| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 5,380,827 | 550,943,000 | 16.47% | ||
| 2 | Capital Research Global Investors | 4,398,068 | 450,318,000 | 13.46% | ||
| 3 | COLUMBIA WANGER ASSET MANAGEMENT LLC | 2,334,173 | 238,996,000 | 7.14% | ||
| 4 | VANGUARD GROUP INC | 1,739,224 | 178,079,000 | 5.32% | ||
| 5 | WELLINGTON MANAGEMENT GROUP LLP | 1,672,780 | 171,275,000 | 5.12% | ||
| 6 | BlackRock Fund Advisors | 1,316,464 | 134,793,000 | 4.03% | ||
| 7 | PRICE T ROWE ASSOCIATES INC /MD/ | 1,179,140 | 120,732,000 | 3.61% | ||
| 8 | STATE STREET CORP | 837,050 | 85,705,000 | 2.56% | ||
| 9 | WELLS FARGO & COMPANY/MN | 828,545 | 84,835,000 | 2.54% | ||
| 10 | JENNISON ASSOCIATES LLC | 741,252 | 75,897,000 | 2.27% | ||
| 11 | LORD, ABBETT & CO. LLC | 727,659 | 74,505,000 | 2.23% | ||
| 12 | BlackRock Institutional Trust Company, N.A. | 725,209 | 74,254,000 | 2.22% | ||
| 13 | Visium Asset Management, LP | 668,238 | 68,420,000 | 2.05% | ||
| 14 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 625,000 | 63,994,000 | 1.91% | ||
| 15 | TPG Group Holdings (SBS) Advisors, Inc. | 596,420 | 61,067,000 | 1.83% | ||
| 16 | MILLENNIUM MANAGEMENT LLC | 484,180 | 49,575,000 | 1.48% | ||
| 17 | BLACKROCK ADVISORS LLC | 466,037 | 47,718,000 | 1.43% | ||
| 18 | FEDERATED HERMES, INC. | 398,600 | 40,813,000 | 1.22% | ||
| 19 | OppenheimerFunds, Inc. | 390,044 | 39,937,000 | 1.19% | ||
| 20 | ALLIANCEBERNSTEIN L.P. | 357,090 | 36,562,000 | 1.09% | ||
| 21 | RS INVESTMENT MANAGEMENT CO LLC | 349,113 | 35,746,000 | 1.07% | ||
| 22 | Polar Capital LLP | 262,061 | 26,832,000 | 0.80% | ||
| 23 | WEATHERBIE CAPITAL, LLC | 259,633 | 26,584,000 | 0.79% | ||
| 24 | NORGES BANK | 245,645 | 25,152,000 | 0.75% | ||
| 25 | FIL Ltd | 217,014 | 22,220,000 | 0.66% | ||
| 26 | FRANKLIN RESOURCES INC | 214,300 | 21,942,000 | 0.66% | ||
| 27 | Iguana Healthcare Management, LLC | 200,000 | 20,478,000 | 0.61% | ||
| 28 | GOLDMAN SACHS GROUP INC | 194,665 | 19,931,000 | 0.60% | ||
| 29 | GEODE CAPITAL MANAGEMENT, LLC | 189,299 | 19,382,000 | 0.58% | ||
| 30 | CITADEL ADVISORS LLC | 182,183 | 18,654,000 | 0.56% | ||
| 31 | Bank of New York Mellon Corp | 168,448 | 17,248,000 | 0.52% | ||
| 32 | BlackRock Investment Management, LLC | 148,529 | 15,208,000 | 0.45% | ||
| 33 | TWO SIGMA INVESTMENTS, LP | 145,341 | 14,881,000 | 0.44% | ||
| 34 | Weiss Multi-Strategy Advisers LLC | 143,432 | 14,686,000 | 0.44% | ||
| 35 | JPMORGAN CHASE & CO | 135,898 | 13,914,000 | 0.42% | ||
| 36 | NORTHERN TRUST CORP | 135,710 | 13,895,000 | 0.42% | ||
| 37 | BAKER BROS. ADVISORS LP | 123,894 | 12,686,000 | 0.38% | ||
| 38 | Allianz Asset Management GmbH | 120,625 | 12,351,000 | 0.37% | ||
| 39 | AXA S.A. | 115,652 | 11,842,000 | 0.35% | ||
| 40 | AMERIPRISE FINANCIAL INC | 112,497 | 11,517,000 | 0.34% | ||
| 41 | Opaleye Management Inc. | 110,000 | 11,263,000 | 0.34% | ||
| 42 | BROWN ADVISORY INC | 106,934 | 10,948,000 | 0.33% | ||
| 43 | BlackRock Group LTD | 106,809 | 10,936,000 | 0.33% | ||
| 44 | Cormorant Asset Management, LP | 102,000 | 10,444,000 | 0.31% | ||
| 45 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 92,657 | 9,488,000 | 0.28% | ||
| 46 | Rock Springs Capital Management LP | 92,000 | 9,420,000 | 0.28% | ||
| 47 | COLUMBIA PARTNERS L.L.C. INVESTMENT MANAGEMENT | 89,110 | 9,123,000 | 0.27% | ||
| 48 | FRED ALGER MANAGEMENT, LLC | 86,330 | 8,839,000 | 0.26% | ||
| 49 | EVENTIDE ASSET MANAGEMENT, LLC | 84,100 | 8,611,000 | 0.26% | ||
| 50 | Nationwide Fund Advisors | 74,119 | 7,589,000 | 0.23% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
