| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | VANGUARD GROUP INC | 2,747,239 | 88,735,000 | 6.60% | ||
| 2 | PRICE T ROWE ASSOCIATES INC /MD/ | 2,579,501 | 83,318,000 | 6.20% | ||
| 3 | BlackRock Fund Advisors | 1,921,554 | 62,066,000 | 4.62% | ||
| 4 | FMR LLC | 1,754,619 | 56,674,000 | 4.22% | ||
| 5 | WESTFIELD CAPITAL MANAGEMENT CO LP | 1,603,681 | 51,799,000 | 3.86% | ||
| 6 | HealthCor Management, L.P. | 1,575,000 | 50,873,000 | 3.79% | ||
| 7 | GILDER GAGNON HOWE & CO LLC | 1,226,278 | 39,609,000 | 2.95% | ||
| 8 | DARUMA CAPITAL MANAGEMENT LLC | 1,219,642 | 39,394,000 | 2.93% | ||
| 9 | PFM Health Sciences, LP | 1,160,975 | 37,499,000 | 2.79% | ||
| 10 | Clearbridge Investments, LLC | 1,085,310 | 35,056,000 | 2.61% | ||
| 11 | STATE STREET CORP | 1,078,693 | 34,834,000 | 2.59% | ||
| 12 | MILLENNIUM MANAGEMENT LLC | 1,053,151 | 34,017,000 | 2.53% | ||
| 13 | MACQUARIE GROUP LTD | 1,007,449 | 32,541,000 | 2.42% | ||
| 14 | BlackRock Institutional Trust Company, N.A. | 953,623 | 30,802,000 | 2.29% | ||
| 15 | PointState Capital LP | 844,000 | 27,261,000 | 2.03% | ||
| 16 | Standard Investments LLC | 775,388 | 25,045,000 | 1.86% | ||
| 17 | SCHRODER INVESTMENT MANAGEMENT GROUP | 754,022 | 24,355,000 | 1.81% | ||
| 18 | Stephens Investment Management Group LLC | 751,224 | 24,265,000 | 1.81% | ||
| 19 | Rock Springs Capital Management LP | 713,000 | 23,030,000 | 1.71% | ||
| 20 | Invesco Ltd. | 673,737 | 21,761,000 | 1.62% | ||
| 21 | Granahan Investment Management, LLC | 636,480 | 20,558,000 | 1.53% | ||
| 22 | Consonance Capital Management LP | 631,805 | 20,407,000 | 1.52% | ||
| 23 | WADDELL & REED FINANCIAL INC | 561,680 | 18,142,000 | 1.35% | ||
| 24 | Alyeska Investment Group, L.P. | 543,110 | 17,542,000 | 1.31% | ||
| 25 | VOYA INVESTMENT MANAGEMENT LLC | 539,641 | 17,430,000 | 1.30% | ||
| 26 | OAK RIDGE INVESTMENTS LLC | 534,924 | 17,278,000 | 1.29% | ||
| 27 | BANK OF NOVA SCOTIA | 498,000 | 16,085,000 | 1.20% | ||
| 28 | DEUTSCHE BANK AG\ | 460,059 | 14,858,000 | 1.11% | ||
| 29 | NORTHERN TRUST CORP | 459,304 | 14,835,000 | 1.10% | ||
| 30 | Elk Creek Partners, LLC | 447,857 | 14,466,000 | 1.08% | ||
| 31 | BANK OF AMERICA CORP /DE/ | 433,193 | 13,992,000 | 1.04% | ||
| 32 | NORGES BANK | 410,467 | 13,258,000 | 0.99% | ||
| 33 | ARMISTICE CAPITAL, LLC | 400,000 | 12,920,000 | 0.96% | ||
| 34 | PEREGRINE CAPITAL MANAGEMENT INC /MN/ | 368,169 | 11,892,000 | 0.89% | ||
| 35 | GEODE CAPITAL MANAGEMENT, LLC | 348,530 | 11,257,000 | 0.84% | ||
| 36 | ROYAL BANK OF CANADA | 334,227 | 10,796,000 | 0.80% | ||
| 37 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 326,500 | 10,546,000 | 0.78% | Put | |
| 38 | TAMARACK ADVISERS, LP | 273,000 | 8,818,000 | 0.66% | ||
| 39 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 264,726 | 8,551,000 | 0.64% | ||
| 40 | ASCEND CAPITAL, LLC | 258,557 | 8,351,000 | 0.62% | ||
| 41 | FOLGER HILL ASSET MANAGEMENT LP | 250,000 | 8,075,000 | 0.60% | Call | |
| 42 | TWO SIGMA INVESTMENTS, LP | 238,916 | 7,717,000 | 0.57% | ||
| 43 | PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO | 223,453 | 7,218,000 | 0.54% | ||
| 44 | BAILLIE GIFFORD & CO | 213,600 | 6,899,000 | 0.51% | ||
| 45 | JPMORGAN CHASE & CO | 203,563 | 6,575,000 | 0.49% | ||
| 46 | Bank of New York Mellon Corp | 198,069 | 6,398,000 | 0.48% | ||
| 47 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 187,200 | 6,047,000 | 0.45% | Call | |
| 48 | BARCLAYS PLC | 186,800 | 6,033,000 | 0.45% | Put | |
| 49 | BALYASNY ASSET MANAGEMENT L.P. | 175,259 | 5,661,000 | 0.42% | ||
| 50 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 170,700 | 5,513,000 | 0.41% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
