| 1 |
FMR LLC |
3,557,779 |
12,452,000 |
31.78% |
|
|
| 2 |
EcoR1 Capital, LLC |
2,292,659 |
8,024,000 |
20.48% |
|
|
| 3 |
Polaris Venture Management Co. V, L.L.C. |
1,827,992 |
6,398,000 |
16.33% |
|
|
| 4 |
Alyeska Investment Group, L.P. |
809,642 |
2,834,000 |
7.23% |
|
|
| 5 |
BlackRock Finance, Inc. |
577,171 |
2,021,000 |
5.16% |
|
|
| 6 |
Rock Springs Capital Management LP |
475,000 |
1,663,000 |
4.24% |
|
|
| 7 |
VANGUARD GROUP INC |
435,324 |
1,524,000 |
3.89% |
|
|
| 8 |
GLEN HARBOR CAPITAL MANAGEMENT LLC |
153,238 |
536,000 |
1.37% |
|
|
| 9 |
MEADOW CREEK INVESTMENT MANAGEMENT LLC |
126,196 |
442,000 |
1.13% |
|
|
| 10 |
GEODE CAPITAL MANAGEMENT, LLC |
112,178 |
392,000 |
1.00% |
|
|
| 11 |
BRIDGEWAY CAPITAL MANAGEMENT, LLC |
102,697 |
359,000 |
0.92% |
|
|
| 12 |
ELKFORK PARTNERS LLC |
99,154 |
347,000 |
0.89% |
|
|
| 13 |
RIVERHEAD CAPITAL MANAGEMENT LLC |
79,677 |
279,000 |
0.71% |
|
|
| 14 |
TYERS ASSET MANAGEMENT LLC |
72,112 |
252,000 |
0.64% |
|
|
| 15 |
DIMENSIONAL FUND ADVISORS LP |
58,172 |
204,000 |
0.52% |
|
|
| 16 |
BANK OF AMERICA CORP /DE/ |
47,708 |
167,000 |
0.43% |
|
|
| 17 |
Connor, Clark & Lunn Investment Management Ltd. |
43,100 |
151,000 |
0.39% |
|
|
| 18 |
RENAISSANCE TECHNOLOGIES LLC |
38,800 |
136,000 |
0.35% |
|
|
| 19 |
NORTHERN TRUST CORP |
35,220 |
123,000 |
0.31% |
|
|
| 20 |
GOLDMAN SACHS GROUP INC |
32,074 |
112,000 |
0.29% |
|
|
| 21 |
MILLENNIUM MANAGEMENT LLC |
29,427 |
103,000 |
0.26% |
|
|
| 22 |
Bank of New York Mellon Corp |
27,454 |
96,000 |
0.25% |
|
|
| 23 |
MORGAN STANLEY |
25,308 |
89,000 |
0.23% |
|
|
| 24 |
ALAMBIC INVESTMENT MANAGEMENT, L.P. |
22,200 |
78,000 |
0.20% |
|
|
| 25 |
Quotient Investors, LLC |
22,200 |
78,000 |
0.20% |
|
|
| 26 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
19,339 |
68,000 |
0.17% |
|
|
| 27 |
Dynamic Technology Lab Private Ltd |
19,344 |
68,000 |
0.17% |
|
|
| 28 |
Creative Planning |
18,200 |
64,000 |
0.16% |
|
|
| 29 |
Perkins Investment Management, LLC |
16,000 |
56,000 |
0.14% |
|
|
| 30 |
CITIGROUP INC |
7,800 |
27,000 |
0.07% |
|
|
| 31 |
ACADIAN ASSET MANAGEMENT LLC |
5,122 |
18,000 |
0.05% |
|
|
| 32 |
D.A. DAVIDSON & CO. |
2,000 |
7,000 |
0.02% |
|
|
| 33 |
Parallax Volatility Advisers, L.P. |
1,300 |
5,000 |
0.01% |
|
|
| 34 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
799 |
3,000 |
0.01% |
|
|
| 35 |
IFP ADVISORS, INC |
500 |
2,000 |
0.01% |
|
|
| 36 |
FEDERATED HERMES, INC. |
327 |
1,000 |
0.00% |
|
|
| 37 |
ROYAL BANK OF CANADA |
7 |
0 |
0.00% |
|
|
| 38 |
UBS Group AG |
95 |
0 |
0.00% |
|
|
| 39 |
BARCLAYS PLC |
68 |
0 |
0.00% |
|
|
