| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Cormorant Asset Management, LP | 3,804,027 | 46,637,000 | 22.09% | ||
| 2 | NEA Management Company, LLC | 3,556,778 | 43,606,000 | 20.66% | ||
| 3 | FMR LLC | 2,206,868 | 27,056,000 | 12.82% | ||
| 4 | JENNISON ASSOCIATES LLC | 2,135,708 | 26,184,000 | 12.40% | ||
| 5 | HILLHOUSE INVESTMENT MANAGEMENT, LTD. | 865,923 | 10,616,000 | 5.03% | ||
| 6 | FIL Ltd | 652,316 | 7,997,000 | 3.79% | ||
| 7 | Rock Springs Capital Management LP | 450,000 | 5,517,000 | 2.61% | ||
| 8 | MARSHALL WACE, LLP | 442,836 | 5,429,000 | 2.57% | ||
| 9 | VANGUARD GROUP INC | 432,183 | 5,299,000 | 2.51% | ||
| 10 | FRANKLIN RESOURCES INC | 322,400 | 3,953,000 | 1.87% | ||
| 11 | MILLENNIUM MANAGEMENT LLC | 289,002 | 3,543,000 | 1.68% | ||
| 12 | BlackRock Fund Advisors | 253,809 | 3,112,000 | 1.47% | ||
| 13 | EVENTIDE ASSET MANAGEMENT, LLC | 220,000 | 2,697,000 | 1.28% | ||
| 14 | PRICE T ROWE ASSOCIATES INC /MD/ | 212,817 | 2,609,000 | 1.24% | ||
| 15 | DEERFIELD MANAGEMENT COMPANY, L.P. | 186,000 | 2,280,000 | 1.08% | ||
| 16 | JPMORGAN CHASE & CO | 171,557 | 2,103,000 | 1.00% | ||
| 17 | Opaleye Management Inc. | 150,000 | 1,839,000 | 0.87% | ||
| 18 | NORTHERN TRUST CORP | 103,524 | 1,269,000 | 0.60% | ||
| 19 | BALYASNY ASSET MANAGEMENT L.P. | 95,855 | 1,175,000 | 0.56% | ||
| 20 | GEODE CAPITAL MANAGEMENT, LLC | 89,565 | 1,098,000 | 0.52% | ||
| 21 | STATE STREET CORP | 86,471 | 1,059,000 | 0.50% | ||
| 22 | BlackRock Institutional Trust Company, N.A. | 55,270 | 678,000 | 0.32% | ||
| 23 | Candriam S.C.A. | 45,000 | 552,000 | 0.26% | ||
| 24 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 41,200 | 505,000 | 0.24% | ||
| 25 | Squarepoint Ops LLC | 39,299 | 482,000 | 0.23% | ||
| 26 | MORGAN STANLEY | 35,745 | 439,000 | 0.21% | ||
| 27 | BlackRock Investment Management, LLC | 33,673 | 413,000 | 0.20% | ||
| 28 | Bank of New York Mellon Corp | 29,811 | 365,000 | 0.17% | ||
| 29 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 28,300 | 347,000 | 0.16% | ||
| 30 | TIAA CREF INVESTMENT MANAGEMENT LLC | 26,901 | 330,000 | 0.16% | ||
| 31 | VIRTUS ETF ADVISERS LLC | 24,169 | 296,000 | 0.14% | ||
| 32 | TFS CAPITAL LLC | 20,078 | 246,000 | 0.12% | ||
| 33 | Trexquant Investment LP | 19,600 | 240,000 | 0.11% | ||
| 34 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 16,483 | 202,000 | 0.10% | ||
| 35 | TEACHERS ADVISORS, LLC | 12,617 | 155,000 | 0.07% | ||
| 36 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 10,141 | 124,000 | 0.06% | ||
| 37 | CITIGROUP INC | 8,046 | 99,000 | 0.05% | ||
| 38 | NEW YORK STATE COMMON RETIREMENT FUND | 8,100 | 99,000 | 0.05% | ||
| 39 | ClariVest Asset Management LLC | 6,040 | 74,000 | 0.04% | ||
| 40 | Nationwide Fund Advisors | 5,471 | 67,000 | 0.03% | ||
| 41 | STRS OHIO | 5,000 | 61,000 | 0.03% | ||
| 42 | DEUTSCHE BANK AG\ | 4,945 | 59,000 | 0.03% | ||
| 43 | AMERICAN INTERNATIONAL GROUP, INC. | 3,641 | 45,000 | 0.02% | ||
| 44 | BLACKROCK ADVISORS LLC | 2,894 | 35,000 | 0.02% | ||
| 45 | WELLS FARGO & COMPANY/MN | 2,180 | 27,000 | 0.01% | ||
| 46 | Creative Planning | 2,000 | 25,000 | 0.01% | ||
| 47 | Legal & General Group Plc | 1,498 | 18,000 | 0.01% | ||
| 48 | UBS Group AG | 1,255 | 15,000 | 0.01% | ||
| 49 | BANK OF AMERICA CORP /DE/ | 1,098 | 13,000 | 0.01% | ||
| 50 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 622 | 8,000 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
