| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 6,290,894 | 91,344,000 | 13.96% | ||
| 2 | Visium Asset Management, LP | 3,592,940 | 52,169,000 | 7.97% | ||
| 3 | WELLS FARGO & COMPANY/MN | 3,191,457 | 46,339,000 | 7.08% | ||
| 4 | OAK RIDGE INVESTMENTS LLC | 3,027,475 | 43,959,000 | 6.72% | ||
| 5 | ArrowMark Colorado Holdings LLC | 2,846,788 | 41,335,000 | 6.32% | ||
| 6 | FRANKLIN RESOURCES INC | 2,557,108 | 37,130,000 | 5.67% | ||
| 7 | BAMCO INC /NY/ | 1,772,488 | 25,737,000 | 3.93% | ||
| 8 | VANGUARD GROUP INC | 1,627,122 | 23,625,000 | 3.61% | ||
| 9 | MILLENNIUM MANAGEMENT LLC | 1,569,180 | 22,784,000 | 3.48% | ||
| 10 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 1,250,000 | 18,150,000 | 2.77% | ||
| 11 | BlackRock Institutional Trust Company, N.A. | 1,146,486 | 16,647,000 | 2.54% | ||
| 12 | TAMARACK ADVISERS, LP | 1,100,000 | 15,972,000 | 2.44% | SH | |
| 13 | BlackRock Fund Advisors | 1,008,601 | 14,645,000 | 2.24% | ||
| 14 | OppenheimerFunds, Inc. | 872,581 | 12,670,000 | 1.94% | ||
| 15 | WELLINGTON MANAGEMENT GROUP LLP | 781,091 | 11,341,000 | 1.73% | ||
| 16 | BRIDGER MANAGEMENT, LLC | 748,642 | 10,870,000 | 1.66% | ||
| 17 | Wellington Shields & Co., LLC | 747,984 | 10,861,000 | 1.66% | ||
| 18 | STATE STREET CORP | 725,683 | 10,536,000 | 1.61% | ||
| 19 | NORTHERN TRUST CORP | 667,943 | 9,699,000 | 1.48% | ||
| 20 | Cortina Asset Management, LLC | 538,154 | 7,814,000 | 1.19% | ||
| 21 | BALYASNY ASSET MANAGEMENT L.P. | 530,000 | 7,696,000 | 1.18% | ||
| 22 | Endurant Capital Management LP | 432,726 | 6,283,000 | 0.96% | ||
| 23 | Granahan Investment Management, LLC | 408,618 | 5,933,000 | 0.91% | ||
| 24 | Artal Group S.A. | 350,000 | 5,082,000 | 0.78% | ||
| 25 | Ghost Tree Capital, LLC | 350,000 | 5,082,000 | 0.78% | ||
| 26 | GEODE CAPITAL MANAGEMENT, LLC | 302,463 | 4,391,000 | 0.67% | ||
| 27 | PFM Health Sciences, LP | 293,580 | 4,263,000 | 0.65% | ||
| 28 | First Light Asset Management, LLC | 283,220 | 4,112,000 | 0.63% | ||
| 29 | PURA VIDA INVESTMENTS, LLC | 270,989 | 3,935,000 | 0.60% | ||
| 30 | PERCEPTIVE ADVISORS LLC | 267,070 | 3,877,000 | 0.59% | ||
| 31 | Bank of New York Mellon Corp | 249,742 | 3,627,000 | 0.55% | ||
| 32 | AMERIPRISE FINANCIAL INC | 249,240 | 3,619,000 | 0.55% | ||
| 33 | Penn Capital Management Company, LLC | 247,355 | 3,592,000 | 0.55% | ||
| 34 | DISCIPLINED GROWTH INVESTORS INC /MN | 241,011 | 3,499,000 | 0.53% | ||
| 35 | CHARTWELL INVESTMENT PARTNERS, LLC | 240,579 | 3,493,000 | 0.53% | ||
| 36 | Novo Holdings A/S | 236,826 | 3,439,000 | 0.53% | ||
| 37 | Pine River Capital Management L.P. | 230,765 | 3,351,000 | 0.51% | ||
| 38 | COLUMBUS CIRCLE INVESTORS | 175,935 | 2,555,000 | 0.39% | ||
| 39 | ARMISTICE CAPITAL, LLC | 172,000 | 2,497,000 | 0.38% | ||
| 40 | C WorldWide Group Holding A/S | 159,956 | 2,323,000 | 0.35% | ||
| 41 | KORNITZER CAPITAL MANAGEMENT INC /KS | 156,560 | 2,273,000 | 0.35% | ||
| 42 | Nicholas Investment Partners, LP | 156,012 | 2,265,000 | 0.35% | ||
| 43 | PNC FINANCIAL SERVICES GROUP, INC. | 154,927 | 2,249,000 | 0.34% | ||
| 44 | BlackRock Investment Management, LLC | 145,847 | 2,118,000 | 0.32% | ||
| 45 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 145,302 | 2,110,000 | 0.32% | ||
| 46 | TIAA CREF INVESTMENT MANAGEMENT LLC | 136,771 | 1,986,000 | 0.30% | ||
| 47 | UNITED SERVICES AUTOMOBILE ASSOCIATION | 127,600 | 1,853,000 | 0.28% | ||
| 48 | Iguana Healthcare Management, LLC | 110,000 | 1,597,000 | 0.24% | ||
| 49 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 102,400 | 1,487,000 | 0.23% | Call | |
| 50 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 89,741 | 1,303,000 | 0.20% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
