| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | WELLINGTON MANAGEMENT GROUP LLP | 5,374,659 | 31,711,000 | 47.37% | ||
| 2 | ORBIMED ADVISORS LLC | 2,667,500 | 15,738,000 | 23.51% | ||
| 3 | RENAISSANCE TECHNOLOGIES LLC | 1,475,000 | 8,703,000 | 13.00% | ||
| 4 | UNITED SERVICES AUTOMOBILE ASSOCIATION | 346,215 | 2,043,000 | 3.05% | ||
| 5 | Freedom Investment Management, Inc. | 221,611 | 1,308,000 | 1.95% | ||
| 6 | ACUTA CAPITAL PARTNERS, LLC | 204,358 | 1,206,000 | 1.80% | ||
| 7 | Invesco Ltd. | 114,088 | 673,000 | 1.01% | ||
| 8 | CITIGROUP INC | 109,198 | 644,000 | 0.96% | ||
| 9 | Pine River Capital Management L.P. | 106,198 | 627,000 | 0.94% | ||
| 10 | TWO SIGMA INVESTMENTS, LP | 91,301 | 539,000 | 0.81% | ||
| 11 | CREDIT SUISSE AG/ | 89,428 | 527,000 | 0.79% | ||
| 12 | DEUTSCHE BANK AG\ | 83,230 | 491,000 | 0.73% | ||
| 13 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 64,700 | 382,000 | 0.57% | ||
| 14 | GLG Partners LP | 57,800 | 341,000 | 0.51% | ||
| 15 | MORGAN STANLEY | 49,293 | 291,000 | 0.43% | ||
| 16 | PANAGORA ASSET MANAGEMENT INC | 42,337 | 250,000 | 0.37% | ||
| 17 | STATE STREET CORP | 36,718 | 216,000 | 0.32% | ||
| 18 | OMERS ADMINISTRATION Corp | 35,700 | 211,000 | 0.32% | ||
| 19 | TWO SIGMA ADVISERS, LP | 33,700 | 199,000 | 0.30% | ||
| 20 | Verity Asset Management, Inc. | 29,726 | 175,000 | 0.26% | ||
| 21 | GUGGENHEIM CAPITAL LLC | 24,755 | 146,000 | 0.22% | ||
| 22 | GEODE CAPITAL MANAGEMENT, LLC | 23,297 | 137,000 | 0.20% | ||
| 23 | TFS CAPITAL LLC | 15,683 | 93,000 | 0.14% | ||
| 24 | CITADEL ADVISORS LLC | 13,084 | 77,000 | 0.12% | ||
| 25 | GENOVESE BURFORD & BROTHERS WEALTH & RETIREMENT PLAN MANAGEMENT, LLC | 9,950 | 58,000 | 0.09% | ||
| 26 | SIMPLEX TRADING, LLC | 8,154 | 48,000 | 0.07% | ||
| 27 | JPMORGAN CHASE & CO | 4,506 | 27,000 | 0.04% | ||
| 28 | ADVISOR GROUP, INC. | 3,900 | 23,000 | 0.03% | ||
| 29 | CUTLER GROUP LLC / CA | 2,800 | 16,000 | 0.02% | ||
| 30 | Tower Research Capital LLC (TRC) | 2,248 | 14,000 | 0.02% | ||
| 31 | WELLS FARGO & COMPANY/MN | 1,250 | 7,000 | 0.01% | ||
| 32 | UBS Group AG | 1,000 | 6,000 | 0.01% | ||
| 33 | IFP ADVISORS, INC | 1,000 | 6,000 | 0.01% | ||
| 34 | CWM, LLC | 500 | 3,000 | 0.00% | ||
| 35 | Creative Planning | 500 | 3,000 | 0.00% | ||
| 36 | LADENBURG THALMANN FINANCIAL SERVICES INC. | 300 | 2,000 | 0.00% | ||
| 37 | CUTLER GROUP LLC / CA | 200 | 0 | 0.00% | Put |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
