| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | BIOGEN INC | 439,428 | 149,164,000 | 6.69% | ||
| 2 | AMGEN INC | 894,473 | 142,481,000 | 6.39% | ||
| 3 | CELGENE CORP | 1,134,258 | 126,878,000 | 5.69% | ||
| 4 | BIOMARIN | 1,253,243 | 113,293,000 | 5.08% | ||
| 5 | INCYTE | 1,332,814 | 97,442,000 | 4.37% | ||
| 6 | Mylan Inc | 1,519,368 | 85,647,000 | 3.84% | ||
| 7 | TEVA PHARMACEUTICAL INDS LTD | 1,380,888 | 79,415,000 | 3.56% | ||
| 8 | REGENERON PHARMACEUTICALS | 185,685 | 76,177,000 | 3.42% | ||
| 9 | ALEXION PHARMACEUTIC | 385,624 | 71,352,000 | 3.20% | ||
| 10 | ALLERGAN PLC | 256,850 | 66,116,000 | 2.97% | ||
| 11 | THERMO FISHER SCIENTIFIC INC | 520,686 | 65,237,000 | 2.93% | ||
| 12 | GILEAD SCIENCES INC | 684,307 | 64,503,000 | 2.89% | ||
| 13 | PTC THERAPEUTICS INC | 1,135,130 | 58,766,000 | 2.64% | ||
| 14 | NPS Pharmaceuticals, Inc. | 1,623,073 | 58,057,000 | 2.60% | ||
| 15 | SHIRE PLC | 236,124 | 50,186,000 | 2.25% | ||
| 16 | KERYX BIOPHARMACEUTICALS INCORPORATED | 3,257,358 | 46,092,000 | 2.07% | ||
| 17 | MALLINCKRODT PUB LTD CO SHS | 400,664 | 39,678,000 | 1.78% | ||
| 18 | AMICUS THERAPEUTICS INC | 4,765,498 | 39,649,000 | 1.78% | ||
| 19 | PERRIGO CO PLC | 232,068 | 38,792,000 | 1.74% | ||
| 20 | DR REDDYS LABS LTD | 762,969 | 38,492,000 | 1.73% | ||
| 21 | PFIZER INC | 1,209,914 | 37,689,000 | 1.69% | ||
| 22 | HALOZYME THERAPEUTICS INC | 3,724,351 | 35,940,000 | 1.61% | ||
| 23 | MEDIVATION INC | 356,806 | 35,541,000 | 1.59% | ||
| 24 | SEATTLE GENETICS INC | 1,104,075 | 35,474,000 | 1.59% | ||
| 25 | ONCOMED PHARMACEUTICALS INC | 1,598,293 | 34,779,000 | 1.56% | ||
| 26 | Allergan plc | 162,750 | 34,599,000 | 1.55% | ||
| 27 | SYNAGEVA BIOPHARMA CORP | 363,884 | 33,765,000 | 1.51% | ||
| 28 | PORTOLA PHARMACEUTICALS INC | 1,120,379 | 31,729,000 | 1.42% | ||
| 29 | ACHILLION PHARMACEUTICALS INC COM | 2,373,810 | 29,079,000 | 1.30% | ||
| 30 | INTERCEPT PHARMACEUTICAL | 181,847 | 28,368,000 | 1.27% | ||
| 31 | ACCELERON PHARMA | 713,995 | 27,817,000 | 1.25% | ||
| 32 | VERTEX PHARMACEUT | 212,250 | 25,215,000 | 1.13% | ||
| 33 | RELYPSA INC | 811,330 | 24,989,000 | 1.12% | ||
| 34 | CLOVIS ONCOLOGY INC | 423,452 | 23,713,000 | 1.06% | ||
| 35 | MEDTRONIC INC | 310,025 | 22,384,000 | 1.00% | ||
| 36 | UNITED THERAPEUTICS | 162,880 | 21,091,000 | 0.95% | ||
| 37 | SAGENT PHARMACEUTICALS INC | 833,861 | 20,938,000 | 0.94% | ||
| 38 | KARYOPHARM THERAPEUTICS INC COM | 529,920 | 19,835,000 | 0.89% | ||
| 39 | ABBOTT LABS | 405,410 | 18,252,000 | 0.82% | ||
| 40 | INTUITIVE SURGICAL INC | 34,416 | 18,204,000 | 0.82% | ||
| 41 | Momenta Pharmaceuticals Inc | 1,459,603 | 17,574,000 | 0.79% | ||
| 42 | ALIGN TECHNOLOGY INC | 309,031 | 17,278,000 | 0.77% | ||
| 43 | DEXCOM | 286,065 | 15,748,000 | 0.71% | ||
| 44 | AKORN INC | 434,343 | 15,723,000 | 0.71% | ||
| 45 | NXSTAGE MED INC COM | 807,012 | 14,470,000 | 0.65% | ||
| 46 | Heartware International, Inc. | 168,525 | 12,375,000 | 0.56% | ||
| 47 | HCA HOLDINGS INC | 144,002 | 10,568,000 | 0.47% | ||
| 48 | NOVO-NORDISK A S | 185,285 | 7,841,000 | 0.35% | ||
| 49 | AMPHASTAR PHARMACEUTICALS IN COM | 660,232 | 7,665,000 | 0.34% | ||
| 50 | CymaBay Therapeutics | 708,585 | 6,965,000 | 0.31% |
Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001104659-15-010210, filed 2015.02.13).
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
