| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | MPM ASSET MANAGEMENT LLC | 2,168,691 | 21,362,000 | 20.98% | ||
| 2 | FMR LLC | 2,094,464 | 20,630,000 | 20.26% | ||
| 3 | WELLINGTON MANAGEMENT GROUP LLP | 1,294,076 | 12,746,000 | 12.52% | ||
| 4 | BLACKROCK ADVISORS LLC | 1,026,902 | 10,115,000 | 9.94% | ||
| 5 | ORBIMED ADVISORS LLC | 757,365 | 7,460,000 | 7.33% | ||
| 6 | JENNISON ASSOCIATES LLC | 537,545 | 5,247,000 | 5.15% | ||
| 7 | EcoR1 Capital, LLC | 357,365 | 3,520,000 | 3.46% | ||
| 8 | Redmile Group, LLC | 250,830 | 2,471,000 | 2.43% | ||
| 9 | BOXER CAPITAL, LLC | 234,220 | 2,307,000 | 2.27% | ||
| 10 | Cormorant Asset Management, LP | 214,419 | 2,112,000 | 2.07% | ||
| 11 | BlackRock Group LTD | 178,626 | 1,759,000 | 1.73% | ||
| 12 | ArrowMark Colorado Holdings LLC | 172,633 | 1,700,000 | 1.67% | ||
| 13 | VANGUARD GROUP INC | 169,901 | 1,674,000 | 1.64% | ||
| 14 | Alyeska Investment Group, L.P. | 125,000 | 1,231,000 | 1.21% | ||
| 15 | BlackRock Fund Advisors | 123,672 | 1,218,000 | 1.20% | ||
| 16 | TIVERTON ASSET MANAGEMENT LLC | 8,612 | 760,000 | 0.75% | ||
| 17 | UNITED SERVICES AUTOMOBILE ASSOCIATION | 56,400 | 556,000 | 0.55% | ||
| 18 | GENERAL ELECTRIC CO | 53,646 | 528,000 | 0.52% | ||
| 19 | NORTHERN TRUST CORP | 50,215 | 495,000 | 0.49% | ||
| 20 | STATE STREET CORP | 45,546 | 448,000 | 0.44% | ||
| 21 | KORNITZER CAPITAL MANAGEMENT INC /KS | 45,500 | 448,000 | 0.44% | ||
| 22 | BlackRock Finance, Inc. | 44,851 | 442,000 | 0.43% | ||
| 23 | BlackRock Institutional Trust Company, N.A. | 43,216 | 426,000 | 0.42% | ||
| 24 | BlackRock Investment Management, LLC | 36,068 | 355,000 | 0.35% | ||
| 25 | GEODE CAPITAL MANAGEMENT, LLC | 29,979 | 295,000 | 0.29% | ||
| 26 | ALPS ADVISORS INC | 24,979 | 246,000 | 0.24% | ||
| 27 | NORGES BANK | 24,768 | 244,000 | 0.24% | ||
| 28 | PARAMETRIC PORTFOLIO ASSOCIATES LLC | 23,293 | 229,000 | 0.22% | ||
| 29 | MILLENNIUM MANAGEMENT LLC | 13,879 | 137,000 | 0.13% | ||
| 30 | TIAA CREF INVESTMENT MANAGEMENT LLC | 11,299 | 111,000 | 0.11% | ||
| 31 | NEW YORK STATE COMMON RETIREMENT FUND | 11,100 | 109,000 | 0.11% | ||
| 32 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 10,100 | 100,000 | 0.10% | ||
| 33 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 9,887 | 97,000 | 0.10% | ||
| 34 | DEUTSCHE BANK AG\ | 5,573 | 54,000 | 0.05% | ||
| 35 | TEACHERS ADVISORS, LLC | 4,911 | 48,000 | 0.05% | ||
| 36 | Nationwide Fund Advisors | 2,850 | 28,000 | 0.03% | ||
| 37 | AMERICAN INTERNATIONAL GROUP, INC. | 2,714 | 26,733 | 0.03% | ||
| 38 | MORGAN STANLEY | 2,118 | 20,000 | 0.02% | ||
| 39 | STRS OHIO | 1,600 | 15,000 | 0.01% | ||
| 40 | UBS Group AG | 871 | 9,000 | 0.01% | ||
| 41 | BARCLAYS PLC | 798 | 8,000 | 0.01% | ||
| 42 | JPMORGAN CHASE & CO | 505 | 5,000 | 0.00% | ||
| 43 | CITIGROUP INC | 471 | 5,000 | 0.00% | ||
| 44 | Catalyst Capital Advisors LLC | 182 | 2,000 | 0.00% | ||
| 45 | Tower Research Capital LLC (TRC) | 253 | 2,000 | 0.00% | ||
| 46 | BNP PARIBAS FINANCIAL MARKETS | 186 | 1,832 | 0.00% | ||
| 47 | WOLVERINE TRADING LP /BD | 179 | 1,752 | 0.00% | ||
| 48 | BANK OF AMERICA CORP /DE/ | 89 | 1,000 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
