| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | MPM ASSET MANAGEMENT LLC | 2,168,691 | 28,887,000 | 22.99% | ||
| 2 | FMR LLC | 2,094,464 | 27,898,000 | 22.21% | ||
| 3 | WELLINGTON MANAGEMENT GROUP LLP | 1,318,028 | 17,557,000 | 13.97% | ||
| 4 | ORBIMED ADVISORS LLC | 757,365 | 10,088,000 | 8.03% | ||
| 5 | EcoR1 Capital, LLC | 510,829 | 6,804,000 | 5.42% | ||
| 6 | JENNISON ASSOCIATES LLC | 460,892 | 5,978,000 | 4.76% | ||
| 7 | BLACKROCK ADVISORS LLC | 308,693 | 4,112,000 | 3.27% | ||
| 8 | TIVERTON ASSET MANAGEMENT LLC | 288,750 | 3,846,000 | 3.06% | ||
| 9 | Redmile Group, LLC | 263,000 | 3,503,000 | 2.79% | ||
| 10 | BOXER CAPITAL, LLC | 234,220 | 3,120,000 | 2.48% | ||
| 11 | Cormorant Asset Management, LP | 214,419 | 2,856,000 | 2.27% | ||
| 12 | BlackRock Group LTD | 178,626 | 2,379,000 | 1.89% | ||
| 13 | Alyeska Investment Group, L.P. | 175,000 | 2,331,000 | 1.86% | ||
| 14 | ArrowMark Colorado Holdings LLC | 149,931 | 1,997,000 | 1.59% | ||
| 15 | UNITED SERVICES AUTOMOBILE ASSOCIATION | 57,990 | 772,000 | 0.61% | ||
| 16 | GENERAL ELECTRIC CO | 53,646 | 715,000 | 0.57% | ||
| 17 | MILLENNIUM MANAGEMENT LLC | 47,114 | 628,000 | 0.50% | ||
| 18 | BlackRock Finance, Inc. | 44,595 | 594,000 | 0.47% | ||
| 19 | KORNITZER CAPITAL MANAGEMENT INC /KS | 40,000 | 533,000 | 0.42% | ||
| 20 | GOLDMAN SACHS GROUP INC | 26,500 | 353,000 | 0.28% | ||
| 21 | NORGES BANK | 25,000 | 333,000 | 0.27% | ||
| 22 | BlackRock Investment Management, LLC | 18,086 | 241,000 | 0.19% | ||
| 23 | MORGAN STANLEY | 3,479 | 46,000 | 0.04% | ||
| 24 | DEUTSCHE BANK AG\ | 2,989 | 39,000 | 0.03% | ||
| 25 | Tower Research Capital LLC (TRC) | 863 | 11,000 | 0.01% | ||
| 26 | BlackRock Institutional Trust Company, N.A. | 698 | 9,000 | 0.01% | ||
| 27 | Catalyst Capital Advisors LLC | 182 | 2,000 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
