| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | BAUPOST GROUP LLC/MA | 2,226,839 | 7,393,000 | 33.94% | ||
| 2 | BVF INC/IL | 734,976 | 2,440,000 | 11.20% | ||
| 3 | SAMLYN CAPITAL, LLC | 616,040 | 2,046,000 | 9.39% | ||
| 4 | VANGUARD GROUP INC | 410,313 | 1,363,000 | 6.26% | ||
| 5 | MORGAN STANLEY | 389,102 | 1,293,000 | 5.94% | ||
| 6 | NEA Management Company, LLC | 370,900 | 1,231,000 | 5.65% | ||
| 7 | CREDIT SUISSE AG/ | 263,937 | 877,000 | 4.03% | ||
| 8 | BlackRock Institutional Trust Company, N.A. | 213,649 | 709,000 | 3.26% | ||
| 9 | BlackRock Fund Advisors | 197,602 | 656,000 | 3.01% | ||
| 10 | Palo Alto Investors LP | 167,302 | 555,000 | 2.55% | ||
| 11 | Rock Springs Capital Management LP | 165,300 | 549,000 | 2.52% | ||
| 12 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 141,800 | 471,000 | 2.16% | Put | |
| 13 | Rhenman & Partners Asset Management AB | 120,000 | 398,400 | 1.83% | ||
| 14 | GEODE CAPITAL MANAGEMENT, LLC | 65,690 | 218,000 | 1.00% | ||
| 15 | DEUTSCHE BANK AG\ | 62,874 | 208,000 | 0.95% | ||
| 16 | WOLVERINE ASSET MANAGEMENT LLC | 58,000 | 192,000 | 0.88% | Put | |
| 17 | Creative Planning | 51,663 | 172,000 | 0.79% | ||
| 18 | MILLENNIUM MANAGEMENT LLC | 41,735 | 139,000 | 0.64% | ||
| 19 | GOLDMAN SACHS GROUP INC | 34,057 | 113,000 | 0.52% | ||
| 20 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 31,320 | 104,000 | 0.48% | ||
| 21 | PDT Partners, LLC | 29,800 | 99,000 | 0.45% | ||
| 22 | Virtu KCG Holdings LLC | 23,622 | 78,000 | 0.36% | ||
| 23 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 20,143 | 67,000 | 0.31% | ||
| 24 | NORTHERN TRUST CORP | 20,127 | 66,000 | 0.30% | ||
| 25 | Bank of New York Mellon Corp | 15,685 | 52,000 | 0.24% | ||
| 26 | WELLS FARGO & COMPANY/MN | 14,930 | 49,000 | 0.22% | ||
| 27 | CQS Cayman LP | 11,300 | 38,000 | 0.17% | ||
| 28 | TWO SIGMA SECURITIES, LLC | 10,478 | 35,000 | 0.16% | ||
| 29 | Telemetry Investments, L.L.C. | 10,250 | 34,000 | 0.16% | ||
| 30 | Tower Research Capital LLC (TRC) | 5,466 | 18,000 | 0.08% | ||
| 31 | GROUP ONE TRADING LLC | 5,262 | 17,000 | 0.08% | ||
| 32 | CITIGROUP INC | 5,020 | 17,000 | 0.08% | Put | |
| 33 | CITIGROUP INC | 4,520 | 15,000 | 0.07% | Call | |
| 34 | UBS Group AG | 3,610 | 12,000 | 0.06% | ||
| 35 | CITIGROUP INC | 2,653 | 9,000 | 0.04% | ||
| 36 | ADVISOR GROUP, INC. | 2,732 | 9,000 | 0.04% | ||
| 37 | SIMPLEX TRADING, LLC | 2,455 | 8,000 | 0.04% | ||
| 38 | BLACKROCK ADVISORS LLC | 1,808 | 6,000 | 0.03% | ||
| 39 | BARCLAYS PLC | 1,450 | 5,000 | 0.02% | Put | |
| 40 | CUTLER GROUP LLC / CA | 978 | 3,000 | 0.01% | ||
| 41 | BARCLAYS PLC | 860 | 3,000 | 0.01% | Call | |
| 42 | Compagnie Lombard Odier SCmA | 1,000 | 3,000 | 0.01% | ||
| 43 | Allworth Financial LP | 500 | 2,000 | 0.01% | ||
| 44 | Creative Planning | 6,700 | 2,000 | 0.01% | Call | |
| 45 | ROYAL BANK OF CANADA | 690 | 2,000 | 0.01% | ||
| 46 | JPMORGAN CHASE & CO | 600 | 2,000 | 0.01% | ||
| 47 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 386 | 1,000 | 0.00% | ||
| 48 | JNBA Financial Advisors | 200 | 1,000 | 0.00% | ||
| 49 | SIGNATUREFD, LLC | 200 | 1,000 | 0.00% | ||
| 50 | ASSET PLANNING SERVICES, LTD. | 100 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
