| 1 |
ADAGE CAPITAL PARTNERS GP, L.L.C. |
3,500,000 |
2,224,000 |
17.34% |
|
|
| 2 |
First Eagle Investment Management, LLC |
3,199,433 |
2,033,000 |
15.85% |
|
|
| 3 |
VANGUARD GROUP INC |
2,697,460 |
1,714,000 |
13.37% |
|
|
| 4 |
DEERFIELD MANAGEMENT COMPANY, L.P. |
2,583,160 |
1,641,000 |
12.80% |
|
|
| 5 |
Sio Capital Management, LLC |
1,333,490 |
847,000 |
6.61% |
|
|
| 6 |
BlackRock Institutional Trust Company, N.A. |
1,255,911 |
798,000 |
6.22% |
|
|
| 7 |
Cormorant Asset Management, LP |
1,012,255 |
643,000 |
5.01% |
|
|
| 8 |
RENAISSANCE TECHNOLOGIES LLC |
774,763 |
492,000 |
3.84% |
|
|
| 9 |
MILLENNIUM MANAGEMENT LLC |
444,955 |
283,000 |
2.21% |
|
|
| 10 |
FMR LLC |
393,754 |
250,000 |
1.95% |
|
|
| 11 |
GEODE CAPITAL MANAGEMENT, LLC |
351,290 |
223,000 |
1.74% |
|
|
| 12 |
Paloma Partners Management Co |
238,481 |
152,000 |
1.19% |
|
|
| 13 |
OXFORD ASSET MANAGEMENT LLP |
202,522 |
129,000 |
1.01% |
|
|
| 14 |
Rhenman & Partners Asset Management AB |
201,537 |
128,000 |
1.00% |
|
|
| 15 |
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM |
199,100 |
127,000 |
0.99% |
|
|
| 16 |
CREDIT SUISSE AG/ |
197,207 |
125,000 |
0.97% |
|
|
| 17 |
GOLDMAN SACHS GROUP INC |
167,745 |
107,000 |
0.83% |
|
|
| 18 |
CITADEL ADVISORS LLC |
134,431 |
85,000 |
0.66% |
|
|
| 19 |
NORTHERN TRUST CORP |
105,707 |
67,000 |
0.52% |
|
|
| 20 |
Bank of New York Mellon Corp |
87,965 |
56,000 |
0.44% |
|
|
| 21 |
Alpine Global Management, LLC |
85,791 |
55,000 |
0.43% |
|
|
| 22 |
LMR Partners LLP |
80,123 |
51,000 |
0.40% |
|
|
| 23 |
HighTower Advisors, LLC |
79,227 |
50,000 |
0.39% |
|
|
| 24 |
TWO SIGMA ADVISERS, LP |
76,100 |
48,000 |
0.37% |
|
|
| 25 |
FRANKLIN STREET ADVISORS INC /NC |
70,000 |
44,000 |
0.34% |
|
|
| 26 |
BLACKROCK ADVISORS LLC |
65,499 |
42,000 |
0.33% |
|
|
| 27 |
Squarepoint Ops LLC |
65,200 |
41,000 |
0.32% |
|
|
| 28 |
INTEGRAL DERIVATIVES, LLC |
56,597 |
36,000 |
0.28% |
|
|
| 29 |
STATE STREET CORP |
54,529 |
34,000 |
0.27% |
|
|
| 30 |
D. E. Shaw & Co., Inc. |
52,675 |
33,000 |
0.26% |
|
|
| 31 |
PANAGORA ASSET MANAGEMENT INC |
41,984 |
27,000 |
0.21% |
|
|
| 32 |
TWO SIGMA INVESTMENTS, LP |
39,350 |
25,000 |
0.19% |
|
|
| 33 |
DEUTSCHE BANK AG\ |
37,195 |
23,000 |
0.18% |
|
|
| 34 |
ACADIAN ASSET MANAGEMENT LLC |
31,237 |
20,000 |
0.16% |
|
|
| 35 |
SIMPLEX TRADING, LLC |
29,570 |
18,000 |
0.14% |
|
|
| 36 |
WEDBUSH SECURITIES INC |
24,000 |
15,000 |
0.12% |
|
|
| 37 |
BLAIR WILLIAM & CO/IL |
24,120 |
15,000 |
0.12% |
|
|
| 38 |
GUGGENHEIM CAPITAL LLC |
22,900 |
15,000 |
0.12% |
|
|
| 39 |
GROUP ONE TRADING LLC |
22,247 |
14,000 |
0.11% |
|
|
| 40 |
MORGAN STANLEY |
21,869 |
13,000 |
0.10% |
|
|
| 41 |
BANK OF AMERICA CORP /DE/ |
18,697 |
12,000 |
0.09% |
|
|
| 42 |
CUTLER GROUP LLC / CA |
17,991 |
11,000 |
0.09% |
|
|
| 43 |
Compagnie Lombard Odier SCmA |
13,504 |
9,000 |
0.07% |
|
|
| 44 |
UBS Group AG |
12,585 |
8,000 |
0.06% |
|
|
| 45 |
BlackRock Fund Advisors |
11,711 |
7,000 |
0.05% |
|
|
| 46 |
First Allied Advisory Services, Inc. |
11,500 |
7,000 |
0.05% |
|
|
| 47 |
LADENBURG THALMANN FINANCIAL SERVICES INC. |
8,600 |
6,000 |
0.05% |
|
|
| 48 |
WOLVERINE TRADING LP /BD |
72 |
4,197 |
0.03% |
Call |
|
| 49 |
WOLVERINE TRADING LP /BD |
5,697 |
3,321 |
0.03% |
|
|
| 50 |
BlackRock Japan Co. Ltd |
4,033 |
3,000 |
0.02% |
|
|
