| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Birchview Capital, LP | 2,155,795 | 46,328,000 | 15.96% | ||
| 2 | Miura Global Management, LLC | 1,500,000 | 32,235,000 | 11.10% | ||
| 3 | VANGUARD GROUP INC | 1,007,160 | 21,643,000 | 7.46% | ||
| 4 | Cannell & Co. | 1,046,239 | 21,169,000 | 7.29% | ||
| 5 | J.P. Morgan Private Wealth Advisors LLC | 757,000 | 16,268,000 | 5.60% | ||
| 6 | FMR LLC | 590,000 | 12,679,000 | 4.37% | ||
| 7 | BlackRock Institutional Trust Company, N.A. | 565,424 | 12,151,000 | 4.19% | ||
| 8 | Nuveen Asset Management, LLC | 545,321 | 11,719,000 | 4.04% | ||
| 9 | BlackRock Fund Advisors | 535,835 | 11,515,000 | 3.97% | ||
| 10 | ArrowMark Colorado Holdings LLC | 370,785 | 7,968,000 | 2.74% | ||
| 11 | STATE STREET CORP | 359,832 | 7,732,000 | 2.66% | ||
| 12 | WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | 334,349 | 7,185,000 | 2.48% | ||
| 13 | Selkirk Management LLC | 322,517 | 6,931,000 | 2.39% | ||
| 14 | Tekla Capital Management LLC | 264,625 | 5,687,000 | 1.96% | ||
| 15 | NORTHERN TRUST CORP | 263,908 | 5,672,000 | 1.95% | ||
| 16 | GEODE CAPITAL MANAGEMENT, LLC | 177,470 | 3,813,000 | 1.31% | ||
| 17 | Iguana Healthcare Management, LLC | 175,000 | 3,761,000 | 1.30% | ||
| 18 | DRIEHAUS CAPITAL MANAGEMENT LLC | 158,808 | 3,413,000 | 1.18% | ||
| 19 | Visium Asset Management, LP | 150,000 | 3,224,000 | 1.11% | ||
| 20 | UBS Group AG | 127,513 | 2,740,000 | 0.94% | ||
| 21 | Alyeska Investment Group, L.P. | 125,000 | 2,686,000 | 0.93% | ||
| 22 | Bank of New York Mellon Corp | 123,491 | 2,654,000 | 0.91% | ||
| 23 | DSC Advisors, L.P. | 113,862 | 2,447,000 | 0.84% | ||
| 24 | Avoro Capital Advisors LLC | 112,885 | 2,426,000 | 0.84% | ||
| 25 | RTW INVESTMENTS, LP | 105,468 | 2,267,000 | 0.78% | ||
| 26 | Harvest Capital Strategies LLC | 100,000 | 2,149,000 | 0.74% | Put | |
| 27 | Harvest Capital Strategies LLC | 100,000 | 2,149,000 | 0.74% | ||
| 28 | Opaleye Management Inc. | 75,000 | 1,612,000 | 0.56% | ||
| 29 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 74,857 | 1,609,000 | 0.55% | ||
| 30 | BlackRock Investment Management, LLC | 73,196 | 1,573,000 | 0.54% | ||
| 31 | TIAA CREF INVESTMENT MANAGEMENT LLC | 71,812 | 1,543,000 | 0.53% | ||
| 32 | ALBION FINANCIAL GROUP /UT | 63,093 | 1,356,000 | 0.47% | ||
| 33 | Neuberger Berman Group LLC | 48,500 | 1,042,000 | 0.36% | ||
| 34 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 43,900 | 943,000 | 0.32% | Put | |
| 35 | Swiss National Bank | 43,500 | 935,000 | 0.32% | ||
| 36 | UBS Group AG | 40,000 | 860,000 | 0.30% | Call | |
| 37 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 39,832 | 856,000 | 0.29% | ||
| 38 | CHARTIST INC /CA/ | 38,939 | 836,799 | 0.29% | ||
| 39 | MORGAN STANLEY | 37,830 | 814,000 | 0.28% | ||
| 40 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 35,300 | 759,000 | 0.26% | ||
| 41 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 34,500 | 741,000 | 0.26% | Call | |
| 42 | TEACHERS ADVISORS, LLC | 32,831 | 706,000 | 0.24% | ||
| 43 | BLAIR WILLIAM & CO/IL | 32,335 | 694,000 | 0.24% | ||
| 44 | Coe Capital Management, LLC | 32,082 | 689,442 | 0.24% | ||
| 45 | WELLS FARGO & COMPANY/MN | 31,779 | 683,000 | 0.24% | ||
| 46 | ALLIANCEBERNSTEIN L.P. | 37,310 | 604,000 | 0.21% | ||
| 47 | MILLENNIUM MANAGEMENT LLC | 25,898 | 557,000 | 0.19% | ||
| 48 | Geneva Advisors, LLC | 25,246 | 543,000 | 0.19% | ||
| 49 | CREDIT SUISSE AG/ | 24,563 | 528,000 | 0.18% | ||
| 50 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 21,997 | 473,000 | 0.16% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
