| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | PROTEOSTASIS THERAPEUTICS IN | 3,804,027 | 46,637,000 | 6.29% | ||
| 2 | Theravance Biopharma Inc | 1,425,000 | 45,429,000 | 6.12% | ||
| 3 | NEVRO CORP | 601,044 | 43,672,000 | 5.89% | ||
| 4 | ALDER BIOPHARMACEUTICALS INC | 1,581,604 | 32,897,000 | 4.43% | ||
| 5 | EAGLE PHARMACEUTICALS INC COM | 410,000 | 32,529,000 | 4.38% | ||
| 6 | MINERVA NEUROSCIENCES INC COM | 2,652,436 | 31,166,000 | 4.20% | ||
| 7 | ARDELYX INC COM | 2,071,964 | 29,422,000 | 3.97% | ||
| 8 | ACLARIS THERAPEUTICS INC COM | 976,286 | 26,496,000 | 3.57% | ||
| 9 | HERON THERAPEUTICS INC | 1,951,263 | 25,562,000 | 3.45% | ||
| 10 | BLUEPRINT MEDICINES CORP COM | 841,752 | 23,611,000 | 3.18% | ||
| 11 | GALAPAGOS NV | 334,044 | 21,409,000 | 2.89% | ||
| 12 | CORBUS PHARMACEUTICALS HLDGS COM | 2,500,000 | 21,125,000 | 2.85% | ||
| 13 | Clearside Biomedical Inc | 2,333,333 | 20,860,000 | 2.81% | ||
| 14 | MYOKARDIA INC | 1,445,090 | 18,714,000 | 2.52% | ||
| 15 | Protagonist Therapeutics, Inc. | 720,000 | 15,833,000 | 2.13% | ||
| 16 | COHERUS BIOSCIENCES INC COM | 519,090 | 14,612,000 | 1.97% | ||
| 17 | QUOTIENT LTD | 2,940,000 | 14,230,000 | 1.92% | ||
| 18 | NEUROCRINE BIOSCIE COM USD0.001 | 359,000 | 13,893,000 | 1.87% | ||
| 19 | WAVE LIFE SCIENCES LTD | 507,907 | 13,282,000 | 1.79% | ||
| 20 | CHINA BIOLOGIC PRODS INC | 112,867 | 12,135,000 | 1.64% | ||
| 21 | PORTOLA PHARMACEUTICALS INC | 537,000 | 12,050,000 | 1.62% | ||
| 22 | INC Research Holdings Inc | 200,000 | 10,520,000 | 1.42% | ||
| 23 | ARRAY BIOPHARMA INC COM | 1,150,000 | 10,109,000 | 1.36% | ||
| 24 | FULGENT GENETICS INC | 857,663 | 9,923,000 | 1.34% | ||
| 25 | OMEROS CORP | 975,000 | 9,672,000 | 1.30% | ||
| 26 | SORRENTO THERAPEUTICS INC COM NEW | 1,909,000 | 9,354,000 | 1.26% | ||
| 27 | SYNERGY PHARMACEUTICALS DEL COM NEW | 1,500,000 | 9,135,000 | 1.23% | ||
| 28 | Audentes Therapeutics, Inc. | 449,660 | 8,215,000 | 1.11% | ||
| 29 | ULTRAGENYX PHARMACEUTICAL INC COM | 110,842 | 7,793,000 | 1.05% | ||
| 30 | ZYNERBA PHARMACEUTICALS INC | 480,501 | 7,491,000 | 1.01% | ||
| 31 | Curis, Inc | 2,410,900 | 7,426,000 | 1.00% | ||
| 32 | COLLEGIUM PHARMACEUTICAL INC COM | 455,515 | 7,092,000 | 0.96% | ||
| 33 | GEMPHIRE THERAPEUTICS INC | 900,000 | 7,056,000 | 0.95% | ||
| 34 | RIGEL PHARMACEUTICAL INC | 2,868,700 | 6,828,000 | 0.92% | ||
| 35 | CONTRAFECT CORP COM | 3,842,966 | 6,725,000 | 0.91% | ||
| 36 | AGENUS INC | 1,421,000 | 5,855,000 | 0.79% | ||
| 37 | PFENEX INC COM | 632,559 | 5,737,000 | 0.77% | ||
| 38 | CONCERT PHARMACEUTICALS INC COM | 538,422 | 5,540,000 | 0.75% | ||
| 39 | DEXCOM | 90,000 | 5,373,000 | 0.72% | ||
| 40 | DERMIRA INC | 172,083 | 5,219,000 | 0.70% | ||
| 41 | FORWARD PHARMA A/S | 339,175 | 5,091,000 | 0.69% | ||
| 42 | SOCIETAL CDMO INC | 603,000 | 4,860,000 | 0.66% | ||
| 43 | Intec Pharma Ltd | 809,804 | 4,616,000 | 0.62% | ||
| 44 | INVUITY INC | 767,466 | 4,413,000 | 0.59% | ||
| 45 | CYTOMX THERAPEUTICS INC COM | 371,636 | 4,084,000 | 0.55% | ||
| 46 | Sunesis Pharmaceuticals, Inc. | 1,000,000 | 3,620,000 | 0.49% | ||
| 47 | ADVANCED ACCELERATOR APPLIC | 124,220 | 3,324,000 | 0.45% | ||
| 48 | Ascendis Pharma | 162,254 | 3,284,000 | 0.44% | ||
| 49 | ACCELERON PHARMA | 127,451 | 3,253,000 | 0.44% | ||
| 50 | Agile Therapeutics, Inc. | 563,880 | 3,214,000 | 0.43% |
Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001583977-17-000002, filed 2017.02.14).
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
