| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | RA CAPITAL MANAGEMENT, L.P. | 7,088,651 | 98,390,000 | 51.17% | ||
| 2 | FMR LLC | 1,972,138 | 27,373,000 | 14.24% | ||
| 3 | FORESITE CAPITAL MANAGEMENT III, LLC | 1,411,749 | 17,855,000 | 9.29% | ||
| 4 | Redmile Group, LLC | 1,238,273 | 16,963,000 | 8.82% | ||
| 5 | New Leaf Venture Partners, L.L.C. | 784,159 | 10,884,000 | 5.66% | ||
| 6 | Cormorant Asset Management, LP | 392,079 | 5,442,000 | 2.83% | ||
| 7 | CLOUGH CAPITAL PARTNERS L P | 373,150 | 5,129,000 | 2.67% | ||
| 8 | JENNISON ASSOCIATES LLC | 370,825 | 5,116,000 | 2.66% | ||
| 9 | PERCEPTIVE ADVISORS LLC | 176,000 | 2,443,000 | 1.27% | ||
| 10 | VANGUARD GROUP INC | 102,566 | 1,424,000 | 0.74% | ||
| 11 | GEODE CAPITAL MANAGEMENT, LLC | 40,761 | 565,000 | 0.29% | ||
| 12 | NORTHERN TRUST CORP | 12,266 | 170,000 | 0.09% | ||
| 13 | GOLDMAN SACHS GROUP INC | 12,161 | 169,000 | 0.09% | ||
| 14 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 10,790 | 150,000 | 0.08% | ||
| 15 | NORGES BANK | 3,999 | 56,000 | 0.03% | ||
| 16 | MORGAN STANLEY | 3,827 | 53,000 | 0.03% | ||
| 17 | UBS Group AG | 3,000 | 42,000 | 0.02% | ||
| 18 | BlackRock Fund Advisors | 1,642 | 23,000 | 0.01% | ||
| 19 | BANK OF AMERICA CORP /DE/ | 1,039 | 14,000 | 0.01% | ||
| 20 | Tower Research Capital LLC (TRC) | 779 | 11,000 | 0.01% | ||
| 21 | BLACKROCK ADVISORS LLC | 438 | 6,000 | 0.00% | ||
| 22 | ROYAL BANK OF CANADA | 300 | 4,000 | 0.00% | ||
| 23 | CITIGROUP INC | 12 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
