| 1 |
WELLINGTON MANAGEMENT GROUP LLP |
6,996,415 |
7,206,000 |
18.40% |
|
|
| 2 |
Broadfin Capital, LLC |
5,580,034 |
5,747,000 |
14.68% |
|
|
| 3 |
AWM Investment Company, Inc. |
5,419,074 |
5,582,000 |
14.26% |
|
|
| 4 |
GREAT POINT PARTNERS LLC |
4,011,511 |
4,132,000 |
10.55% |
|
|
| 5 |
FMR LLC |
4,000,000 |
4,120,000 |
10.52% |
|
|
| 6 |
Rock Springs Capital Management LP |
4,000,000 |
4,120,000 |
10.52% |
|
|
| 7 |
ACUTA CAPITAL PARTNERS, LLC |
2,886,731 |
2,973,000 |
7.59% |
|
|
| 8 |
SABBY MANAGEMENT, LLC |
1,149,394 |
1,184,000 |
3.02% |
|
|
| 9 |
VANGUARD GROUP INC |
698,121 |
720,000 |
1.84% |
|
|
| 10 |
Opus Point Partners Management, LLC |
650,000 |
670,000 |
1.71% |
|
|
| 11 |
RENAISSANCE TECHNOLOGIES LLC |
607,900 |
626,000 |
1.60% |
|
|
| 12 |
GOLDMAN SACHS GROUP INC |
312,524 |
322,000 |
0.82% |
|
|
| 13 |
EDMOND DE ROTHSCHILD HOLDING S.A. |
241,050 |
248,000 |
0.63% |
|
|
| 14 |
EDMOND DE ROTHSCHILD (SUISSE) S.A. |
241,050 |
248,000 |
0.63% |
|
|
| 15 |
MILLENNIUM MANAGEMENT LLC |
161,167 |
166,000 |
0.42% |
|
|
| 16 |
Sio Capital Management, LLC |
160,523 |
165,000 |
0.42% |
|
|
| 17 |
GEODE CAPITAL MANAGEMENT, LLC |
117,056 |
120,000 |
0.31% |
|
|
| 18 |
SHEPHERD KAPLAN KROCHUK, LLC |
109,525 |
113,000 |
0.29% |
|
|
| 19 |
BlackRock Fund Advisors |
82,041 |
85,000 |
0.22% |
|
|
| 20 |
GROUP ONE TRADING LLC |
74,313 |
77,000 |
0.20% |
|
|
| 21 |
DEUTSCHE BANK AG\ |
74,700 |
76,000 |
0.19% |
|
|
| 22 |
Psagot Value Holdings Ltd. |
71,000 |
73,000 |
0.19% |
|
|
| 23 |
DIMENSIONAL FUND ADVISORS LP |
55,388 |
57,000 |
0.15% |
|
|
| 24 |
NORTHERN TRUST CORP |
36,003 |
37,000 |
0.09% |
|
|
| 25 |
FNY Managed Accounts LLC |
30,000 |
30,900 |
0.08% |
|
|
| 26 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
28,687 |
30,000 |
0.08% |
|
|
| 27 |
NOMURA HOLDINGS INC |
27,000 |
28,000 |
0.07% |
|
|
| 28 |
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM |
22,656 |
23,000 |
0.06% |
|
|
| 29 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
21,700 |
22,000 |
0.06% |
Put |
|
| 30 |
First Allied Advisory Services, Inc. |
20,000 |
21,000 |
0.05% |
|
|
| 31 |
Rotella Capital Management, Inc. |
18,224 |
19,000 |
0.05% |
|
|
| 32 |
AMERIPRISE FINANCIAL INC |
17,000 |
18,000 |
0.05% |
|
|
| 33 |
A.R.T. Advisors, LLC |
18,287 |
18,000 |
0.05% |
|
|
| 34 |
Bank of New York Mellon Corp |
14,377 |
15,000 |
0.04% |
|
|
| 35 |
UBS Group AG |
12,833 |
13,000 |
0.03% |
|
|
| 36 |
Virtu KCG Holdings LLC |
11,966 |
12,000 |
0.03% |
|
|
| 37 |
BlackRock Investment Management, LLC |
10,113 |
10,000 |
0.03% |
|
|
| 38 |
BlackRock Institutional Trust Company, N.A. |
9,987 |
10,000 |
0.03% |
|
|
| 39 |
CITADEL ADVISORS LLC |
6,999 |
7,000 |
0.02% |
|
|
| 40 |
WELLS FARGO & COMPANY/MN |
5,000 |
5,000 |
0.01% |
|
|
| 41 |
Plante Moran Financial Advisors, LLC |
1,470 |
2,000 |
0.01% |
|
|
| 42 |
LADENBURG THALMANN FINANCIAL SERVICES INC. |
1,000 |
1,000 |
0.00% |
|
|
| 43 |
BANK OF AMERICA CORP /DE/ |
742 |
1,000 |
0.00% |
|
|
| 44 |
MORGAN STANLEY |
307 |
0 |
0.00% |
|
|
| 45 |
CITIGROUP INC |
294 |
0 |
0.00% |
|
|
| 46 |
D.A. DAVIDSON & CO. |
500 |
0 |
0.00% |
|
|
| 47 |
ADVANTAGE INVESTMENT MANAGEMENT, LLC |
250 |
0 |
0.00% |
|
|
