| 1 |
EcoR1 Capital, LLC |
1,920,913 |
3,534,000 |
36.15% |
|
|
| 2 |
Cormorant Asset Management, LP |
1,176,235 |
2,164,000 |
22.14% |
|
|
| 3 |
BlackRock Institutional Trust Company, N.A. |
801,249 |
1,474,000 |
15.08% |
|
|
| 4 |
PERCEPTIVE ADVISORS LLC |
615,844 |
1,133,000 |
11.59% |
|
|
| 5 |
VANGUARD GROUP INC |
186,100 |
343,000 |
3.51% |
|
|
| 6 |
SPHERA FUNDS MANAGEMENT LTD. |
186,500 |
343,000 |
3.51% |
|
|
| 7 |
GEODE CAPITAL MANAGEMENT, LLC |
155,348 |
285,000 |
2.92% |
|
|
| 8 |
DAFNA Capital Management LLC |
95,800 |
176,000 |
1.80% |
|
SH |
| 9 |
RENAISSANCE TECHNOLOGIES LLC |
65,700 |
121,000 |
1.24% |
|
|
| 10 |
GOLDMAN SACHS GROUP INC |
30,131 |
55,000 |
0.56% |
|
|
| 11 |
NORTHERN TRUST CORP |
22,032 |
40,000 |
0.41% |
|
|
| 12 |
NEXTHERA CAPITAL LP |
19,097 |
35,000 |
0.36% |
|
|
| 13 |
JBF Capital, Inc. |
11,800 |
22,000 |
0.23% |
|
|
| 14 |
BLACKROCK ADVISORS LLC |
8,267 |
15,000 |
0.15% |
|
|
| 15 |
UBS Group AG |
5,050 |
9,000 |
0.09% |
|
|
| 16 |
CITIGROUP INC |
4,048 |
7,000 |
0.07% |
|
|
| 17 |
BlackRock Investment Management, LLC |
2,984 |
5,000 |
0.05% |
|
|
| 18 |
BlackRock Fund Advisors |
2,328 |
4,000 |
0.04% |
|
|
| 19 |
MORGAN STANLEY |
2,330 |
4,000 |
0.04% |
|
|
| 20 |
Tower Research Capital LLC (TRC) |
1,125 |
2,000 |
0.02% |
|
|
| 21 |
WELLS FARGO & COMPANY/MN |
1,050 |
2,000 |
0.02% |
|
|
| 22 |
BANK OF AMERICA CORP /DE/ |
500 |
1,000 |
0.01% |
|
|
| 23 |
BANK OF MONTREAL /CAN/ |
500 |
1,000 |
0.01% |
|
|
| 24 |
GLOBEFLEX CAPITAL L P |
222 |
0 |
0.00% |
|
|
| 25 |
Apriem Advisors |
100 |
0 |
0.00% |
|
|
| 26 |
MSI Financial Services Inc |
138 |
0 |
0.00% |
|
|
| 27 |
BARCLAYS PLC |
200 |
0 |
0.00% |
|
|
| 28 |
Walleye Trading LLC |
100 |
0 |
0.00% |
|
|
| 29 |
LADENBURG THALMANN FINANCIAL SERVICES INC. |
150 |
0 |
0.00% |
|
|
