| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 5,847,783 | 286,015,000 | 15.68% | ||
| 2 | Capital Research Global Investors | 4,778,169 | 233,700,000 | 12.81% | ||
| 3 | WELLINGTON MANAGEMENT GROUP LLP | 4,188,184 | 204,844,000 | 11.23% | ||
| 4 | VANGUARD GROUP INC | 2,589,718 | 126,664,000 | 6.95% | ||
| 5 | PRICE T ROWE ASSOCIATES INC /MD/ | 1,591,977 | 77,864,000 | 4.27% | ||
| 6 | BlackRock Fund Advisors | 1,390,985 | 68,033,000 | 3.73% | ||
| 7 | WELLS FARGO & COMPANY/MN | 1,348,155 | 65,939,000 | 3.62% | ||
| 8 | STATE STREET CORP | 1,268,686 | 62,048,000 | 3.40% | ||
| 9 | BlackRock Institutional Trust Company, N.A. | 879,001 | 42,992,000 | 2.36% | ||
| 10 | COLUMBIA WANGER ASSET MANAGEMENT LLC | 863,392 | 42,229,000 | 2.32% | ||
| 11 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 638,500 | 31,229,000 | 1.71% | ||
| 12 | GOLDMAN SACHS GROUP INC | 636,433 | 31,128,000 | 1.71% | ||
| 13 | JENNISON ASSOCIATES LLC | 498,041 | 24,359,000 | 1.34% | ||
| 14 | MILLENNIUM MANAGEMENT LLC | 461,245 | 22,559,000 | 1.24% | ||
| 15 | FEDERATED HERMES, INC. | 443,050 | 21,670,000 | 1.19% | ||
| 16 | NORTHERN TRUST CORP | 425,694 | 20,821,000 | 1.14% | ||
| 17 | ROCKEFELLER FINANCIAL SERVICES INC | 396,346 | 19,385,000 | 1.06% | ||
| 18 | OppenheimerFunds, Inc. | 391,313 | 19,139,000 | 1.05% | ||
| 19 | ALLIANCEBERNSTEIN L.P. | 378,195 | 18,498,000 | 1.01% | ||
| 20 | AMERIPRISE FINANCIAL INC | 349,253 | 17,085,000 | 0.94% | ||
| 21 | BLACKROCK ADVISORS LLC | 343,029 | 16,778,000 | 0.92% | ||
| 22 | EAGLE ASSET MANAGEMENT INC | 342,540 | 16,753,000 | 0.92% | ||
| 23 | WEATHERBIE CAPITAL, LLC | 337,788 | 16,521,000 | 0.91% | ||
| 24 | LORD, ABBETT & CO. LLC | 337,153 | 16,490,000 | 0.90% | ||
| 25 | NORGES BANK | 291,789 | 14,271,000 | 0.78% | ||
| 26 | PICTET ASSET MANAGEMENT LTD | 194,527 | 14,220,000 | 0.78% | ||
| 27 | JPMORGAN CHASE & CO | 263,337 | 12,881,000 | 0.71% | ||
| 28 | GEODE CAPITAL MANAGEMENT, LLC | 263,221 | 12,873,000 | 0.71% | ||
| 29 | BROWN ADVISORY INC | 261,583 | 12,794,000 | 0.70% | ||
| 30 | AXA S.A. | 227,213 | 11,113,000 | 0.61% | ||
| 31 | COLUMBUS CIRCLE INVESTORS | 186,015 | 9,098,000 | 0.50% | ||
| 32 | TEACHERS ADVISORS, LLC | 172,755 | 8,449,000 | 0.46% | ||
| 33 | Bank of New York Mellon Corp | 171,436 | 8,385,000 | 0.46% | ||
| 34 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 170,806 | 8,355,000 | 0.46% | ||
| 35 | ORBIMED ADVISORS LLC | 169,300 | 8,280,000 | 0.45% | ||
| 36 | DEUTSCHE BANK AG\ | 158,466 | 7,747,000 | 0.42% | ||
| 37 | TIAA CREF INVESTMENT MANAGEMENT LLC | 152,665 | 7,467,000 | 0.41% | ||
| 38 | BlackRock Investment Management, LLC | 152,553 | 7,461,000 | 0.41% | ||
| 39 | VOYA INVESTMENT MANAGEMENT LLC | 148,063 | 7,241,000 | 0.40% | ||
| 40 | Rock Springs Capital Management LP | 141,500 | 6,921,000 | 0.38% | ||
| 41 | CREDIT SUISSE AG/ | 141,187 | 6,905,000 | 0.38% | ||
| 42 | Iguana Healthcare Management, LLC | 140,000 | 6,847,000 | 0.38% | ||
| 43 | ROYAL BANK OF CANADA | 133,424 | 6,526,000 | 0.36% | ||
| 44 | BAKER BROS. ADVISORS LP | 110,894 | 5,424,000 | 0.30% | ||
| 45 | Cormorant Asset Management, LP | 110,842 | 5,421,000 | 0.30% | ||
| 46 | SPHERA FUNDS MANAGEMENT LTD. | 105,000 | 5,136,000 | 0.28% | ||
| 47 | HIGHLAND CAPITAL MANAGEMENT LP | 91,500 | 4,475,000 | 0.25% | ||
| 48 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 89,300 | 4,368,000 | 0.24% | Put | |
| 49 | Tekla Capital Management LLC | 88,400 | 4,324,000 | 0.24% | ||
| 50 | EVENTIDE ASSET MANAGEMENT, LLC | 87,400 | 4,275,000 | 0.23% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
