| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 4,282,300 | 162,342,000 | 10.51% | ||
| 2 | BlackRock Fund Advisors | 2,794,835 | 105,952,000 | 6.86% | ||
| 3 | VANGUARD GROUP INC | 2,773,141 | 105,129,000 | 6.81% | ||
| 4 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 2,663,708 | 100,980,000 | 6.54% | ||
| 5 | EAGLE ASSET MANAGEMENT INC | 2,109,592 | 79,974,000 | 5.18% | ||
| 6 | ORACLE INVESTMENT MANAGEMENT INC | 1,956,414 | 74,167,655 | 4.80% | ||
| 7 | STATE STREET CORP | 1,389,691 | 52,678,000 | 3.41% | ||
| 8 | Invesco Ltd. | 1,252,426 | 47,480,000 | 3.07% | ||
| 9 | BlackRock Institutional Trust Company, N.A. | 1,202,262 | 45,578,000 | 2.95% | ||
| 10 | WELLINGTON MANAGEMENT GROUP LLP | 1,177,803 | 44,650,000 | 2.89% | ||
| 11 | GOLDMAN SACHS GROUP INC | 1,155,415 | 43,802,000 | 2.84% | ||
| 12 | BAKER BROS. ADVISORS LP | 1,000,000 | 37,910,000 | 2.45% | ||
| 13 | Clearbridge Investments, LLC | 997,820 | 37,827,000 | 2.45% | ||
| 14 | FRANKLIN RESOURCES INC | 942,450 | 35,728,000 | 2.31% | ||
| 15 | THRIVENT FINANCIAL FOR LUTHERANS | 891,100 | 33,781,000 | 2.19% | ||
| 16 | PFM Health Sciences, LP | 723,621 | 27,432,000 | 1.78% | ||
| 17 | BLACKROCK ADVISORS LLC | 703,240 | 26,660,000 | 1.73% | ||
| 18 | DIMENSIONAL FUND ADVISORS LP | 672,694 | 25,502,000 | 1.65% | ||
| 19 | VOYA INVESTMENT MANAGEMENT LLC | 621,201 | 23,549,000 | 1.52% | ||
| 20 | THOMPSON SIEGEL & WALMSLEY LLC | 588,665 | 22,317,000 | 1.44% | ||
| 21 | NORTHERN TRUST CORP | 571,020 | 21,647,000 | 1.40% | ||
| 22 | Bank of New York Mellon Corp | 509,444 | 19,313,000 | 1.25% | ||
| 23 | PointState Capital LP | 500,000 | 18,955,000 | 1.23% | ||
| 24 | TEACHERS ADVISORS, LLC | 389,511 | 14,766,000 | 0.96% | ||
| 25 | SAC Capital Advisors LP | 370,900 | 14,061,000 | 0.91% | ||
| 26 | TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY | 357,100 | 13,538,000 | 0.88% | ||
| 27 | Artal Group S.A. | 350,000 | 13,269,000 | 0.86% | ||
| 28 | Penn Capital Management Company, LLC | 340,688 | 12,915,000 | 0.84% | ||
| 29 | NORGES BANK | 337,452 | 12,793,000 | 0.83% | ||
| 30 | PRICE T ROWE ASSOCIATES INC /MD/ | 308,936 | 11,712,000 | 0.76% | ||
| 31 | PRINCIPAL FINANCIAL GROUP INC | 263,082 | 9,973,000 | 0.65% | ||
| 32 | PRUDENTIAL FINANCIAL INC | 262,352 | 9,946,000 | 0.64% | ||
| 33 | SECTOR GAMMA AS | 250,700 | 9,504,000 | 0.62% | ||
| 34 | BANK OF AMERICA CORP /DE/ | 221,066 | 8,381,000 | 0.54% | ||
| 35 | BlackRock Group LTD | 220,703 | 8,367,000 | 0.54% | ||
| 36 | GEODE CAPITAL MANAGEMENT, LLC | 220,625 | 8,363,000 | 0.54% | ||
| 37 | RENAISSANCE TECHNOLOGIES LLC | 217,561 | 8,248,000 | 0.53% | ||
| 38 | TIAA CREF INVESTMENT MANAGEMENT LLC | 216,629 | 8,212,000 | 0.53% | ||
| 39 | CITADEL ADVISORS LLC | 212,521 | 8,056,000 | 0.52% | ||
| 40 | NEW YORK STATE COMMON RETIREMENT FUND | 186,111 | 7,055,000 | 0.46% | ||
| 41 | AMERIPRISE FINANCIAL INC | 173,287 | 6,569,000 | 0.43% | ||
| 42 | GUGGENHEIM CAPITAL LLC | 148,721 | 5,638,000 | 0.37% | ||
| 43 | J. Goldman & Co LP | 144,375 | 5,473,000 | 0.35% | ||
| 44 | BlackRock Investment Management, LLC | 134,847 | 5,112,000 | 0.33% | ||
| 45 | Allianz Asset Management GmbH | 129,840 | 4,922,000 | 0.32% | ||
| 46 | MACQUARIE GROUP LTD | 126,632 | 4,801,000 | 0.31% | ||
| 47 | MANAGED ACCOUNT ADVISORS LLC | 126,195 | 4,784,000 | 0.31% | ||
| 48 | Tekla Capital Management LLC | 112,881 | 4,279,000 | 0.28% | ||
| 49 | WELLS FARGO & COMPANY/MN | 110,768 | 4,200,000 | 0.27% | ||
| 50 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 109,669 | 4,158,000 | 0.27% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
