| 1 |
WELLINGTON MANAGEMENT GROUP LLP |
2,344,648 |
16,811,000 |
21.08% |
|
|
| 2 |
MPM ASSET MANAGEMENT LLC |
2,168,691 |
15,550,000 |
19.50% |
|
|
| 3 |
FMR LLC |
1,480,047 |
10,612,000 |
13.31% |
|
|
| 4 |
BLACKROCK ADVISORS LLC |
1,027,672 |
7,369,000 |
9.24% |
|
|
| 5 |
ORBIMED ADVISORS LLC |
757,365 |
5,430,000 |
6.81% |
|
|
| 6 |
VANGUARD GROUP INC |
390,402 |
2,799,000 |
3.51% |
|
|
| 7 |
EcoR1 Capital, LLC |
273,862 |
1,964,000 |
2.46% |
|
|
| 8 |
ArrowMark Colorado Holdings LLC |
266,164 |
1,908,000 |
2.39% |
|
|
| 9 |
Cormorant Asset Management, LP |
240,403 |
1,724,000 |
2.16% |
|
|
| 10 |
BOXER CAPITAL, LLC |
234,220 |
1,679,000 |
2.11% |
|
|
| 11 |
Alyeska Investment Group, L.P. |
225,000 |
1,613,000 |
2.02% |
|
|
| 12 |
EverPoint Asset Management, LLC |
200,000 |
1,434,000 |
1.80% |
|
|
| 13 |
BlackRock Group LTD |
175,926 |
1,261,000 |
1.58% |
|
|
| 14 |
SPHERA FUNDS MANAGEMENT LTD. |
166,310 |
1,192,000 |
1.49% |
|
|
| 15 |
BlackRock Fund Advisors |
151,781 |
1,088,000 |
1.36% |
|
|
| 16 |
UNITED SERVICES AUTOMOBILE ASSOCIATION |
107,680 |
772,000 |
0.97% |
|
|
| 17 |
MILLENNIUM MANAGEMENT LLC |
100,065 |
717,000 |
0.90% |
|
|
| 18 |
JENNISON ASSOCIATES LLC |
93,783 |
672,000 |
0.84% |
|
|
| 19 |
GEODE CAPITAL MANAGEMENT, LLC |
89,552 |
642,000 |
0.80% |
|
|
| 20 |
TIVERTON ASSET MANAGEMENT LLC |
83,172 |
596,000 |
0.75% |
|
|
| 21 |
NORTHERN TRUST CORP |
60,102 |
431,000 |
0.54% |
|
|
| 22 |
STATE STREET CORP |
58,921 |
422,000 |
0.53% |
|
|
| 23 |
BlackRock Finance, Inc. |
44,851 |
322,000 |
0.40% |
|
|
| 24 |
MORGAN STANLEY |
38,828 |
278,000 |
0.35% |
|
|
| 25 |
KORNITZER CAPITAL MANAGEMENT INC /KS |
36,900 |
265,000 |
0.33% |
|
|
| 26 |
BlackRock Investment Management, LLC |
36,068 |
259,000 |
0.32% |
|
|
| 27 |
MEADOW CREEK INVESTMENT MANAGEMENT LLC |
34,510 |
247,000 |
0.31% |
|
|
| 28 |
ELKFORK PARTNERS LLC |
28,420 |
204,000 |
0.26% |
|
|
| 29 |
BlackRock Institutional Trust Company, N.A. |
26,166 |
188,000 |
0.24% |
|
|
| 30 |
PARAMETRIC PORTFOLIO ASSOCIATES LLC |
23,127 |
166,000 |
0.21% |
|
|
| 31 |
GLEN HARBOR CAPITAL MANAGEMENT LLC |
22,330 |
160,000 |
0.20% |
|
|
| 32 |
Bank of New York Mellon Corp |
20,366 |
146,000 |
0.18% |
|
|
| 33 |
TIAA CREF INVESTMENT MANAGEMENT LLC |
16,833 |
121,000 |
0.15% |
|
|
| 34 |
TFS CAPITAL LLC |
16,130 |
116,000 |
0.15% |
|
|
| 35 |
NEUBURGH ADVISERS LLC |
16,240 |
116,000 |
0.15% |
|
|
| 36 |
CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
10,100 |
73,000 |
0.09% |
|
|
| 37 |
JPMORGAN CHASE & CO |
10,185 |
73,000 |
0.09% |
|
|
| 38 |
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
9,787 |
70,000 |
0.09% |
|
|
| 39 |
TEACHERS ADVISORS, LLC |
7,360 |
53,000 |
0.07% |
|
|
| 40 |
BARCLAYS PLC |
5,807 |
41,000 |
0.05% |
|
|
| 41 |
Tower Research Capital LLC (TRC) |
3,547 |
26,000 |
0.03% |
|
|
| 42 |
Nationwide Fund Advisors |
2,850 |
20,000 |
0.03% |
|
|
| 43 |
DEUTSCHE BANK AG\ |
2,733 |
19,000 |
0.02% |
|
|
| 44 |
Cubist Systematic Strategies, LLC |
2,666 |
19,000 |
0.02% |
|
|
| 45 |
AMERICAN INTERNATIONAL GROUP, INC. |
2,710 |
19,000 |
0.02% |
|
|
| 46 |
NEW YORK STATE COMMON RETIREMENT FUND |
1,800 |
13,000 |
0.02% |
|
|
| 47 |
WELLS FARGO & COMPANY/MN |
1,648 |
12,000 |
0.02% |
|
|
| 48 |
STRS OHIO |
1,500 |
10,000 |
0.01% |
|
|
| 49 |
Legal & General Group Plc |
1,107 |
8,000 |
0.01% |
|
|
| 50 |
First Personal Financial Services |
1,069 |
8,000 |
0.01% |
|
|
