| 1 |
EcoR1 Capital, LLC |
1,986,413 |
4,132,000 |
29.96% |
|
|
| 2 |
Cormorant Asset Management, LP |
1,329,300 |
2,765,000 |
20.04% |
|
|
| 3 |
PERCEPTIVE ADVISORS LLC |
1,040,344 |
2,226,000 |
16.14% |
|
|
| 4 |
BlackRock Institutional Trust Company, N.A. |
784,724 |
1,632,000 |
11.83% |
|
|
| 5 |
SPHERA FUNDS MANAGEMENT LTD. |
558,325 |
1,195,000 |
8.66% |
|
|
| 6 |
ACUTA CAPITAL PARTNERS, LLC |
354,784 |
738,000 |
5.35% |
|
|
| 7 |
DAFNA Capital Management LLC |
200,000 |
416,000 |
3.02% |
|
|
| 8 |
VANGUARD GROUP INC |
120,683 |
258,000 |
1.87% |
|
|
| 9 |
GEODE CAPITAL MANAGEMENT, LLC |
55,302 |
118,000 |
0.86% |
|
|
| 10 |
GOLDMAN SACHS GROUP INC |
36,036 |
75,000 |
0.54% |
|
|
| 11 |
NORTHERN TRUST CORP |
26,289 |
55,000 |
0.40% |
|
|
| 12 |
RENAISSANCE TECHNOLOGIES LLC |
19,211 |
40,000 |
0.29% |
|
|
| 13 |
JBF Capital, Inc. |
11,800 |
25,000 |
0.18% |
|
|
| 14 |
Rotella Capital Management, Inc. |
11,300 |
24,000 |
0.17% |
|
|
| 15 |
Spark Investment Management LLC |
10,000 |
20,000 |
0.14% |
|
|
| 16 |
CITIGROUP INC |
8,398 |
18,000 |
0.13% |
|
|
| 17 |
BLACKROCK ADVISORS LLC |
8,267 |
17,000 |
0.12% |
|
|
| 18 |
UBS Group AG |
5,629 |
12,000 |
0.09% |
|
|
| 19 |
MORGAN STANLEY |
5,884 |
12,000 |
0.09% |
|
|
| 20 |
BlackRock Investment Management, LLC |
3,199 |
7,000 |
0.05% |
|
|
| 21 |
DEUTSCHE BANK AG\ |
3,252 |
6,000 |
0.04% |
|
|
| 22 |
BANK OF AMERICA CORP /DE/ |
500 |
1,000 |
0.01% |
|
|
| 23 |
BANK OF MONTREAL /CAN/ |
500 |
1,000 |
0.01% |
|
|
| 24 |
WELLS FARGO & COMPANY/MN |
500 |
1,000 |
0.01% |
|
|
| 25 |
Apriem Advisors |
100 |
0 |
0.00% |
|
|
| 26 |
LADENBURG THALMANN FINANCIAL SERVICES INC. |
150 |
0 |
0.00% |
|
|
| 27 |
Tower Research Capital LLC (TRC) |
183 |
0 |
0.00% |
|
|
