| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | AMICUS THERAPEUTICS INC | 14,439,444 | 204,318,000 | 12.30% | ||
| 2 | NEUROCRINE BIOSCIE COM USD0.001 | 3,284,467 | 156,866,000 | 9.45% | ||
| 3 | RETROPHIN INC COM | 2,820,875 | 91,650,000 | 5.52% | ||
| 4 | SAREPTA THERAPEUTICS INC | 2,809,528 | 85,494,000 | 5.15% | ||
| 5 | TESARO INC | 835,359 | 49,111,000 | 2.96% | ||
| 6 | DYAX CORP COM CVR | 1,786,315 | 47,337,000 | 2.85% | ||
| 7 | NEVRO CORP | 798,959 | 42,944,000 | 2.59% | ||
| 8 | XENCOR INC COM | 1,884,784 | 41,409,000 | 2.49% | ||
| 9 | SPDR SER TR | 150,000 | 37,836,000 | 2.28% | Put | |
| 10 | RELYPSA INC | 1,139,142 | 37,694,000 | 2.27% | ||
| 11 | IGNYTA INC COM | 1,967,600 | 29,691,000 | 1.79% | ||
| 12 | ACELRX PHARMACEUTICALS INC | 6,574,060 | 27,874,000 | 1.68% | ||
| 13 | Lion Biotechnologies | 2,759,593 | 25,305,000 | 1.52% | ||
| 14 | DERMA SCIENCES INC COM PAR .01 | 348,784 | 24,997,000 | 1.51% | ||
| 15 | GILEAD SCIENCES INC | 200,000 | 23,416,000 | 1.41% | Put | |
| 16 | ANI PHARMACEUTICALS INC COM | 327,157 | 20,300,000 | 1.22% | ||
| 17 | VERSARTIS INC COM | 1,321,400 | 20,112,000 | 1.21% | ||
| 18 | CEMPRA INC | 572,500 | 19,671,000 | 1.18% | ||
| 19 | PFENEX INC COM | 1,010,877 | 19,611,000 | 1.18% | ||
| 20 | ZS PHARMA INC | 361,777 | 18,953,000 | 1.14% | ||
| 21 | EAGLE PHARMACEUTICALS INC COM | 233,044 | 18,844,000 | 1.13% | ||
| 22 | ALLERGAN PLC | 59,185 | 17,960,000 | 1.08% | ||
| 23 | UNIQURE NV | 650,269 | 17,557,000 | 1.06% | ||
| 24 | ACADIA PHARMACEUTICALS | 410,240 | 17,181,000 | 1.03% | ||
| 25 | CHINA BIOLOGIC PRODS INC | 147,604 | 16,998,000 | 1.02% | ||
| 26 | Esperion Therapeutics Inc | 200,000 | 16,352,000 | 0.98% | Call | |
| 27 | RADIUS HEALTH | 235,530 | 15,945,000 | 0.96% | ||
| 28 | CAPITAL SR LIVING CORP COM | 640,500 | 15,692,000 | 0.94% | ||
| 29 | SAREPTA THERAPEUTICS INC | 500,000 | 15,215,000 | 0.92% | Call | |
| 30 | ASSEMBLY BIOSCIENCES INC | 784,893 | 15,117,000 | 0.91% | ||
| 31 | ZIMMER BIOMET HLDGS INC | 135,193 | 14,767,000 | 0.89% | ||
| 32 | MYLAN N V | 215,133 | 14,599,000 | 0.88% | ||
| 33 | HERON THERAPEUTICS INC | 448,000 | 13,960,000 | 0.84% | ||
| 34 | AFFIMED N V | 1,023,820 | 13,791,000 | 0.83% | ||
| 35 | ONCOTHYREON INC COM N/C EFF 6/ | 3,346,897 | 12,517,000 | 0.75% | ||
| 36 | BELLICUM PHARMACEUTICALS INC | 552,628 | 11,754,000 | 0.71% | ||
| 37 | PUMA BIOTECHNOLOGY | 100,000 | 11,675,000 | 0.70% | Call | |
| 38 | Receptos Inc | 60,969 | 11,587,000 | 0.70% | ||
| 39 | BLUEPRINT MEDICINES CORP COM | 404,404 | 10,712,000 | 0.65% | ||
| 40 | ANTHERA PHARMACEUTICALS I | 1,202,156 | 10,363,000 | 0.62% | ||
| 41 | ALLIQUA BIOMEDICAL INC | 1,921,951 | 10,128,000 | 0.61% | ||
| 42 | THORATEC LABS CORP | 226,000 | 10,073,000 | 0.61% | ||
| 43 | SHIRE PLC | 40,000 | 9,660,000 | 0.58% | ||
| 44 | SANGAMO BIOSCIENCES INCORPORATED | 800,000 | 8,872,000 | 0.53% | ||
| 45 | ACCELERON PHARMA | 276,036 | 8,734,000 | 0.53% | ||
| 46 | NEPTUNE TECHNOLOGIES BIORESO | 6,700,444 | 8,643,000 | 0.52% | ||
| 47 | QUOTIENT LTD | 562,436 | 8,577,000 | 0.52% | ||
| 48 | ANI PHARMACEUTICALS INC | 7,500,000 | 8,488,000 | 0.51% | PRN | |
| 49 | Otonomy Inc | 367,386 | 8,446,000 | 0.51% | ||
| 50 | COHERUS BIOSCIENCES INC COM | 258,716 | 7,477,000 | 0.45% |
Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001019056-15-000685, filed 2015.08.14).
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
