| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | ALNYLAM PHARMACEUTICALS INC | 562,697 | 52,972,000 | 17.56% | ||
| 2 | LA JOLLA PHARMACEUTICAL CO | 1,064,247 | 28,735,000 | 9.53% | ||
| 3 | OMEROS CORP | 1,785,502 | 28,086,000 | 9.31% | ||
| 4 | KITE PHARMA INCORPORATED | 411,143 | 25,335,000 | 8.40% | ||
| 5 | Dicerna Pharmaceuticals | 1,975,229 | 23,446,000 | 7.77% | ||
| 6 | ACHILLION PHARMACEUTICALS INC COM | 1,951,922 | 21,061,000 | 6.98% | ||
| 7 | BIOCRYST PHARMACEUTICALS | 1,973,108 | 20,362,000 | 6.75% | ||
| 8 | MIRATI THERAPEUTICS INC COM | 378,287 | 11,954,000 | 3.96% | ||
| 9 | Atara Biotherapeutics Inc | 425,852 | 11,247,000 | 3.73% | ||
| 10 | FIVE PRIME THERAPEUTICS INC | 252,452 | 10,477,000 | 3.47% | ||
| 11 | AGENUS INC | 2,173,267 | 9,867,000 | 3.27% | ||
| 12 | CELLDEX THERAPEUTICS INC NEW | 625,386 | 9,806,000 | 3.25% | ||
| 13 | SYMMETRY SURGICAL INC | 863,264 | 7,942,000 | 2.63% | ||
| 14 | BRISTOL MYERS SQUIBB CO | 104,330 | 7,177,000 | 2.38% | ||
| 15 | CORIUM INTERNATIONAL INC | 730,031 | 5,928,000 | 1.97% | ||
| 16 | GLOBAL BLOOD THERAPEUTICS IN COM | 171,898 | 5,558,000 | 1.84% | ||
| 17 | DYAX CORP COM CVR | 113,641 | 4,275,000 | 1.42% | ||
| 18 | REGENXBIO INC COM | 217,210 | 3,606,000 | 1.20% | ||
| 19 | LIPOCINE INC NEW | 216,414 | 2,798,000 | 0.93% | ||
| 20 | ACCELERATE DIAGNOSTICS INC | 105,468 | 2,267,000 | 0.75% | ||
| 21 | INVUITY INC | 202,808 | 1,789,000 | 0.59% | ||
| 22 | CYTRX CORP | 461,824 | 1,224,000 | 0.41% | ||
| 23 | MASIMO CORP COM | 25,900 | 1,075,000 | 0.36% | ||
| 24 | ANIKA THERAPEUTICS INC COM | 27,500 | 1,049,000 | 0.35% | ||
| 25 | ALLSCRIPTS HEALTHCARE | 48,000 | 738,000 | 0.24% | ||
| 26 | BIOPHARMX CORP COM | 370,636 | 563,000 | 0.19% | ||
| 27 | GENOMIC HEALTH INC COM | 15,000 | 528,000 | 0.18% | ||
| 28 | NATERA INC | 31,693 | 342,000 | 0.11% | ||
| 29 | BLUEBIRD BIO INCORPORATED | 5,300 | 340,000 | 0.11% | ||
| 30 | Nivalis Therapeutics Inc | 30,000 | 232,000 | 0.08% | ||
| 31 | T2 BIOSYSTEMS INC | 20,900 | 229,000 | 0.08% | ||
| 32 | VERACYTE INC | 25,000 | 180,000 | 0.06% | ||
| 33 | ENDOLOGIX INC | 15,000 | 149,000 | 0.05% | ||
| 34 | MERIDIAN BIOSCIENCE INC COM | 1,252 | 110,000 | 0.04% | Call | |
| 35 | ADAPTIMMUNE THERAPEUTICS PLC | 6,923 | 83,000 | 0.03% | ||
| 36 | NEVRO CORP | 142 | 37,000 | 0.01% | Put | |
| 37 | UNITED STATES | 13,850 | 7,000 | 0.00% | Call | |
| 38 | BERKSHIRE HATHAWAY INC DEL | 50 | 7,000 | 0.00% |
Portfolio data is normalized using SEC Form 13F filings, including the Restatement filing (0001493152-16-010244, filed 2016.05.24).
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
