||
| 48 | MILLENNIUM MANAGEMENT LLC | 11,111 | 32,000 | 0.09% | ||
| 49 | BlackRock Investment Management, LLC | 5,592 | 16,000 | 0.05% | ||
| 50 | BARCLAYS PLC | 4,403 | 9,000 | 0.03% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
