| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | SPDR S&P 500 ETF TR PUT | 14,000 | 302,820,000 | 11.34% | Put | |
| 2 | ELI LILLY & CO | 29,347 | 235,539,000 | 8.82% | Call | |
| 3 | SPDR S&P 500 ETF TR | 10,000 | 216,300,000 | 8.10% | Call | |
| 4 | ISHARES TR | 14,892 | 184,973,000 | 6.93% | Put | |
| 5 | SAREPTA THERAPEUTICS INC | 26,748 | 164,259,000 | 6.15% | Put | |
| 6 | GILEAD SCIENCES INC | 11,691 | 92,499,000 | 3.47% | Call | |
| 7 | REGENERON PHARMACEUTICALS INC | 1,792 | 72,042,000 | 2.70% | Put | |
| 8 | iShares MSCI EAFE Call Opt 06/17 65 | 5,441 | 67,583,000 | 2.53% | Call | |
| 9 | HCA HOLDINGS INC | 7,680 | 58,084,000 | 2.18% | Call | |
| 10 | MONSANTO CALL | 5,607 | 57,304,000 | 2.15% | Call | |
| 11 | AMGEN INC | 2,569 | 42,853,000 | 1.61% | Put | |
| 12 | ELI LILLY & CO | 4,898 | 39,311,000 | 1.47% | Put | |
| 13 | CELGENE CORP | 3,451 | 36,073,000 | 1.35% | Call | |
| 14 | SAREPTA THERAPEUTICS INC | 536,282 | 32,933,000 | 1.23% | ||
| 15 | REGENERON PHARMACEUTICALS | 75,919 | 30,521,000 | 1.14% | ||
| 16 | BRISTOL MYERS SQUIBB CO | 5,409 | 29,165,000 | 1.09% | Call | |
| 17 | ALKERMES PLC | 3,249 | 28,201,000 | 1.06% | Call | |
| 18 | MERCK & CO | 4,487 | 28,003,000 | 1.05% | Call | |
| 19 | ABBVIE INC | 4,136 | 26,086,000 | 0.98% | Call | |
| 20 | CELGENE CORP | 2,415 | 25,244,000 | 0.95% | Put | |
| 21 | ACADIA HEALTHCARE COMPANY IN | 7,784 | 24,761,000 | 0.93% | Call | |
| 22 | AMGEN INC | 133,176 | 22,215,000 | 0.83% | ||
| 23 | AGIOS PHARMACEUTICALS INC | 4,108 | 21,698,000 | 0.81% | Call | |
| 24 | SAREPTA THERAPEUTICS INC CALL | 3,526 | 21,653,000 | 0.81% | Call | |
| 25 | ABBOTT LABS | 5,000 | 21,145,000 | 0.79% | Put | |
| 26 | CLOVIS ONCOLOGY INC | 5,850 | 21,089,000 | 0.79% | Call | |
| 27 | BIOGEN INC | 667 | 20,879,000 | 0.78% | Call | |
| 28 | EXPRESS SCRIPTS HOLDING CO | 2,897 | 20,433,000 | 0.77% | Call | |
| 29 | BRISTOL MYERS SQUIBB CO | 3,469 | 18,705,000 | 0.70% | Put | |
| 30 | VERTEX PHARMACEUTICALS INC | 1,955 | 17,050,000 | 0.64% | Call | |
| 31 | CEMPRA INC | 6,323 | 15,302,000 | 0.57% | Put | |
| 32 | RETROPHIN INC | 6,293 | 14,084,000 | 0.53% | Call | |
| 33 | PUMA BIOTECHNOLOGY INC | 2,021 | 13,551,000 | 0.51% | Call | |
| 34 | SHIRE PLC | 698 | 13,531,000 | 0.51% | Put | |
| 35 | SHIRE PLC | 698 | 13,531,000 | 0.51% | Call | |
| 36 | SPDR S&P BIOTECH ETF | 1,958 | 12,980,000 | 0.49% | Put | |
| 37 | UNITED THERAPEUTICS CORP | 1,098 | 12,965,000 | 0.49% | Put | |
| 38 | HUMANA INC | 700 | 12,382,000 | 0.46% | Put | |
| 39 | EXPRESS SCRIPTS HOLDING CO | 1,691 | 11,927,000 | 0.45% | Put | |
| 40 | AstraZeneca PLC | 3,520 | 11,567,000 | 0.43% | Call | |
| 41 | LEXICON PHARMACEUTICALS INC | 6,263 | 11,317,000 | 0.42% | Call | |
| 42 | HESS CORP | 2,059 | 11,040,000 | 0.41% | Call | |
| 43 | DEPOMED INC | 4,321 | 10,798,000 | 0.40% | Call | |
| 44 | MYLAN N.V. | 2,804 | 10,689,000 | 0.40% | Call | |
| 45 | DYNAVAX TECHNOLOGIES CORP | 9,984 | 10,473,000 | 0.39% | Call | |
| 46 | ALNYLAM PHARMACEUTICALS INC | 1,448 | 9,815,000 | 0.37% | Call | |
| 47 | ONCOBIOLOGICS INC | 2,268,585 | 9,643,000 | 0.36% | ||
| 48 | BLUEBIRD BIO INC | 1,380 | 9,354,000 | 0.35% | Call | |
| 49 | BRISTOL MYERS SQUIBB CO | 156,887 | 8,459,000 | 0.32% | ||
| 50 | DYNAVAX TECHNOLOGIES CORP | 7,628 | 8,002,000 | 0.30% | Put |
Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001144204-16-133740, filed 2016.11.14).
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
