| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Third Security, LLC | 2,690,570 | 17,381,000 | 49.93% | ||
| 2 | FMR LLC | 1,913,520 | 12,361,000 | 35.51% | ||
| 3 | Palo Alto Investors LP | 454,545 | 2,936,000 | 8.43% | ||
| 4 | ACUTA CAPITAL PARTNERS, LLC | 123,249 | 796,000 | 2.29% | ||
| 5 | JPMORGAN CHASE & CO | 77,406 | 500,000 | 1.44% | ||
| 6 | SABBY MANAGEMENT, LLC | 27,505 | 178,000 | 0.51% | ||
| 7 | GOLDMAN SACHS GROUP INC | 20,746 | 134,000 | 0.38% | ||
| 8 | MILLENNIUM MANAGEMENT LLC | 19,254 | 124,000 | 0.36% | ||
| 9 | BlackRock Fund Advisors | 16,348 | 106,000 | 0.30% | ||
| 10 | CARL DOMINO INC | 14,300 | 92,000 | 0.26% | ||
| 11 | J.P. Morgan Private Wealth Advisors LLC | 11,671 | 75,000 | 0.22% | ||
| 12 | BANK OF AMERICA CORP /DE/ | 11,236 | 73,000 | 0.21% | ||
| 13 | CITIGROUP INC | 2,700 | 17,000 | 0.05% | ||
| 14 | MORGAN STANLEY | 1,750 | 11,000 | 0.03% | ||
| 15 | BLACKROCK ADVISORS LLC | 1,354 | 9,000 | 0.03% | ||
| 16 | JBF Capital, Inc. | 1,000 | 6,000 | 0.02% | ||
| 17 | BlackRock Investment Management, LLC | 979 | 6,000 | 0.02% | ||
| 18 | BlackRock Japan Co. Ltd | 599 | 4,000 | 0.01% | ||
| 19 | Tower Research Capital LLC (TRC) | 200 | 1,000 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
