| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | ABIOMED INC | 1,884,384 | 242,294,000 | 14.07% | ||
| 2 | UNITED THERAPEUTICS | 1,763,458 | 208,229,000 | 12.10% | ||
| 3 | BIOMARIN | 1,790,899 | 165,694,000 | 9.62% | ||
| 4 | CLOVIS ONCOLOGY INC | 3,804,088 | 137,137,000 | 7.97% | ||
| 5 | AMAG PHARMACEUTICALS INC COM | 3,326,720 | 81,538,000 | 4.74% | ||
| 6 | INSMED INC COM PAR .01 | 5,091,298 | 73,926,000 | 4.29% | ||
| 7 | CEMPRA INC | 2,844,483 | 68,836,000 | 4.00% | ||
| 8 | ALEXION PHARMACEUTIC | 561,700 | 68,831,000 | 4.00% | ||
| 9 | VANDA PHARMACEUTICALS INC COM | 4,110,708 | 68,402,000 | 3.97% | ||
| 10 | Wright Medical Group NV | 2,440,493 | 59,865,000 | 3.48% | ||
| 11 | PROTHENA CORP PLC | 934,455 | 56,039,000 | 3.26% | ||
| 12 | ZELTIQ AESTHETICS INCORPORATED | 1,414,563 | 55,479,000 | 3.22% | ||
| 13 | ACADIA PHARMACEUTICALS INC COM | 1,481,930 | 47,140,000 | 2.74% | ||
| 14 | AMICUS THERAPEUTICS INC | 5,685,388 | 42,072,000 | 2.44% | ||
| 15 | SAGE THERAPEUTICS | 902,051 | 41,539,000 | 2.41% | ||
| 16 | ARIAD PHARMACEUTICALS INC | 2,587,617 | 35,424,000 | 2.06% | ||
| 17 | CELGENE CORP | 292,700 | 30,596,000 | 1.78% | ||
| 18 | STAAR SURGICAL CO | 3,244,610 | 30,499,000 | 1.77% | ||
| 19 | KARYOPHARM THERAPEUTICS INC COM | 3,085,849 | 30,025,000 | 1.74% | ||
| 20 | EPIZYME INC COM | 2,814,540 | 27,695,000 | 1.61% | ||
| 21 | GILEAD SCIENCES INC | 318,400 | 25,192,000 | 1.46% | ||
| 22 | SHIRE PLC | 123,200 | 23,884,000 | 1.39% | ||
| 23 | Momenta Pharmaceuticals Inc | 1,650,876 | 19,299,000 | 1.12% | ||
| 24 | ENDO INTL | 945,330 | 19,048,000 | 1.11% | ||
| 25 | RIGEL PHARMACEUTICAL INC | 5,186,088 | 19,033,000 | 1.11% | ||
| 26 | EXACT SCIENCES CORP | 396,976 | 7,372,000 | 0.43% | ||
| 27 | ACELRX PHARMACEUTICALS INC | 1,634,608 | 6,359,000 | 0.37% | ||
| 28 | AIMMUNE THERAPEUTICS INC COM | 379,727 | 5,696,000 | 0.33% | ||
| 29 | Sunesis Pharmaceuticals, Inc. | 1,162,473 | 5,080,000 | 0.30% | ||
| 30 | ALIMERA SCIENCES INC | 3,013,793 | 4,491,000 | 0.26% | ||
| 31 | ALIGN TECHNOLOGY INC | 37,457 | 3,512,000 | 0.20% | ||
| 32 | IDERA PHARMACEUTICALS INC | 1,257,748 | 3,220,000 | 0.19% | ||
| 33 | Dicerna Pharmaceuticals | 267,890 | 1,575,000 | 0.09% | ||
| 34 | HISTOGENICS CORP | 454,545 | 1,459,000 | 0.08% | ||
| 35 | INTREXON CORP | 47,100 | 1,320,000 | 0.08% | ||
| 36 | CYTOKINETICS INC | 123,686 | 1,135,000 | 0.07% | ||
| 37 | SOPHIRIS BIO INC | 247,000 | 768,000 | 0.04% | ||
| 38 | ALCOBRA LTD | 272,788 | 674,000 | 0.04% | ||
| 39 | OREXIGEN THERAPEUTICS INC | 167,302 | 555,000 | 0.03% | ||
| 40 | ZOGENIX INC | 29,500 | 337,000 | 0.02% | ||
| 41 | UNIQURE NV | 20,453 | 156,000 | 0.01% | ||
| 42 | MARINUS PHARMACEUTICALS INC | 63,517 | 116,000 | 0.01% |
Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001306923-16-000052, filed 2016.11.14).
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
