| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 6,083,484 | 206,109,000 | 13.63% | ||
| 2 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 3,227,923 | 109,362,000 | 7.23% | ||
| 3 | VANGUARD GROUP INC | 2,827,624 | 95,800,000 | 6.34% | ||
| 4 | BlackRock Fund Advisors | 2,600,475 | 88,104,000 | 5.83% | ||
| 5 | EAGLE ASSET MANAGEMENT INC | 2,472,471 | 83,767,000 | 5.54% | ||
| 6 | ORACLE INVESTMENT MANAGEMENT INC | 1,851,077 | 62,714,000 | 4.15% | ||
| 7 | STATE STREET CORP | 1,281,361 | 43,411,000 | 2.87% | ||
| 8 | PFM Health Sciences, LP | 1,226,077 | 41,539,000 | 2.75% | ||
| 9 | BlackRock Institutional Trust Company, N.A. | 1,193,265 | 40,428,000 | 2.67% | ||
| 10 | WELLINGTON MANAGEMENT GROUP LLP | 1,106,144 | 37,476,000 | 2.48% | ||
| 11 | Clearbridge Investments, LLC | 1,007,432 | 34,132,000 | 2.26% | ||
| 12 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 1,000,000 | 33,880,000 | 2.24% | ||
| 13 | THRIVENT FINANCIAL FOR LUTHERANS | 916,810 | 31,061,000 | 2.05% | ||
| 14 | BAKER BROS. ADVISORS LP | 753,391 | 25,525,000 | 1.69% | ||
| 15 | Penn Capital Management Company, LLC | 684,455 | 23,189,000 | 1.53% | ||
| 16 | DIMENSIONAL FUND ADVISORS LP | 663,130 | 22,470,000 | 1.49% | ||
| 17 | BRIDGER MANAGEMENT, LLC | 656,511 | 22,243,000 | 1.47% | ||
| 18 | VOYA INVESTMENT MANAGEMENT LLC | 548,112 | 18,570,000 | 1.23% | ||
| 19 | Visium Asset Management, LP | 530,000 | 17,956,000 | 1.19% | ||
| 20 | NORTHERN TRUST CORP | 509,685 | 17,268,000 | 1.14% | ||
| 21 | Bank of New York Mellon Corp | 473,860 | 16,055,000 | 1.06% | ||
| 22 | Invesco Ltd. | 473,355 | 16,038,000 | 1.06% | ||
| 23 | JENNISON ASSOCIATES LLC | 419,895 | 14,226,000 | 0.94% | ||
| 24 | TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY | 389,700 | 13,203,000 | 0.87% | ||
| 25 | NORGES BANK | 373,356 | 12,649,000 | 0.84% | ||
| 26 | LOOMIS SAYLES & CO L P | 358,791 | 12,156,000 | 0.80% | ||
| 27 | BLACKROCK ADVISORS LLC | 356,373 | 12,074,000 | 0.80% | ||
| 28 | TEACHERS ADVISORS, LLC | 310,151 | 10,508,000 | 0.70% | ||
| 29 | PRICE T ROWE ASSOCIATES INC /MD/ | 308,636 | 10,457,000 | 0.69% | ||
| 30 | March Altus Capital Management LP | 303,484 | 10,282,000 | 0.68% | ||
| 31 | MILLENNIUM MANAGEMENT LLC | 283,759 | 9,614,000 | 0.64% | ||
| 32 | GEODE CAPITAL MANAGEMENT, LLC | 279,211 | 9,459,000 | 0.63% | ||
| 33 | Tekla Capital Management LLC | 273,162 | 9,255,000 | 0.61% | ||
| 34 | PRINCIPAL FINANCIAL GROUP INC | 259,690 | 8,799,000 | 0.58% | ||
| 35 | Artal Group S.A. | 250,000 | 8,470,000 | 0.56% | ||
| 36 | RUSSELL FRANK CO/ | 239,346 | 8,109,000 | 0.54% | ||
| 37 | NEW YORK STATE COMMON RETIREMENT FUND | 238,046 | 8,065,000 | 0.53% | ||
| 38 | GOLDMAN SACHS GROUP INC | 236,271 | 8,004,000 | 0.53% | ||
| 39 | TIAA CREF INVESTMENT MANAGEMENT LLC | 218,780 | 7,412,000 | 0.49% | ||
| 40 | BANK OF AMERICA CORP /DE/ | 206,458 | 6,995,000 | 0.46% | ||
| 41 | SPHERA FUNDS MANAGEMENT LTD. | 199,105 | 6,746,000 | 0.45% | ||
| 42 | AMERIPRISE FINANCIAL INC | 195,885 | 6,637,000 | 0.44% | ||
| 43 | MACQUARIE GROUP LTD | 184,095 | 6,237,000 | 0.41% | ||
| 44 | SECTOR GAMMA AS | 176,600 | 5,983,000 | 0.40% | ||
| 45 | PRUDENTIAL FINANCIAL INC | 161,152 | 5,460,000 | 0.36% | ||
| 46 | PANAGORA ASSET MANAGEMENT INC | 156,872 | 5,315,000 | 0.35% | ||
| 47 | BlackRock Investment Management, LLC | 152,384 | 5,163,000 | 0.34% | ||
| 48 | Gotham Asset Management, LLC | 150,609 | 5,103,000 | 0.34% | ||
| 49 | STRS OHIO | 150,200 | 5,089,000 | 0.34% | ||
| 50 | MANAGED ACCOUNT ADVISORS LLC | 147,655 | 5,002,000 | 0.33% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
