| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Third Security, LLC | 2,690,570 | 29,596,000 | 48.64% | ||
| 2 | FMR LLC | 1,875,331 | 20,629,000 | 33.90% | ||
| 3 | Palo Alto Investors LP | 454,545 | 5,000,000 | 8.22% | ||
| 4 | TURNER INVESTMENTS LLC | 233,940 | 2,573,000 | 4.23% | ||
| 5 | ACUTA CAPITAL PARTNERS, LLC | 136,804 | 1,505,000 | 2.47% | ||
| 6 | SABBY MANAGEMENT, LLC | 50,367 | 554,000 | 0.91% | ||
| 7 | MILLENNIUM MANAGEMENT LLC | 30,000 | 330,000 | 0.54% | ||
| 8 | GOLDMAN SACHS GROUP INC | 29,546 | 325,000 | 0.53% | ||
| 9 | OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 25,000 | 275,000 | 0.45% | ||
| 10 | MORGAN STANLEY | 2,950 | 32,000 | 0.05% | ||
| 11 | UBS Group AG | 1,046 | 12,000 | 0.02% | ||
| 12 | JBF Capital, Inc. | 1,000 | 11,000 | 0.02% | ||
| 13 | CITIGROUP INC | 675 | 8,000 | 0.01% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.