| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Third Security, LLC | 2,690,570 | 26,879,000 | 50.36% | ||
| 2 | FMR LLC | 1,913,520 | 19,116,000 | 35.81% | ||
| 3 | Palo Alto Investors LP | 454,545 | 4,541,000 | 8.51% | ||
| 4 | ACUTA CAPITAL PARTNERS, LLC | 123,249 | 1,231,000 | 2.31% | ||
| 5 | GOLDMAN SACHS GROUP INC | 42,198 | 422,000 | 0.79% | ||
| 6 | TURNER INVESTMENTS LLC | 33,530 | 335,000 | 0.63% | ||
| 7 | MILLENNIUM MANAGEMENT LLC | 30,930 | 309,000 | 0.58% | ||
| 8 | SABBY MANAGEMENT, LLC | 27,505 | 275,000 | 0.52% | ||
| 9 | BANK OF AMERICA CORP /DE/ | 11,236 | 112,000 | 0.21% | ||
| 10 | BlackRock Fund Advisors | 8,874 | 89,000 | 0.17% | ||
| 11 | CITIGROUP INC | 3,200 | 32,000 | 0.06% | ||
| 12 | MORGAN STANLEY | 1,950 | 19,000 | 0.04% | ||
| 13 | JBF Capital, Inc. | 1,000 | 10,000 | 0.02% | ||
| 14 | BlackRock Investment Management, LLC | 607 | 6,000 | 0.01% | ||
| 15 | UBS Group AG | 15 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.