| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | RA CAPITAL MANAGEMENT, L.P. | 7,088,651 | 113,064,000 | 51.69% | ||
| 2 | FMR LLC | 2,057,632 | 32,819,000 | 15.00% | ||
| 3 | FORESITE CAPITAL MANAGEMENT III, LLC | 1,410,689 | 22,500,000 | 10.29% | ||
| 4 | Redmile Group, LLC | 1,213,627 | 18,326,000 | 8.38% | ||
| 5 | New Leaf Venture Partners, L.L.C. | 784,159 | 12,507,000 | 5.72% | ||
| 6 | Cormorant Asset Management, LP | 392,079 | 6,254,000 | 2.86% | ||
| 7 | CLOUGH CAPITAL PARTNERS L P | 392,950 | 6,210,000 | 2.84% | ||
| 8 | JENNISON ASSOCIATES LLC | 369,249 | 5,773,000 | 2.64% | ||
| 9 | GEODE CAPITAL MANAGEMENT, LLC | 38,650 | 616,000 | 0.28% | ||
| 10 | GOLDMAN SACHS GROUP INC | 13,943 | 222,000 | 0.10% | ||
| 11 | NORTHERN TRUST CORP | 12,662 | 202,000 | 0.09% | ||
| 12 | NORGES BANK | 4,999 | 80,000 | 0.04% | ||
| 13 | WELLS FARGO & COMPANY/MN | 4,672 | 75,000 | 0.03% | ||
| 14 | UBS Group AG | 3,000 | 48,000 | 0.02% | ||
| 15 | MORGAN STANLEY | 1,057 | 17,000 | 0.01% | ||
| 16 | BLACKROCK ADVISORS LLC | 438 | 7,000 | 0.00% | ||
| 17 | ROYAL BANK OF CANADA | 300 | 5,000 | 0.00% | ||
| 18 | Tower Research Capital LLC (TRC) | 80 | 1,000 | 0.00% | ||
| 19 | CITIGROUP INC | 45 | 1,000 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
