| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 1,679,062 | 90,250,000 | 8.48% | ||
| 2 | Novo Holdings A/S | 1,525,704 | 82,007,000 | 7.71% | ||
| 3 | ALLIANCEBERNSTEIN L.P. | 1,324,674 | 71,201,000 | 6.69% | ||
| 4 | COLUMBUS CIRCLE INVESTORS | 1,065,279 | 57,259,000 | 5.38% | ||
| 5 | SENZAR ASSET MANAGEMENT, LLC | 1,006,479 | 54,098,000 | 5.09% | ||
| 6 | NEA Management Company, LLC | 993,428 | 53,397,000 | 5.02% | ||
| 7 | VANGUARD GROUP INC | 943,829 | 50,731,000 | 4.77% | ||
| 8 | JPMORGAN CHASE & CO | 819,479 | 44,047,000 | 4.14% | ||
| 9 | PERCEPTIVE ADVISORS LLC | 798,959 | 42,944,000 | 4.04% | ||
| 10 | FRANKLIN RESOURCES INC | 735,261 | 39,521,000 | 3.72% | ||
| 11 | KORNITZER CAPITAL MANAGEMENT INC /KS | 678,515 | 36,470,000 | 3.43% | ||
| 12 | LORD, ABBETT & CO. LLC | 588,667 | 31,641,000 | 2.97% | ||
| 13 | Broadfin Capital, LLC | 419,559 | 22,551,000 | 2.12% | ||
| 14 | BlackRock Fund Advisors | 415,274 | 22,321,000 | 2.10% | ||
| 15 | WELLS FARGO & COMPANY/MN | 407,605 | 21,909,000 | 2.06% | ||
| 16 | OAK RIDGE INVESTMENTS LLC | 395,311 | 21,248,000 | 2.00% | ||
| 17 | MPM ASSET MANAGEMENT LLC | 356,704 | 19,173,000 | 1.80% | ||
| 18 | Point72 Asset Management, L.P. | 314,116 | 16,884,000 | 1.59% | ||
| 19 | Cupps Capital Management, LLC | 309,217 | 16,620,000 | 1.56% | ||
| 20 | NEXT CENTURY GROWTH INVESTORS LLC | 305,341 | 16,412,000 | 1.54% | ||
| 21 | BlackRock Institutional Trust Company, N.A. | 265,426 | 14,267,000 | 1.34% | ||
| 22 | Visium Asset Management, LP | 250,300 | 13,454,000 | 1.26% | ||
| 23 | Cormorant Asset Management, LP | 208,500 | 11,207,000 | 1.05% | ||
| 24 | STATE STREET CORP | 194,022 | 10,432,000 | 0.98% | ||
| 25 | GLG LLC | 190,101 | 10,218,000 | 0.96% | ||
| 26 | HIGHLAND CAPITAL MANAGEMENT LP | 181,886 | 9,776,000 | 0.92% | ||
| 27 | Granite Point Capital Management, L.P. | 166,450 | 8,947,000 | 0.84% | ||
| 28 | MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 165,775 | 8,910,407 | 0.84% | ||
| 29 | CASTLEARK MANAGEMENT LLC | 137,490 | 7,390,000 | 0.69% | ||
| 30 | JENNISON ASSOCIATES LLC | 136,760 | 7,351,000 | 0.69% | ||
| 31 | MORGAN STANLEY | 133,963 | 7,201,000 | 0.68% | ||
| 32 | Bank of New York Mellon Corp | 130,709 | 7,026,000 | 0.66% | ||
| 33 | HAMILTON LANE ADVISORS LLC | 129,506 | 6,961,000 | 0.65% | ||
| 34 | Pier Capital, LLC | 129,343 | 6,952,000 | 0.65% | ||
| 35 | DRIEHAUS CAPITAL MANAGEMENT LLC | 128,376 | 6,900,000 | 0.65% | ||
| 36 | PRINCIPAL FINANCIAL GROUP INC | 123,484 | 6,637,000 | 0.62% | ||
| 37 | RENAISSANCE TECHNOLOGIES LLC | 119,600 | 6,429,000 | 0.60% | ||
| 38 | RUSSELL FRANK CO/ | 106,394 | 5,719,000 | 0.54% | ||
| 39 | NORTHERN TRUST CORP | 103,029 | 5,538,000 | 0.52% | ||
| 40 | MONASHEE INVESTMENT MANAGEMENT LLC | 100,000 | 5,375,000 | 0.51% | PRN | |
| 41 | Informed Momentum Co LLC | 96,829 | 5,205,000 | 0.49% | ||
| 42 | BARCLAYS PLC | 85,000 | 4,505,000 | 0.42% | Put | |
| 43 | GEODE CAPITAL MANAGEMENT, LLC | 81,228 | 4,366,000 | 0.41% | ||
| 44 | LAZARD ASSET MANAGEMENT LLC | 74,125 | 3,984,000 | 0.37% | ||
| 45 | WADDELL & REED FINANCIAL INC | 71,800 | 3,859,000 | 0.36% | ||
| 46 | Jasper Ridge Partners, L.P. | 67,378 | 3,622,000 | 0.34% | ||
| 47 | AMERICAN CENTURY COMPANIES INC | 65,688 | 3,531,000 | 0.33% | ||
| 48 | Forward Management, LLC | 73,033 | 3,450,000 | 0.32% | ||
| 49 | TIAA CREF INVESTMENT MANAGEMENT LLC | 59,400 | 3,193,000 | 0.30% | ||
| 50 | DEUTSCHE BANK AG\ | 57,158 | 3,071,000 | 0.29% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
