| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 1,671,041 | 18,031,000 | 11.44% | ||
| 2 | Deer VII & Co. Ltd. | 1,190,358 | 12,844,000 | 8.15% | ||
| 3 | JPMORGAN CHASE & CO | 1,075,347 | 11,603,000 | 7.36% | ||
| 4 | Tekla Capital Management LLC | 918,827 | 9,914,000 | 6.29% | ||
| 5 | MPM ASSET MANAGEMENT LLC | 816,683 | 8,812,000 | 5.59% | ||
| 6 | BlackRock Fund Advisors | 794,894 | 8,577,000 | 5.44% | ||
| 7 | PLATINUM INVESTMENT MANAGEMENT LTD | 781,003 | 8,427,000 | 5.34% | ||
| 8 | First Eagle Investment Management, LLC | 511,254 | 5,516,000 | 3.50% | ||
| 9 | JENNISON ASSOCIATES LLC | 503,644 | 5,434,000 | 3.45% | ||
| 10 | EMERALD ADVISERS, LLC | 486,601 | 5,250,000 | 3.33% | ||
| 11 | VANGUARD GROUP INC | 413,142 | 4,458,000 | 2.83% | ||
| 12 | PUTNAM INVESTMENTS LLC | 394,861 | 4,261,000 | 2.70% | ||
| 13 | BLACKROCK ADVISORS LLC | 393,103 | 4,242,000 | 2.69% | ||
| 14 | EMERALD MUTUAL FUND ADVISERS TRUST | 340,819 | 3,677,000 | 2.33% | ||
| 15 | WALL STREET ASSOCIATES | 330,100 | 3,562,000 | 2.26% | ||
| 16 | LORD, ABBETT & CO. LLC | 325,629 | 3,514,000 | 2.23% | ||
| 17 | UBS AG | 299,960 | 3,237,000 | 2.05% | ||
| 18 | STATE STREET CORP | 253,983 | 2,739,000 | 1.74% | ||
| 19 | HOWLAND CAPITAL MANAGEMENT LLC | 227,165 | 2,451,000 | 1.55% | ||
| 20 | PERCEPTIVE ADVISORS LLC | 220,000 | 2,391,000 | 1.52% | ||
| 21 | QVT Financial LP | 216,801 | 2,339,000 | 1.48% | ||
| 22 | NORTHERN TRUST CORP | 214,737 | 2,317,000 | 1.47% | ||
| 23 | FRANKLIN RESOURCES INC | 204,300 | 2,204,000 | 1.40% | ||
| 24 | BRIDGER MANAGEMENT, LLC | 200,000 | 2,158,000 | 1.37% | ||
| 25 | MARXE AUSTIN W & GREENHOUSE DAVID M | 180,000 | 1,942,000 | 1.23% | ||
| 26 | BlackRock Institutional Trust Company, N.A. | 176,967 | 1,909,000 | 1.21% | ||
| 27 | MCKINLEY CAPITAL MANAGEMENT LLC | 171,248 | 1,848,000 | 1.17% | ||
| 28 | OXFORD ASSET MANAGEMENT LLP | 140,623 | 1,517,000 | 0.96% | ||
| 29 | SMITH ASSET MANAGEMENT GROUP LP | 123,550 | 1,333,000 | 0.85% | ||
| 30 | BlackRock Group LTD | 98,840 | 1,066,000 | 0.68% | ||
| 31 | Bank of New York Mellon Corp | 79,235 | 855,000 | 0.54% | ||
| 32 | GEODE CAPITAL MANAGEMENT, LLC | 79,069 | 853,000 | 0.54% | ||
| 33 | CREDIT SUISSE AG/ | 69,747 | 752,000 | 0.48% | ||
| 34 | TIAA CREF INVESTMENT MANAGEMENT LLC | 63,021 | 680,000 | 0.43% | ||
| 35 | HAMILTON LANE ADVISORS LLC | 62,720 | 677,000 | 0.43% | ||
| 36 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 50,000 | 540,000 | 0.34% | ||
| 37 | BlackRock Investment Management, LLC | 48,322 | 521,000 | 0.33% | ||
| 38 | STONERIDGE INVESTMENT PARTNERS LLC | 41,920 | 452,000 | 0.29% | ||
| 39 | ProShare Advisors LLC | 37,163 | 401,000 | 0.25% | ||
| 40 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 31,372 | 339,000 | 0.22% | ||
| 41 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 30,000 | 324,000 | 0.21% | ||
| 42 | MIDDLETON & CO INC/MA | 27,350 | 295,000 | 0.19% | ||
| 43 | TEACHERS ADVISORS, LLC | 26,722 | 288,000 | 0.18% | ||
| 44 | MILLENNIUM MANAGEMENT LLC | 24,090 | 260,000 | 0.16% | ||
| 45 | MORGAN STANLEY | 22,657 | 244,000 | 0.15% | ||
| 46 | BlackRock Finance, Inc. | 20,215 | 218,000 | 0.14% | ||
| 47 | MOODY NATIONAL BANK TRUST DIVISION | 20,000 | 216,000 | 0.14% | ||
| 48 | ALLIANCEBERNSTEIN L.P. | 19,913 | 215,000 | 0.14% | ||
| 49 | Moab Capital Partners LLC | 16,500 | 178,000 | 0.11% | ||
| 50 | STEVENS CAPITAL MANAGEMENT LP | 16,411 | 177,000 | 0.11% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
