| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | PLATINUM INVESTMENT MANAGEMENT LTD | 1,700,830 | 14,491,000 | 11.59% | ||
| 2 | FMR LLC | 1,546,041 | 13,172,000 | 10.53% | ||
| 3 | Deer VII & Co. Ltd. | 1,190,358 | 10,142,000 | 8.11% | ||
| 4 | Tekla Capital Management LLC | 1,149,827 | 9,797,000 | 7.83% | ||
| 5 | JPMORGAN CHASE & CO | 1,071,635 | 9,130,000 | 7.30% | ||
| 6 | MPM ASSET MANAGEMENT LLC | 816,683 | 6,958,000 | 5.56% | ||
| 7 | BlackRock Fund Advisors | 805,111 | 6,860,000 | 5.48% | ||
| 8 | UBS AG | 656,426 | 5,593,000 | 4.47% | ||
| 9 | VANGUARD GROUP INC | 549,108 | 4,679,000 | 3.74% | ||
| 10 | First Eagle Investment Management, LLC | 512,254 | 4,364,000 | 3.49% | ||
| 11 | JENNISON ASSOCIATES LLC | 448,765 | 3,823,000 | 3.06% | ||
| 12 | PUTNAM INVESTMENTS LLC | 393,261 | 3,351,000 | 2.68% | ||
| 13 | STATE STREET CORP | 299,180 | 2,551,000 | 2.04% | ||
| 14 | WALL STREET ASSOCIATES | 296,200 | 2,524,000 | 2.02% | ||
| 15 | LORD, ABBETT & CO. LLC | 292,354 | 2,491,000 | 1.99% | ||
| 16 | MCKINLEY CAPITAL MANAGEMENT LLC | 289,104 | 2,463,000 | 1.97% | ||
| 17 | HOWLAND CAPITAL MANAGEMENT LLC | 288,671 | 2,459,000 | 1.97% | ||
| 18 | COMMONWEALTH BANK OF AUSTRALIA | 287,198 | 2,447,000 | 1.96% | ||
| 19 | BlackRock Institutional Trust Company, N.A. | 212,819 | 1,813,000 | 1.45% | ||
| 20 | NORTHERN TRUST CORP | 212,271 | 1,808,000 | 1.45% | ||
| 21 | MARXE AUSTIN W & GREENHOUSE DAVID M | 140,000 | 1,193,000 | 0.95% | ||
| 22 | TWIN FOCUS CAPITAL PARTNERS, LLC | 139,207 | 1,186,000 | 0.95% | ||
| 23 | GEODE CAPITAL MANAGEMENT, LLC | 118,980 | 1,013,000 | 0.81% | ||
| 24 | SMITH ASSET MANAGEMENT GROUP LP | 117,390 | 1,000,000 | 0.80% | ||
| 25 | Bank of New York Mellon Corp | 85,123 | 726,000 | 0.58% | ||
| 26 | TIAA CREF INVESTMENT MANAGEMENT LLC | 82,828 | 706,000 | 0.56% | ||
| 27 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 75,000 | 639,000 | 0.51% | ||
| 28 | BlackRock Investment Management, LLC | 68,695 | 585,000 | 0.47% | ||
| 29 | RENAISSANCE TECHNOLOGIES LLC | 66,300 | 565,000 | 0.45% | ||
| 30 | BLACKROCK ADVISORS LLC | 53,704 | 458,000 | 0.37% | ||
| 31 | HIGHBRIDGE CAPITAL MANAGEMENT LLC | 46,860 | 399,000 | 0.32% | ||
| 32 | OXFORD ASSET MANAGEMENT LLP | 45,381 | 391,000 | 0.31% | ||
| 33 | HAMILTON LANE ADVISORS LLC | 42,720 | 364,000 | 0.29% | ||
| 34 | STONERIDGE INVESTMENT PARTNERS LLC | 40,760 | 347,000 | 0.28% | ||
| 35 | MOODY NATIONAL BANK TRUST DIVISION | 40,000 | 341,000 | 0.27% | ||
| 36 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 38,491 | 328,000 | 0.26% | ||
| 37 | MIDDLETON & CO INC/MA | 37,130 | 316,000 | 0.25% | ||
| 38 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 30,000 | 256,000 | 0.20% | ||
| 39 | MORGAN STANLEY | 24,949 | 212,000 | 0.17% | ||
| 40 | RHUMBLINE ADVISERS | 23,707 | 202,000 | 0.16% | ||
| 41 | EMERALD ADVISERS, LLC | 23,575 | 201,000 | 0.16% | ||
| 42 | TEACHERS ADVISORS, LLC | 23,543 | 201,000 | 0.16% | ||
| 43 | ProShare Advisors LLC | 21,549 | 184,000 | 0.15% | ||
| 44 | EVENTIDE ASSET MANAGEMENT, LLC | 20,900 | 178,000 | 0.14% | ||
| 45 | CREDIT SUISSE AG/ | 19,461 | 166,000 | 0.13% | ||
| 46 | ALLIANCEBERNSTEIN L.P. | 18,190 | 155,000 | 0.12% | ||
| 47 | JANE STREET GROUP, LLC | 16,898 | 144,000 | 0.12% | ||
| 48 | Capital Impact Advisors, LLC | 16,605 | 141,000 | 0.11% | ||
| 49 | Moab Capital Partners LLC | 16,500 | 141,000 | 0.11% | ||
| 50 | Nationwide Fund Advisors | 16,091 | 137,000 | 0.11% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
