| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 4,227,232 | 237,824,000 | 14.75% | ||
| 2 | ALLIANCEBERNSTEIN L.P. | 1,816,620 | 102,203,000 | 6.34% | ||
| 3 | SENZAR ASSET MANAGEMENT, LLC | 1,483,730 | 83,474,650 | 5.18% | ||
| 4 | FRANKLIN RESOURCES INC | 1,457,000 | 81,970,000 | 5.08% | ||
| 5 | WELLS FARGO & COMPANY/MN | 1,392,314 | 78,333,000 | 4.86% | ||
| 6 | VANGUARD GROUP INC | 1,388,631 | 78,125,000 | 4.85% | ||
| 7 | COLUMBUS CIRCLE INVESTORS | 895,019 | 50,354,000 | 3.12% | ||
| 8 | JENNISON ASSOCIATES LLC | 886,667 | 49,884,000 | 3.09% | ||
| 9 | JPMORGAN CHASE & CO | 852,758 | 47,976,000 | 2.98% | ||
| 10 | Broadfin Capital, LLC | 667,907 | 37,576,000 | 2.33% | ||
| 11 | NEA Management Company, LLC | 660,428 | 37,156,000 | 2.30% | ||
| 12 | CITADEL ADVISORS LLC | 572,008 | 32,181,000 | 2.00% | ||
| 13 | Artisan Partners Limited Partnership | 571,120 | 32,131,000 | 1.99% | ||
| 14 | OAK RIDGE INVESTMENTS LLC | 544,590 | 30,639,000 | 1.90% | ||
| 15 | LORD, ABBETT & CO. LLC | 543,376 | 30,571,000 | 1.90% | ||
| 16 | Cormorant Asset Management, LP | 485,386 | 27,308,000 | 1.69% | ||
| 17 | Point72 Asset Management, L.P. | 462,100 | 25,998,000 | 1.61% | ||
| 18 | BlackRock Fund Advisors | 445,266 | 25,051,000 | 1.55% | ||
| 19 | MILLENNIUM MANAGEMENT LLC | 444,201 | 24,991,000 | 1.55% | ||
| 20 | HealthCor Management, L.P. | 430,877 | 24,241,000 | 1.50% | ||
| 21 | WADDELL & REED FINANCIAL INC | 423,800 | 23,843,000 | 1.48% | ||
| 22 | ArrowMark Colorado Holdings LLC | 401,669 | 22,598,000 | 1.40% | ||
| 23 | GOLDMAN SACHS GROUP INC | 380,100 | 21,384,000 | 1.33% | Call | |
| 24 | BlackRock Institutional Trust Company, N.A. | 359,374 | 20,218,000 | 1.25% | ||
| 25 | Visium Asset Management, LP | 358,390 | 20,163,000 | 1.25% | ||
| 26 | PERCEPTIVE ADVISORS LLC | 348,600 | 19,612,000 | 1.22% | ||
| 27 | KORNITZER CAPITAL MANAGEMENT INC /KS | 340,093 | 19,134,000 | 1.19% | ||
| 28 | Broadfin Capital, LLC | 300,000 | 16,878,000 | 1.05% | Call | |
| 29 | STATE STREET CORP | 280,583 | 15,786,000 | 0.98% | ||
| 30 | Cupps Capital Management, LLC | 269,108 | 15,140,000 | 0.94% | ||
| 31 | FEDERATED HERMES, INC. | 268,900 | 15,128,000 | 0.94% | ||
| 32 | ROYAL BANK OF CANADA | 249,246 | 14,022,000 | 0.87% | ||
| 33 | EverPoint Asset Management, LLC | 230,000 | 12,940,000 | 0.80% | ||
| 34 | Neuberger Berman Group LLC | 218,410 | 12,288,000 | 0.76% | ||
| 35 | NEXT CENTURY GROWTH INVESTORS LLC | 215,317 | 12,113,000 | 0.75% | ||
| 36 | NORTHERN TRUST CORP | 201,188 | 11,318,000 | 0.70% | ||
| 37 | MPM ASSET MANAGEMENT LLC | 150,000 | 8,439,000 | 0.52% | ||
| 38 | GOLDMAN SACHS GROUP INC | 141,368 | 7,953,000 | 0.49% | ||
| 39 | Bank of New York Mellon Corp | 136,261 | 7,666,000 | 0.48% | ||
| 40 | Redmile Group, LLC | 130,571 | 7,346,000 | 0.46% | ||
| 41 | PRINCIPAL FINANCIAL GROUP INC | 129,169 | 7,267,000 | 0.45% | ||
| 42 | DEUTSCHE BANK AG\ | 113,669 | 6,393,000 | 0.40% | ||
| 43 | Nationwide Fund Advisors | 110,334 | 6,219,000 | 0.39% | ||
| 44 | GOLDMAN SACHS GROUP INC | 110,100 | 6,194,000 | 0.38% | Put | |
| 45 | HIGHLAND CAPITAL MANAGEMENT LP | 109,270 | 6,147,000 | 0.38% | ||
| 46 | THRIVENT FINANCIAL FOR LUTHERANS | 107,800 | 6,065,000 | 0.38% | ||
| 47 | NEW YORK STATE COMMON RETIREMENT FUND | 106,692 | 6,002,000 | 0.37% | ||
| 48 | PERCEPTIVE ADVISORS LLC | 100,000 | 5,626,000 | 0.35% | Call | |
| 49 | Jefferies Group LLC | 90,300 | 5,080,000 | 0.32% | Call | |
| 50 | GEODE CAPITAL MANAGEMENT, LLC | 89,667 | 5,044,000 | 0.31% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
