| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 4,594,240 | 260,034,000 | 17.31% | ||
| 2 | Capital Research Global Investors | 3,826,276 | 216,567,000 | 14.42% | ||
| 3 | TPG Group Holdings (SBS) Advisors, Inc. | 2,596,420 | 146,957,000 | 9.78% | ||
| 4 | COLUMBIA WANGER ASSET MANAGEMENT LLC | 1,791,082 | 101,375,000 | 6.75% | ||
| 5 | PRICE T ROWE ASSOCIATES INC /MD/ | 1,316,890 | 74,536,000 | 4.96% | ||
| 6 | VANGUARD GROUP INC | 1,090,962 | 61,748,000 | 4.11% | ||
| 7 | WELLINGTON MANAGEMENT GROUP LLP | 1,075,728 | 60,886,000 | 4.05% | ||
| 8 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 1,050,000 | 59,430,000 | 3.96% | ||
| 9 | FIL Ltd | 1,034,028 | 58,526,000 | 3.90% | ||
| 10 | JENNISON ASSOCIATES LLC | 758,566 | 42,935,000 | 2.86% | ||
| 11 | LORD, ABBETT & CO. LLC | 577,631 | 32,694,000 | 2.18% | ||
| 12 | Visium Asset Management, LP | 576,535 | 32,632,000 | 2.17% | ||
| 13 | BlackRock Institutional Trust Company, N.A. | 467,196 | 26,443,000 | 1.76% | ||
| 14 | BLACKROCK ADVISORS LLC | 436,653 | 24,715,000 | 1.65% | ||
| 15 | STATE STREET CORP | 378,865 | 21,445,000 | 1.43% | ||
| 16 | Capital World Investors | 361,987 | 20,488,000 | 1.36% | ||
| 17 | OppenheimerFunds, Inc. | 341,118 | 19,308,000 | 1.29% | ||
| 18 | ALLIANCEBERNSTEIN L.P. | 309,008 | 17,490,000 | 1.16% | ||
| 19 | FEDERATED HERMES, INC. | 288,900 | 16,352,000 | 1.09% | ||
| 20 | FRANKLIN RESOURCES INC | 220,800 | 12,497,000 | 0.83% | ||
| 21 | RS INVESTMENT MANAGEMENT CO LLC | 210,441 | 11,911,000 | 0.79% | ||
| 22 | CITADEL ADVISORS LLC | 208,743 | 11,815,000 | 0.79% | ||
| 23 | GOLDMAN SACHS GROUP INC | 208,073 | 11,777,000 | 0.78% | ||
| 24 | JPMORGAN CHASE & CO | 195,500 | 11,065,000 | 0.74% | ||
| 25 | BlackRock Fund Advisors | 151,106 | 8,553,000 | 0.57% | ||
| 26 | BAKER BROS. ADVISORS LP | 150,000 | 8,490,000 | 0.57% | ||
| 27 | COWEN INC. | 148,932 | 8,430,000 | 0.56% | ||
| 28 | Weiss Multi-Strategy Advisers LLC | 141,432 | 8,005,000 | 0.53% | ||
| 29 | GEODE CAPITAL MANAGEMENT, LLC | 125,156 | 7,083,000 | 0.47% | ||
| 30 | Cormorant Asset Management, LP | 120,000 | 6,792,000 | 0.45% | ||
| 31 | Cupps Capital Management, LLC | 111,920 | 6,334,000 | 0.42% | ||
| 32 | NORTHERN TRUST CORP | 104,557 | 5,917,000 | 0.39% | ||
| 33 | BlackRock Group LTD | 98,894 | 5,597,000 | 0.37% | ||
| 34 | Bank of New York Mellon Corp | 92,384 | 5,229,000 | 0.35% | ||
| 35 | Opaleye Management Inc. | 85,000 | 4,811,000 | 0.32% | ||
| 36 | MORGAN STANLEY | 69,380 | 3,926,000 | 0.26% | ||
| 37 | Rock Springs Capital Management LP | 67,500 | 3,821,000 | 0.25% | ||
| 38 | GUGGENHEIM CAPITAL LLC | 67,043 | 3,795,000 | 0.25% | ||
| 39 | PUTNAM INVESTMENTS LLC | 64,680 | 3,661,000 | 0.24% | ||
| 40 | AXA S.A. | 62,011 | 3,510,000 | 0.23% | ||
| 41 | DRIEHAUS CAPITAL MANAGEMENT LLC | 61,146 | 3,461,000 | 0.23% | ||
| 42 | Iguana Healthcare Management, LLC | 57,500 | 3,255,000 | 0.22% | ||
| 43 | EVENTIDE ASSET MANAGEMENT, LLC | 52,600 | 2,977,000 | 0.20% | ||
| 44 | TCW GROUP INC | 47,682 | 2,698,000 | 0.18% | ||
| 45 | Nationwide Fund Advisors | 46,547 | 2,635,000 | 0.18% | ||
| 46 | Zweig-DiMenna Associates LLC | 46,482 | 2,631,000 | 0.18% | ||
| 47 | BlackRock Investment Management, LLC | 46,424 | 2,628,000 | 0.17% | ||
| 48 | AMERIPRISE FINANCIAL INC | 46,301 | 2,620,000 | 0.17% | ||
| 49 | MASON STREET ADVISORS, LLC | 44,630 | 2,526,000 | 0.17% | ||
| 50 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 43,600 | 2,468,000 | 0.16% | Call |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
