| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 2,296,041 | 23,351,000 | 11.62% | ||
| 2 | PLATINUM INVESTMENT MANAGEMENT LTD | 1,730,913 | 17,603,000 | 8.76% | ||
| 3 | Tekla Capital Management LLC | 1,249,827 | 12,711,000 | 6.33% | ||
| 4 | Deer VII & Co. Ltd. | 1,190,358 | 12,106,000 | 6.03% | ||
| 5 | BlackRock Fund Advisors | 1,188,494 | 12,087,000 | 6.02% | ||
| 6 | Broadfin Capital, LLC | 1,050,000 | 10,679,000 | 5.32% | ||
| 7 | UBS Group AG | 844,005 | 8,583,000 | 4.27% | ||
| 8 | VANGUARD GROUP INC | 840,458 | 8,548,000 | 4.26% | ||
| 9 | MPM ASSET MANAGEMENT LLC | 816,683 | 8,306,000 | 4.13% | ||
| 10 | AXA S.A. | 613,776 | 6,242,000 | 3.11% | ||
| 11 | LORD, ABBETT & CO. LLC | 468,589 | 4,765,000 | 2.37% | ||
| 12 | BlackRock Institutional Trust Company, N.A. | 461,432 | 4,693,000 | 2.34% | ||
| 13 | JENNISON ASSOCIATES LLC | 449,584 | 4,572,000 | 2.28% | ||
| 14 | OXFORD ASSET MANAGEMENT LLP | 435,191 | 4,426,000 | 2.20% | ||
| 15 | First Eagle Investment Management, LLC | 427,622 | 4,349,000 | 2.17% | ||
| 16 | AWM Investment Company, Inc. | 400,000 | 4,068,000 | 2.03% | ||
| 17 | PUTNAM INVESTMENTS LLC | 393,261 | 3,999,000 | 1.99% | ||
| 18 | STATE STREET CORP | 376,167 | 3,821,000 | 1.90% | ||
| 19 | HOWLAND CAPITAL MANAGEMENT LLC | 318,654 | 3,241,000 | 1.61% | ||
| 20 | MCKINLEY CAPITAL MANAGEMENT LLC | 287,395 | 2,923,000 | 1.46% | ||
| 21 | WALL STREET ASSOCIATES | 280,700 | 2,855,000 | 1.42% | ||
| 22 | NORTHERN TRUST CORP | 278,382 | 2,831,000 | 1.41% | ||
| 23 | STIFEL FINANCIAL CORP | 236,230 | 2,402,000 | 1.20% | ||
| 24 | First Light Asset Management, LLC | 207,922 | 2,115,000 | 1.05% | ||
| 25 | WELLS FARGO & COMPANY/MN | 200,512 | 2,039,000 | 1.02% | ||
| 26 | Candriam S.C.A. | 200,000 | 2,034,000 | 1.01% | ||
| 27 | BLACKROCK ADVISORS LLC | 195,111 | 1,984,000 | 0.99% | ||
| 28 | GEODE CAPITAL MANAGEMENT, LLC | 179,259 | 1,823,000 | 0.91% | ||
| 29 | Bank of New York Mellon Corp | 153,928 | 1,566,000 | 0.78% | ||
| 30 | JPMORGAN CHASE & CO | 141,135 | 1,435,000 | 0.71% | ||
| 31 | Employees Retirement System of Texas | 129,000 | 1,312,000 | 0.65% | ||
| 32 | RENAISSANCE TECHNOLOGIES LLC | 107,100 | 1,089,000 | 0.54% | ||
| 33 | Catalyst Capital Advisors LLC | 105,000 | 1,068,000 | 0.53% | ||
| 34 | CQS Cayman LP | 100,000 | 1,017,000 | 0.51% | ||
| 35 | TIAA CREF INVESTMENT MANAGEMENT LLC | 98,020 | 997,000 | 0.50% | ||
| 36 | BlackRock Investment Management, LLC | 91,148 | 927,000 | 0.46% | ||
| 37 | STONERIDGE INVESTMENT PARTNERS LLC | 85,875 | 873,000 | 0.43% | ||
| 38 | P.A.W. CAPITAL CORP | 80,000 | 814,000 | 0.41% | ||
| 39 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 75,000 | 763,000 | 0.38% | ||
| 40 | HIGHBRIDGE CAPITAL MANAGEMENT LLC | 64,895 | 660,000 | 0.33% | ||
| 41 | J.P. Morgan Private Wealth Advisors LLC | 59,000 | 600,000 | 0.30% | ||
| 42 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 51,856 | 527,000 | 0.26% | ||
| 43 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 47,100 | 480,000 | 0.24% | ||
| 44 | CITADEL ADVISORS LLC | 46,141 | 469,000 | 0.23% | ||
| 45 | Nine Chapters Capital Management LLC | 43,500 | 442,000 | 0.22% | ||
| 46 | NEW YORK STATE COMMON RETIREMENT FUND | 37,000 | 376,000 | 0.19% | ||
| 47 | TEACHERS ADVISORS, LLC | 35,886 | 365,000 | 0.18% | ||
| 48 | DIMENSIONAL FUND ADVISORS LP | 35,555 | 362,000 | 0.18% | ||
| 49 | RHUMBLINE ADVISERS | 33,482 | 341,000 | 0.17% | ||
| 50 | ProShare Advisors LLC | 32,153 | 327,000 | 0.16% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
