| 1 |
EcoR1 Capital, LLC |
1,986,413 |
4,589,000 |
35.41% |
|
|
| 2 |
Cormorant Asset Management, LP |
1,176,235 |
2,717,000 |
20.97% |
|
|
| 3 |
BlackRock Institutional Trust Company, N.A. |
801,249 |
1,851,000 |
14.28% |
|
|
| 4 |
PERCEPTIVE ADVISORS LLC |
615,844 |
1,423,000 |
10.98% |
|
|
| 5 |
SPHERA FUNDS MANAGEMENT LTD. |
360,325 |
832,000 |
6.42% |
|
|
| 6 |
VANGUARD GROUP INC |
162,800 |
376,000 |
2.90% |
|
|
| 7 |
GEODE CAPITAL MANAGEMENT, LLC |
155,296 |
358,000 |
2.76% |
|
|
| 8 |
JENNISON ASSOCIATES LLC |
98,368 |
227,000 |
1.75% |
|
|
| 9 |
DAFNA Capital Management LLC |
95,800 |
221,000 |
1.71% |
|
SH |
| 10 |
RENAISSANCE TECHNOLOGIES LLC |
56,900 |
131,000 |
1.01% |
|
|
| 11 |
GOLDMAN SACHS GROUP INC |
26,959 |
62,000 |
0.48% |
|
|
| 12 |
NORTHERN TRUST CORP |
22,032 |
51,000 |
0.39% |
|
|
| 13 |
JBF Capital, Inc. |
11,800 |
27,000 |
0.21% |
|
|
| 14 |
MORGAN STANLEY |
8,720 |
20,000 |
0.15% |
|
|
| 15 |
UBS Group AG |
8,150 |
19,000 |
0.15% |
|
|
| 16 |
BLACKROCK ADVISORS LLC |
8,267 |
19,000 |
0.15% |
|
|
| 17 |
CITIGROUP INC |
8,000 |
18,000 |
0.14% |
|
|
| 18 |
BlackRock Investment Management, LLC |
2,984 |
7,000 |
0.05% |
|
|
| 19 |
Lehman Financial Resources, Inc. |
1,500 |
3,000 |
0.02% |
|
|
| 20 |
WELLS FARGO & COMPANY/MN |
1,000 |
2,000 |
0.02% |
|
|
| 21 |
Walleye Trading LLC |
1,000 |
2,000 |
0.02% |
|
|
| 22 |
BANK OF AMERICA CORP /DE/ |
500 |
1,000 |
0.01% |
|
|
| 23 |
BANK OF MONTREAL /CAN/ |
500 |
1,000 |
0.01% |
|
|
| 24 |
GLOBEFLEX CAPITAL L P |
222 |
1,000 |
0.01% |
|
|
| 25 |
Brookstone Capital Management |
240 |
1,000 |
0.01% |
|
|
| 26 |
LADENBURG THALMANN FINANCIAL SERVICES INC. |
150 |
0 |
0.00% |
|
|
| 27 |
Apriem Advisors |
100 |
0 |
0.00% |
|
|
