| # | % | |||||
|---|---|---|---|---|---|---|
| 51 | SCHRODER INVESTMENT MANAGEMENT GROUP | 110,939 | 300,000 | 0.82% | ||
| 52 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 117,900 | 318,000 | 0.87% | ||
| 53 | DEUTSCHE BANK AG\ | 127,343 | 341,000 | 0.94% | ||
| 54 | GEODE CAPITAL MANAGEMENT, LLC | 135,256 | 365,000 | 1.00% | ||
| 55 | Rhenman & Partners Asset Management AB | 154,006 | 416,000 | 1.14% | ||
| 56 | JW Asset Management, LLC | 178,654 | 482,000 | 1.32% | ||
| 57 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 183,900 | 497,000 | 1.36% | ||
| 58 | AWM Investment Company, Inc. | 200,000 | 540,000 | 1.48% | ||
| 59 | NORTHERN TRUST CORP | 220,245 | 595,000 | 1.63% | ||
| 60 | Connor, Clark & Lunn Investment Management Ltd. | 229,350 | 619,000 | 1.70% | ||
| 61 | VHCP MANAGEMENT II, LLC | 280,000 | 756,000 | 2.07% | ||
| 62 | SABBY MANAGEMENT, LLC | 282,630 | 763,000 | 2.09% | ||
| 63 | MILLENNIUM MANAGEMENT LLC | 291,125 | 786,000 | 2.16% | ||
| 64 | PANAGORA ASSET MANAGEMENT INC | 296,583 | 801,000 | 2.20% | ||
| 65 | STATE STREET CORP | 332,173 | 899,000 | 2.47% | ||
| 66 | 683 Capital Management, LLC | 350,000 | 945,000 | 2.59% | ||
| 67 | CASDIN CAPITAL, LLC | 420,000 | 1,134,000 | 3.11% | ||
| 68 | PRIMECAP MANAGEMENT CO/CA/ | 440,400 | 1,189,000 | 3.26% | ||
| 69 | VANGUARD GROUP INC | 630,302 | 1,702,000 | 4.67% | ||
| 70 | EcoR1 Capital, LLC | 874,447 | 2,361,000 | 6.48% | ||
| 71 | Numeric Investors LLC | 1,087,967 | 2,938,000 | 8.06% | ||
| 72 | RENAISSANCE TECHNOLOGIES LLC | 1,141,977 | 3,083,000 | 8.46% | ||
| 73 | BlackRock Finance, Inc. | 1,406,468 | 3,798,000 | 10.42% | ||
| 74 | FMR LLC | 2,770,550 | 7,480,000 | 20.52% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
