| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FEDERATED HERMES, INC. | 4,041,793 | 12,853,000 | 13.85% | ||
| 2 | BlackRock Institutional Trust Company, N.A. | 2,160,646 | 6,871,000 | 7.40% | ||
| 3 | BAKER BROS. ADVISORS LP | 2,155,516 | 6,855,000 | 7.38% | ||
| 4 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 1,946,594 | 6,190,000 | 6.67% | ||
| 5 | FRANKLIN RESOURCES INC | 1,888,300 | 6,005,000 | 6.47% | ||
| 6 | VANGUARD GROUP INC | 1,531,443 | 4,870,000 | 5.25% | ||
| 7 | BlackRock Fund Advisors | 1,474,656 | 4,689,000 | 5.05% | ||
| 8 | First Eagle Investment Management, LLC | 1,377,448 | 4,380,000 | 4.72% | ||
| 9 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 1,316,461 | 4,186,000 | 4.51% | ||
| 10 | FMR LLC | 1,063,654 | 3,382,000 | 3.64% | ||
| 11 | AXA S.A. | 1,002,017 | 3,186,000 | 3.43% | ||
| 12 | STATE STREET CORP | 963,237 | 3,061,000 | 3.30% | ||
| 13 | MILLENNIUM MANAGEMENT LLC | 726,334 | 2,310,000 | 2.49% | ||
| 14 | JPMORGAN CHASE & CO | 670,300 | 2,131,000 | 2.30% | ||
| 15 | NORTHERN TRUST CORP | 565,075 | 1,797,000 | 1.94% | ||
| 16 | DAFNA Capital Management LLC | 530,965 | 1,688,000 | 1.82% | ||
| 17 | CREDIT SUISSE AG/ | 444,474 | 1,414,000 | 1.52% | ||
| 18 | DEUTSCHE BANK AG\ | 441,807 | 1,403,000 | 1.51% | ||
| 19 | GOLDMAN SACHS GROUP INC | 351,100 | 1,116,000 | 1.20% | Call | |
| 20 | MORGAN STANLEY | 347,208 | 1,104,000 | 1.19% | ||
| 21 | Bank of New York Mellon Corp | 267,851 | 852,000 | 0.92% | ||
| 22 | GEODE CAPITAL MANAGEMENT, LLC | 256,003 | 814,000 | 0.88% | ||
| 23 | ROYAL BANK OF CANADA | 254,905 | 811,000 | 0.87% | ||
| 24 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 199,100 | 763,000 | 0.82% | ||
| 25 | PUTNAM INVESTMENTS LLC | 215,774 | 686,000 | 0.74% | ||
| 26 | TIAA CREF INVESTMENT MANAGEMENT LLC | 214,422 | 682,000 | 0.73% | ||
| 27 | Rhenman & Partners Asset Management AB | 201,537 | 641,000 | 0.69% | ||
| 28 | RENAISSANCE TECHNOLOGIES LLC | 177,615 | 565,000 | 0.61% | ||
| 29 | PERCEPTIVE ADVISORS LLC | 160,000 | 509,000 | 0.55% | ||
| 30 | BlackRock Investment Management, LLC | 154,792 | 492,000 | 0.53% | ||
| 31 | TFS CAPITAL LLC | 145,213 | 462,000 | 0.50% | ||
| 32 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 132,816 | 422,000 | 0.45% | ||
| 33 | TOCQUEVILLE ASSET MANAGEMENT L.P. | 125,000 | 398,000 | 0.43% | ||
| 34 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 96,415 | 307,000 | 0.33% | ||
| 35 | BLACKROCK ADVISORS LLC | 93,636 | 298,000 | 0.32% | ||
| 36 | FORTALEZA ASSET MANAGEMENT INC/ | 89,930 | 286,000 | 0.31% | ||
| 37 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 88,794 | 283,000 | 0.30% | ||
| 38 | HighTower Advisors, LLC | 78,477 | 250,000 | 0.27% | ||
| 39 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 78,500 | 250,000 | 0.27% | Put | |
| 40 | CITADEL ADVISORS LLC | 75,592 | 241,000 | 0.26% | ||
| 41 | WELLS FARGO & COMPANY/MN | 72,435 | 231,000 | 0.25% | ||
| 42 | TEACHERS ADVISORS, LLC | 63,426 | 202,000 | 0.22% | ||
| 43 | STIFEL FINANCIAL CORP | 59,350 | 189,000 | 0.20% | ||
| 44 | ALLIANCEBERNSTEIN L.P. | 53,800 | 171,000 | 0.18% | ||
| 45 | CORNERSTONE CAPITAL MANAGEMENT HOLDINGS LLC. | 50,300 | 160,000 | 0.17% | ||
| 46 | GAM Holding AG | 50,000 | 159,000 | 0.17% | ||
| 47 | FRANKLIN STREET ADVISORS INC /NC | 50,000 | 159,000 | 0.17% | ||
| 48 | RHUMBLINE ADVISERS | 44,221 | 141,000 | 0.15% | ||
| 49 | AMERICAN INTERNATIONAL GROUP, INC. | 43,646 | 138,794 | 0.15% | ||
| 50 | VOYA INVESTMENT MANAGEMENT LLC | 42,200 | 134,000 | 0.14% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
