| 1 |
FMR LLC |
2,770,550 |
7,480,000 |
20.52% |
|
|
| 2 |
BlackRock Finance, Inc. |
1,406,468 |
3,798,000 |
10.42% |
|
|
| 3 |
RENAISSANCE TECHNOLOGIES LLC |
1,141,977 |
3,083,000 |
8.46% |
|
|
| 4 |
Numeric Investors LLC |
1,087,967 |
2,938,000 |
8.06% |
|
|
| 5 |
EcoR1 Capital, LLC |
874,447 |
2,361,000 |
6.48% |
|
|
| 6 |
VANGUARD GROUP INC |
630,302 |
1,702,000 |
4.67% |
|
|
| 7 |
PRIMECAP MANAGEMENT CO/CA/ |
440,400 |
1,189,000 |
3.26% |
|
|
| 8 |
CASDIN CAPITAL, LLC |
420,000 |
1,134,000 |
3.11% |
|
|
| 9 |
683 Capital Management, LLC |
350,000 |
945,000 |
2.59% |
|
|
| 10 |
STATE STREET CORP |
332,173 |
899,000 |
2.47% |
|
|
| 11 |
PANAGORA ASSET MANAGEMENT INC |
296,583 |
801,000 |
2.20% |
|
|
| 12 |
MILLENNIUM MANAGEMENT LLC |
291,125 |
786,000 |
2.16% |
|
|
| 13 |
SABBY MANAGEMENT, LLC |
282,630 |
763,000 |
2.09% |
|
|
| 14 |
VHCP MANAGEMENT II, LLC |
280,000 |
756,000 |
2.07% |
|
|
| 15 |
Connor, Clark & Lunn Investment Management Ltd. |
229,350 |
619,000 |
1.70% |
|
|
| 16 |
NORTHERN TRUST CORP |
220,245 |
595,000 |
1.63% |
|
|
| 17 |
AWM Investment Company, Inc. |
200,000 |
540,000 |
1.48% |
|
|
| 18 |
BRIDGEWAY CAPITAL MANAGEMENT, LLC |
183,900 |
497,000 |
1.36% |
|
|
| 19 |
JW Asset Management, LLC |
178,654 |
482,000 |
1.32% |
|
|
| 20 |
Rhenman & Partners Asset Management AB |
154,006 |
416,000 |
1.14% |
|
|
| 21 |
GEODE CAPITAL MANAGEMENT, LLC |
135,256 |
365,000 |
1.00% |
|
|
| 22 |
DEUTSCHE BANK AG\ |
127,343 |
341,000 |
0.94% |
|
|
| 23 |
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM |
117,900 |
318,000 |
0.87% |
|
|
| 24 |
SCHRODER INVESTMENT MANAGEMENT GROUP |
110,939 |
300,000 |
0.82% |
|
|
| 25 |
DIMENSIONAL FUND ADVISORS LP |
109,121 |
295,000 |
0.81% |
|
|
| 26 |
Paloma Partners Management Co |
100,000 |
270,000 |
0.74% |
|
|
| 27 |
JPMORGAN CHASE & CO |
95,319 |
258,000 |
0.71% |
|
|
| 28 |
TFS CAPITAL LLC |
89,156 |
241,000 |
0.66% |
|
|
| 29 |
TIAA CREF INVESTMENT MANAGEMENT LLC |
73,534 |
199,000 |
0.55% |
|
|
| 30 |
Bank of New York Mellon Corp |
72,277 |
196,000 |
0.54% |
|
|
| 31 |
PARAMETRIC PORTFOLIO ASSOCIATES LLC |
53,218 |
144,000 |
0.39% |
|
|
| 32 |
TEACHERS ADVISORS, LLC |
48,297 |
130,000 |
0.36% |
|
|
| 33 |
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
47,237 |
128,000 |
0.35% |
|
|
| 34 |
GILDER GAGNON HOWE & CO LLC |
45,425 |
123,000 |
0.34% |
|
|
| 35 |
PDT Partners, LLC |
34,546 |
93,000 |
0.26% |
|
|
| 36 |
HIGHBRIDGE CAPITAL MANAGEMENT LLC |
33,170 |
90,000 |
0.25% |
|
|
| 37 |
MORGAN STANLEY |
29,916 |
81,000 |
0.22% |
|
|
| 38 |
RHUMBLINE ADVISERS |
28,704 |
78,000 |
0.21% |
|
|
| 39 |
CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
28,209 |
77,000 |
0.21% |
|
|
| 40 |
OXFORD ASSET MANAGEMENT LLP |
28,041 |
76,000 |
0.21% |
|
|
| 41 |
ALLIANCEBERNSTEIN L.P. |
24,300 |
66,000 |
0.18% |
|
|
| 42 |
JACOBS LEVY EQUITY MANAGEMENT, INC |
24,447 |
66,000 |
0.18% |
|
|
| 43 |
Marquette Asset Management, LLC |
23,746 |
64,000 |
0.18% |
|
|
| 44 |
Redmile Group, LLC |
22,236 |
60,000 |
0.16% |
|
|
| 45 |
D. E. Shaw & Co., Inc. |
18,315 |
49,000 |
0.13% |
|
|
| 46 |
NEW YORK STATE COMMON RETIREMENT FUND |
17,901 |
48,000 |
0.13% |
|
|
| 47 |
A.R.T. Advisors, LLC |
17,759 |
47,000 |
0.13% |
|
|
| 48 |
WEDBUSH SECURITIES INC |
17,500 |
47,000 |
0.13% |
|
|
| 49 |
R&F CAPITAL ADVISORS LP |
16,558 |
45,000 |
0.12% |
|
|
| 50 |
Nationwide Fund Advisors |
16,237 |
44,000 |
0.12% |
|
|
