| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 3,268,521 | 43,079,000 | 21.12% | ||
| 2 | Omega Fund Management, LLC | 2,645,558 | 34,868,000 | 17.09% | ||
| 3 | FRANKLIN RESOURCES INC | 2,400,000 | 31,632,000 | 15.51% | ||
| 4 | FEDERATED HERMES, INC. | 2,051,463 | 27,038,000 | 13.25% | ||
| 5 | Broadfin Capital, LLC | 1,134,750 | 14,956,000 | 7.33% | ||
| 6 | WASATCH ADVISORS LP | 478,822 | 6,311,000 | 3.09% | ||
| 7 | DEERFIELD MANAGEMENT COMPANY, L.P. | 477,123 | 6,288,000 | 3.08% | ||
| 8 | Avoro Capital Advisors LLC | 440,606 | 5,807,000 | 2.85% | ||
| 9 | VANGUARD GROUP INC | 337,822 | 4,452,000 | 2.18% | ||
| 10 | WALL STREET ASSOCIATES | 331,100 | 4,364,000 | 2.14% | ||
| 11 | SPHERA FUNDS MANAGEMENT LTD. | 325,000 | 4,284,000 | 2.10% | ||
| 12 | Rock Springs Capital Management LP | 300,000 | 3,954,000 | 1.94% | ||
| 13 | TIVERTON ASSET MANAGEMENT LLC | 255,000 | 3,361,000 | 1.65% | ||
| 14 | HighTower Advisors, LLC | 184,328 | 2,429,000 | 1.19% | ||
| 15 | EMERALD ADVISERS, LLC | 128,430 | 1,693,000 | 0.83% | ||
| 16 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 99,700 | 1,314,000 | 0.64% | ||
| 17 | BlackRock Institutional Trust Company, N.A. | 89,171 | 1,175,000 | 0.58% | ||
| 18 | HAP Trading, LLC | 60,000 | 791,000 | 0.39% | ||
| 19 | GEODE CAPITAL MANAGEMENT, LLC | 56,880 | 749,000 | 0.37% | ||
| 20 | Janney Montgomery Scott LLC | 56,710 | 747,000 | 0.37% | ||
| 21 | D. E. Shaw & Co., Inc. | 35,647 | 470,000 | 0.23% | ||
| 22 | RENAISSANCE TECHNOLOGIES LLC | 31,800 | 419,000 | 0.21% | ||
| 23 | BlackRock Fund Advisors | 30,620 | 404,000 | 0.20% | ||
| 24 | TFS CAPITAL LLC | 30,461 | 401,000 | 0.20% | ||
| 25 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 28,500 | 376,000 | 0.18% | ||
| 26 | Alyeska Investment Group, L.P. | 27,518 | 363,000 | 0.18% | ||
| 27 | NORTHERN TRUST CORP | 26,233 | 346,000 | 0.17% | ||
| 28 | MILLENNIUM MANAGEMENT LLC | 25,310 | 334,000 | 0.16% | ||
| 29 | KEYBANK NATIONAL ASSOCIATION/OH | 24,372 | 321,000 | 0.16% | ||
| 30 | CITADEL ADVISORS LLC | 18,228 | 240,000 | 0.12% | ||
| 31 | DEUTSCHE BANK AG\ | 17,400 | 229,000 | 0.11% | ||
| 32 | APIS CAPITAL ADVISORS, LLC | 16,000 | 211,000 | 0.10% | ||
| 33 | Bank of New York Mellon Corp | 12,352 | 163,000 | 0.08% | ||
| 34 | ELLINGTON MANAGEMENT GROUP LLC | 11,328 | 149,000 | 0.07% | ||
| 35 | Brandywine Global Investment Management, LLC | 10,100 | 134,000 | 0.07% | ||
| 36 | SONORA INVESTMENT MANAGEMENT, LLC | 3,500 | 46,000 | 0.02% | ||
| 37 | BlackRock Investment Management, LLC | 2,308 | 30,000 | 0.01% | ||
| 38 | WELLS FARGO & COMPANY/MN | 2,019 | 27,000 | 0.01% | ||
| 39 | ROYAL BANK OF CANADA | 1,396 | 18,000 | 0.01% | ||
| 40 | MORGAN STANLEY | 1,150 | 15,000 | 0.01% | ||
| 41 | UBS Group AG | 174 | 2,000 | 0.00% | ||
| 42 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 125 | 2,000 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
