| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FEDERATED HERMES, INC. | 25,064,700 | 50,380,000 | 28.17% | ||
| 2 | FMR LLC | 11,089,697 | 22,290,000 | 12.46% | ||
| 3 | GILDER GAGNON HOWE & CO LLC | 9,094,107 | 18,279,000 | 10.22% | ||
| 4 | Visium Asset Management, LP | 5,413,000 | 10,880,000 | 6.08% | ||
| 5 | Broadfin Capital, LLC | 5,137,645 | 10,327,000 | 5.77% | ||
| 6 | BlackRock Fund Advisors | 4,652,316 | 9,351,000 | 5.23% | ||
| 7 | VANGUARD GROUP INC | 3,444,706 | 6,924,000 | 3.87% | ||
| 8 | MILLENNIUM MANAGEMENT LLC | 2,818,373 | 5,665,000 | 3.17% | ||
| 9 | BAKER BROS. ADVISORS LP | 2,350,400 | 4,724,000 | 2.64% | ||
| 10 | Abingworth LLP | 2,335,218 | 4,670,000 | 2.61% | ||
| 11 | TIVERTON ASSET MANAGEMENT LLC | 2,200,000 | 4,422,000 | 2.47% | ||
| 12 | D. E. Shaw & Co., Inc. | 2,194,584 | 4,411,000 | 2.47% | ||
| 13 | BlackRock Institutional Trust Company, N.A. | 1,380,333 | 2,774,000 | 1.55% | ||
| 14 | STATE STREET CORP | 1,377,350 | 2,768,000 | 1.55% | ||
| 15 | NORTHERN TRUST CORP | 1,181,376 | 2,375,000 | 1.33% | ||
| 16 | WELLINGTON MANAGEMENT GROUP LLP | 820,000 | 1,648,000 | 0.92% | ||
| 17 | ROYCE & ASSOCIATES LP | 734,478 | 1,476,000 | 0.83% | ||
| 18 | GEODE CAPITAL MANAGEMENT, LLC | 600,544 | 1,206,000 | 0.67% | ||
| 19 | Bank of New York Mellon Corp | 538,313 | 1,082,000 | 0.60% | ||
| 20 | OXFORD ASSET MANAGEMENT LLP | 525,640 | 1,045,000 | 0.58% | ||
| 21 | TIAA CREF INVESTMENT MANAGEMENT LLC | 441,695 | 888,000 | 0.50% | ||
| 22 | BLAIR WILLIAM & CO/IL | 426,300 | 856,000 | 0.48% | ||
| 23 | BlackRock Investment Management, LLC | 354,597 | 713,000 | 0.40% | ||
| 24 | BANK OF AMERICA CORP /DE/ | 325,452 | 654,000 | 0.37% | ||
| 25 | FIRST NEW YORK SECURITIES LLC /NY | 200,000 | 569,000 | 0.32% | ||
| 26 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 266,600 | 536,000 | 0.30% | Call | |
| 27 | Healthcare Value Capital, LLC | 250,000 | 503,000 | 0.28% | ||
| 28 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 224,318 | 451,000 | 0.25% | ||
| 29 | TWO SIGMA INVESTMENTS, LP | 208,559 | 419,000 | 0.23% | ||
| 30 | ORBIMED ADVISORS LLC | 207,600 | 417,000 | 0.23% | Call | |
| 31 | TEACHERS ADVISORS, LLC | 172,645 | 347,000 | 0.19% | ||
| 32 | GOLDMAN SACHS GROUP INC | 165,748 | 334,000 | 0.19% | ||
| 33 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 154,900 | 311,000 | 0.17% | ||
| 34 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 154,200 | 310,000 | 0.17% | ||
| 35 | AQR CAPITAL MANAGEMENT LLC | 150,700 | 303,000 | 0.17% | ||
| 36 | ProShare Advisors LLC | 144,582 | 291,000 | 0.16% | ||
| 37 | MORGAN STANLEY | 143,467 | 288,000 | 0.16% | ||
| 38 | DEUTSCHE BANK AG\ | 127,156 | 254,000 | 0.14% | ||
| 39 | CREDIT SUISSE AG/ | 114,859 | 230,000 | 0.13% | ||
| 40 | ALLIANCEBERNSTEIN L.P. | 112,500 | 226,000 | 0.13% | ||
| 41 | VOYA INVESTMENT MANAGEMENT LLC | 99,691 | 200,000 | 0.11% | ||
| 42 | Nationwide Fund Advisors | 93,965 | 189,000 | 0.11% | ||
| 43 | RHUMBLINE ADVISERS | 90,687 | 182,000 | 0.10% | ||
| 44 | LPL Financial LLC | 86,994 | 175,000 | 0.10% | ||
| 45 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 83,855 | 169,000 | 0.09% | ||
| 46 | AMERICAN INTERNATIONAL GROUP, INC. | 80,359 | 161,522 | 0.09% | ||
| 47 | DekaBank Deutsche Girozentrale | 80,100 | 161,000 | 0.09% | ||
| 48 | LADENBURG THALMANN FINANCIAL SERVICES INC. | 68,000 | 137,000 | 0.08% | ||
| 49 | DENVER INVESTMENT ADVISORS LLC | 66,917 | 135,000 | 0.08% | ||
| 50 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 65,900 | 132,000 | 0.07% | Put |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
